Title Alternative Reactivity of secretory immunoglobulin A against gut bacteria is attenuated by high-fat diet consumption
FullText URL poalas_035_009_011.pdf
Author Tsuruta, Takeshi| MUHOMAH, Teresia Aluoch| Sonoyama, Kei| Nishino, Naoki|
Abstract Secretory immunoglobulin A (SIgA) is predominant antibody secreted into the gut relating to maintain gut homeostasis. In the present study, we focused on the SIgA coating of gut bacteria as a mucosal immune response affecting the gut bacteria following a high-fat diet (HFD). This study newly showed that the level of SIgA coating of gut bacteria was significantly decreased in HFD-fed mice than normal-fat diet (NFD)-fed mice. Furthermore, we found that the relative abundances of gut bacteria were significantly negatively or positively correlated with the level of SIgA coating of gut bacteria in NFD-fed and HFD-fed mice. Our observations suggest that a decrease in the level of SIgA coating of the gut bacteria through a HFD might relate to HFD-induced changes in bacterial composition.
Publication Title Proceedings of Okayama Association for Laboratory Animal Science
Published Date 2019-06
Volume volume35
Start Page 9
End Page 11
language 日本語
File Version publisher
Author Gofuku, Akio|
Keywords operator support system information display model simplification cognitive state
Note 3rd International Conference on Nuclear Energy Technologies and Sciences (ICoNETS)<br/> Padang, INDONESIA<br/> SEP 19, 2019<br/> This fulltext is available in Dec 2020|
Published Date 2019-12-10
Publication Title AIP Conference Proceedings
Volume volume2180
Publisher AIP Publishing
Start Page 020028
ISSN 0094-243X
NCID AA00502977
Content Type Conference Paper
language 英語
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.1063/1.5135537
Web of Science KeyUT 000521828700028
Related Url isVersionOf https://doi.org/10.1063/1.5135537