FullText URL 126_79.pdf
Author 岡山医学会|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 79
End Page 80
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
Title Alternative The 44th Okayama Rheumatology Conference
FullText URL 126_75.pdf
Author 岡山リウマチ研究会|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 75
End Page 77
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.75
Title Alternative The 10th Congress on Neutron Capture Therapy
FullText URL 126_73.pdf
Author Matsui, Hideki|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 73
End Page 74
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.73
FullText URL 126_71.pdf
Author 浜田 史洋|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 71
End Page 72
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
FullText URL 126_69.pdf
Author 雁木 淳一|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 69
End Page 70
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
Title Alternative SFTS : Severe fever with thrombocytopenia syndrome
FullText URL 126_65.pdf
Author Watanabe, Tokiko| Kusano, Nobuchika| Iwatsuki, Keiji|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 65
End Page 67
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.65
Title Alternative Drug interaction (29. drug interaction of steroids)
FullText URL 126_59.pdf
Author Hayashi, Youko| Nawa, Hideki| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 59
End Page 63
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.59
Author Morimoto, Nobutoshi| Abe, Koji|
Published Date 2014-04-01
Publication Title 岡山医学会雑誌
Volume volume126
Issue issue1
Content Type Journal Article
Title Alternative Molecular targeted therapies in leukemia
FullText URL 126_49.pdf
Author Maeda, Yoshinobu| Tanimoto, Mitsune|
Keywords 白血病 分子標的薬 チロシンキナーゼ阻害薬
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 49
End Page 54
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.49
Title Alternative A patient with primary malignant melanoma of the esophagus who underwent esophagectomy
FullText URL 126_45.pdf
Author Maeda, Naoaki| Shirakawa, Yasuhiro| Koujima, Takeshi| Ohara, Toshiaki| Tanabe, Shunsuke| Noma, Kazuhiro| Sakurama, Kazuhumi| Fujiwara, Toshiyosi|
Abstract  We report the case of a 61-old-man with a primary malignant melanoma of the esophagus, an extremely rare and highly aggressive malignancy. He presented with dysphagia, and we performed an upper gastrointestinal endoscopy that detected a tumor in the thoracic part of the esophagus. The biopsy showed malignant melanoma. PET/CT, endoscopy and an esophagogram showed that a 70-mm scaled type 2+1 tumor in the thoracic esophagus and no metastases. We diagnosed a cT3cN0cM0 cStage II tumor. We then performed a subtotal esophagectomy with two-field lymph node dissection and esophagogastrostomy via a retrosternal route. The pathological examination of the resected specimens confirmed that the type 2+1 tumor was PMME (pT2N0M0 pStage II). We administered six courses of postoperative adjuvant chemotherapy with dacarbazine, and the patient has had no recurrence for 17 months after the surgery.
Keywords 食道(esophagus) 悪性黒色腫(malignant melanoma)
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 45
End Page 48
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.45
Title Alternative Complete response of primary esophageal endocrine cell carcinoma resected after neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil
FullText URL 126_39.pdf
Author Maeda, Naoaki| Shirakawa, Yasuhiro| Koujima, Takeshi| Ohara, Toshiaki| Tanabe, Shunsuke| Noma, Kazuhiro| Sakurama, Kazuhumi| Fujiwara, Toshiyosi|
Abstract  Esophageal endocrine cell carcinoma is extremely rare. We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). A 66-year-old man had been experiencing epigastralgia, and a type 2 tumor in the thoracic part of esophagus was detected by upper endoscopy. The biopsy showed endocrine cell carcinoma. PET/CT, endoscopy and an esophagogram showed that the patient had a 70-mm scaled type 2 tumor in the middle thoracic esophagus, and they also revealed lymph node metastases (no. 106recR). We diagnosed a cT3cN1cM0 cStage III tumor. With two courses of DCF treatment, both the primary tumor and lymph node metastases showed a partial response. We performed a subtotal esophagectomy with three-field lymph node dissection. The pathological examination of the resected specimens revealed no malignant cells in the esophagus or lymph nodes, and we concluded that the pathological effect of the DCF treatment was Grade 3.
Keywords 食道癌(esophageal cancer) 内分泌細胞癌(endocrine cell carcinoma) DCF療法(DCF treatment)
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 39
End Page 43
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.39
Title Alternative A case of colon lipoma presenting with intussusception
FullText URL 126_35.pdf
Author Ninomiya, Takayuki| Ojima, Yasutomo| Harano, Masao| Ohno, Satoshi| Shiozaki, Shigehiro| Ninomiya, Motoki|
Abstract  An 84-year-old man, who had been found to have a submucosal tumor in the ascending colon two years before, was admitted to our hospital for right lower quadrant abdominal pain and melena. An abdominal computed tomography (CT) scan showed intussusception in the ascending colon, resulting from a fat-density tumor. The intussusception was located by colonoscopy. Since the colonic tumor was enlarged in comparison with two years ago and had an ulcer at the top of the tumor, there was the possibility of malignancy and recurrence of intussusception. He underwent a laparoscopy-assisted right colectomy with lymph node dissection. Pathologically, the tumor of the ascending colon was a benign lipoma.
