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ID 15298
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Title Alternative
ステロイド依存性重症難治性喘息に対する複合温泉療法の作用機序
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Author
Tanizaki, Yoshiro
Kitani, Hikaru
Okazaki, Morihiro
Mifune, Takashi
Mitsunobu, Fumihiro Kaken ID publons researchmap
Takatori, Akimasa
Okuda, Hiroyuki
Ochi, Koji
Harada, Hideo
Kimura, Ikuro
Abstract
Effects of complex spa therapy, which comprises swimming training in a hot spring pool, inhalation of iodine salt solution and fango therapy, were analyzed in patients with steroid-dependent intractable asthma (SDIA) by comparison between the subjects with and without efficacy of the therapy. 1. The complex spa therapy was effective in the patients with lower levels of FEV(1.0%) and % PEFR. 2. The complex spa therapy was not always effective in the patients with a low value of % V(25), which represents depressed airflow in the small airways. 3. The efficacy of the complex spa therapy was found in the patients showing a low value of % V(25) accompanied by BAL neutrophilia, but not found in those without increased proportion (more than 10% ) of neutrophils in BAL fluid. The results reveal that the complex spa therapy is effective in patients with SDIA showing low values of FEV(1.0%) and % PEFR, and in those with a low value of % V(25) and BAL neutrophilia.
Abstract Alternative
ステロイド依存性重症難治性喘息を対象に,温泉プール水泳訓練,ヨードゾル吸入療法.鉱泥湿布療法からなる複合温泉療法の臨床効果の解析を行った。1.複合温泉療法は,FEV(1.0%)および% PEFR値の低い症例により有効であった。2.複合温泉療法は、細気管支領域の換気障害を示すと考えられる% V(25)値が低い症例に対して,必ずしも有効ではなかった。3.複合温泉療法の効果は,BAL液中好中球増多(10%以上)が見られ、かつ% V(25)値が低い症例により有効であったが、同様に% V(25)値が低くても,BAL液中に好中球増多 が見られない症例に対しては,有効ではなかった。以上の結果より,複合温泉療法はFEV(1.0%)や% PEFR値の低く,またBAL液中好中球増多が見られ,かつ% V(25)値が低いようなステロイド依存性重症難治性喘息に対して有効性が高いことが示唆された。
Keywords
complex spa therapy (複合温泉療法)
ventilatory function (換気機能)
BAL neutrophilia (BAL好中球増多)
bronchial asthma (気管支喘息)
Publication Title
岡大三朝分院研究報告
Published Date
1992-06
Volume
volume63
Publisher
岡山大学医学部附属病院三朝分院
Publisher Alternative
Misasa Medical Branch, Okayama University Medical School
Start Page
1
End Page
6
ISSN
0913-3771
NCID
AN10430852
Content Type
Departmental Bulletin Paper
OAI-PMH Set
岡山大学
language
英語
File Version
publisher
NAID
Eprints Journal Name
mmc