Keywords 結腸脂肪腫(lipoma of the colon) 腸重積(intussusception) 腹腔鏡下手術(laparoscopic surgery)
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 35
End Page 38
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.35
Title Alternative Metastatic breast cancer presenting as severe anemia, platelet reduction and abnormal cells in peripheral blood
FullText URL 126_31.pdf
Author Ota, Seisuke| Kasahara, Akinori| Mizuno, Shoma| Fukatsu, Haruka| Kinoshita, Osamu| Noguchi, Toshio| Kishimoto, Nobuyasu| Matsumura, Tadashi|
Abstract  Worldwide, breast cancer accounts for 22.9% of all cancers excluding non-melanoma skin cancers in women. More than 80% of breast cancer cases are discovered when a woman discovers a lump that feels different from the rest of the breast tissue. We report the case of a 60-year-old woman who had been treated for one year at a psychiatric hospital for suspected schizophrenia, and was referred to our hospital on March 23, 2011 for consultation regarding complete blood count abnormalities: hemoglobin, 4.8g/㎗ ; Plt, 1.9×104/μl ; WBC, 12,700/μl with 18.5% abnormal cells. Computed tomography revealed an enhanced, irregular mass in her right breast as well as right axillary lymph node swelling, suggestive of breast cancer. BM biopsy confirmed the presence of abnormal, keratin-positive cells, suggesting metastasis to the bone. CA15-3 was 300U/㎖ (normal range <25). The patient died on April 11, 2011, post-admission day 20. We found a rare case of terminal breast cancer that presented with peripheral blood abnormality. Breast cancer in patients who do not notice breast abnormality can present with peripheral blood abnormality.
Keywords 乳癌(breast cancer) 初発症状(initial symptom) 貧血(anemia) 骨髄転移(bone marrow metastasis)
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 31
End Page 34
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.31
Title Alternative Evaluation of a one-step nucleic acid amplification (OSNA) assay for sentinel lymph node metastases in early breast cancer
FullText URL 126_25.pdf
Author Mizoo, Taeko| Shien, Tadahiko| Ito, Maiko| Nogami, Tomohiro| Iwamoto, Takayuki| Motoki, Takayuki| Taira, Naruto| Matsuoka, Junji| Doihara, Hiroyoshi|
Abstract  Introduction: The one-step nucleic acid amplification (OSNA) assay is a new method to detect sentinel lymph node (SLN) metastases using cytokeratin 19 (CK19) mRNA in early breast cancer. Here we retrospectively analyzed the advantages and disadvantages of the OSNA assay.  Methods: In a trial period, SLNs were divided into two sections, and we examined one side using the OSNA assay. The other side was examined by pathologists. After this period, we examined whole SLNs using only the OSNA assay. The patients with positive nodes by OSNA assay and/or pathology required axillary dissection.  Results: We examined 27 primary breast cancer patients (36 SLNs) during the trial period. The overall concordance rate between the OSNA assay and pathology results was 91%. In the later period, 157 patients (217 SLNs) were examined. The CK19-positive rate obtained by the OSNA assay was 16.5% (macrometastases OSNA (++) : 7.2%, micrometastases OSNA (+) : 9.2%). The non-SLN positive rate among the CK19-positivecases was 23%. The OSNA assay's false negative was one case in which the expression of CK-19 on the primary tumor and lymph node was not detected.  Conclusions: Our OSNA assay results were comparable to those obtained using a conventional pathological technique. Pathologists and laboratory technicians could save time and effort by using the OSNA assay when seeking the precise diagnosis during surgery.
Keywords OSNA法(OSNA method) センチネルリンパ節(sentinel lymph node) micrometastases CK-19
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 25
End Page 30
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.25
Title Alternative Concept and management of pancreaticobiliary maljunction
FullText URL 126_17.pdf
Author Noda, Takuo|
Keywords 膵・胆管合流異常 先天性胆道拡張症 分流手術胆道癌
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 17
End Page 24
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.17
Title Alternative A preoperative SUVmax greater than the ADCmin of the primary tumour : A predictor of disease recurrence and survival in patients with endometrial cancer
FullText URL 126_11.pdf
Author Nakamura, Keiichiro| Joja, Ikuo| Fukushima, Chikako| Haruma, Tomoko| Hayashi, Chiaki| Kusumoto, Tomoyuki| Seki, Noriko| Hongo, Atsushi| Hiramatsu, Yuji|
Keywords endometrial cancer SUVmax PET/CT predictor of poor prognosis
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 11
End Page 15
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.11
Title Alternative The mechanical stimulation of cells in 3D culture within a self-assembling peptide hydrogel
FullText URL 126_7.pdf
Author Nagai, Yusuke| Yokoi, Hidenori| Kaihara, Keiko| Naruse, Keiji|
Keywords 機械刺激 メカノバイオロジー 自己集合性ペプチド 3次元培養 スキャフォールド
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 7
End Page 10
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.7
Title Alternative Cholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophages
FullText URL 126_1.pdf
Author Miyamoto, Satoshi| Shikata, Kenichi| Miyasaka, Kyoko| Okada, Shinichi| Sasaki, Motofumi| Kodera, Ryo| Hirota, Daisho| Kajitani, Nobuo| Takatsuka, Tetsuharu| Kataoka Usui, Hitomi| Nishishita, Shingo| Horiguchi Sato, Chikage| Funakoshi, Akihiro| Nishimori, Hisakazu| Uchida, Haruhito Adam| Ogawa, Daisuke| Makino, Hirofumi|
Keywords cholecystokinin 糖尿病性腎症 抗炎症作用 腎保護効果
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 1
End Page 6
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.1