JaLCDOI 10.18926/11925
Title Alternative Effect of ferrous iron on 3T3-cell survival in cell culture
FullText URL 005_091_094.pdf
Author Yamamoto, Goki|
Abstract 細胞培養レベルでの二価鉄の影響をマウス3T3細胞を用いてコロニー法でみた結果は、細胞播種直後の二価鉄添加(濃度0.5mMで0.75%の生存率)と培地に二価鉄添加後の細胞播種(濃度0.5mMで55%の生存率)で異なった細胞生存率が得られたことから、いずれも単細胞処理後の浮遊細胞に対する影響と考慮して、ディシュ面への接着後の培養細胞に対する二価鉄の影響を検討した。細胞播種1日後の二価鉄添加では濃度0.5mMで73%の生存率が得られ、上記条件下よりも高率の生存率が認められた。さらに生存の細胞コロニーの径は処理群で短縮がみられ、増殖阻害が明らかに認められた。細胞播種直後の二価鉄添加の生存率曲線から得られた損傷回復が影響されない最低濃度0.25mMでの二価鉄の時間的処理では、1時間処理では統計的に有意差は認められなかったが、3時間、6時間処理で有意差の増殖阻害が認められた。
Abstract Alternative Previous reports demonstrated that adding ferrous iron into the culture medium immediately after seeding of cells showed significantly cell killing activity (0.75% survival by 0.5mM ferrous iron) than the case of the cell seeding after adding ferrous iron. In this report, the effect of an addition of ferrous iron after the adhesion of cells onto the dish, in the condition 1 day after cell seeding, was investigated by the colony method. The dose responsed survival curve obtained above condition showed nealy survival curve in the case of the cell seeding after addition of ferrous iron, and 72.9% survival by 0.5mM ferrou iron was estimated. But the colony diameter was shortened depending on the Fe(2+) doses, the 0.5mM-affected colony showed a half of the diameter of control colony, namely proliferation of the cells was inhibited. The 1 hour treatment with ferrous iron (0.25mM) did not inhibited, but both the 3 and 6 hours treatments inhibited significantly a proliferation of the cells checked by the diameter of colony. The facts suggest that both the oxidation mechanism of ferrous iron, induced radicals, promptly occured at the time of an addition of ferrous iron into the culture medium and the followed oxido-reductive reactions are concerned in the injury of cells.
Keywords 二価鉄 (ferrous iron) 細胞生存率 (cell survival)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 91
End Page 94
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313672
JaLCDOI 10.18926/11924
Title Alternative Development of thermosensitive polymer-conjugated enzyme for repeated use.
FullText URL 005_087_090.pdf
Author Mori, Shuji| Endo, Hiroshi|
Abstract 温度感受性ポリマー誘導体を作製し、アルカリホスファターゼ(ALP)と結合させることによって、反復利用が可能なALPの開発を試みた。温度感受性ポリマー結合ALPは、反応混合液の温度を37℃以上に温度を上げることによって、簡単に他の成分から分離回収することができ、回収後も約80%の活性を保持していることが明かとなった。
Abstract Alternative For the purpose of repeated use of enzyme, alkaline phoshatase congugated with the reactive derivative of thermosensitive polymer was developed. This novel enzyme was precipitated immediately and recovered from reaction mixture, when the solution temperature was raised to 37℃. Recovered enzyme retained 80% activity compared to that of untreated one.
Keywords 温度感受性ポリマー (thermosensitive polymer) 反復利用 (repeated use) アルカリホスファターゼ (alkaline phosphatase)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 87
End Page 90
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313551
JaLCDOI 10.18926/11918
Title Alternative リウマチ因子陽性ヒト血清中の免疫グロブリンGクラスリウマチ因子と免疫複合体ならびにCRPとの相関性
FullText URL 005_071_077.pdf
Author Tohge, Hiroko| Ichimura, Mitsuko| Sakiyama, Junko| Mori, Shuji| Nakata, Yasunari| Endo, Hiroshi|
Abstract We measured the concentration of three immunoglobulin classes of rheumatoid factors (Ig-RFs), C3d binding IgG immune complex (C3d-IC), C1q binding IgG immune complex (C1q-IC) and C-reactive protein (CRP) in 74 samples of human sera with high levels of RF (24.0~2350.0IU/ml). In sera with high levels of C3d-IC (>15.0μg/ml), there was a positive correlation between the levels of CRP and the IgG-RF, but there was no correlation between the levels of CRP and the immune complexes (C3d-IC and C1q-IC). And then, there was a positive correlation between the levels of CRP and IgG-RF or C3d-IC and IgG-RF when the levels of C1q-IC in patients sera were higher than 80.0μg/ml. However, there was no correlation between the levels of CRP and C1q-IC in these patients sera containing high levels of both C3d-IC and C1q-IC. These results indicated that the determination of C3d-IC, C1q-IC, IgG-RF and CRP in human sera containing RF denote different implications as inflammatory indexes on progression of rheumatoid arthritis and other autoimmune diseases.
Abstract Alternative 一般に慢性関節リウマチの診断ならびに活動性の一指標として、日常臨床検査では患者血清中のリウマチ因子の測定が実施されている。本論文ではRF検査依頼が有り、高RF値(24.0~2350.0IU/ml)を示した患者血清74検体について、免疫グロブリンクラス別RF値を測定するとともに自己IgGと補体との免疫複合体(IC)であるC1q-IgG・IC(C1q-IC)、C3d-IgG・IC(C3d-IC)ならびにCRP値を測定し、それらの測定値間の相関性について統計学的検討を行った。C3d-IC値が15.0μg/ml以上の高値を示す患者血清では、CRP値とIgGクラスのRF(IgG-RF)値間については正の相関結果がが得られた。また、C1q-IC値が80.0μg/ml以上の場合にもCRP値とIgG-RF値間およびC3d-IC値とIgG-RF値間では正の相関結果が得られた。しかし、C3d-ICならびにC1q-ICともに高値例の患者血清中のCRP値とC1q-IC値間には有意な相関は観察されなかった。以上の結果より、慢性関節リウマチの活動度を判定する上で、従来から炎症マーカーとしてCRP値が利用されているが、血清中に免疫複合体が高レベルに検出される患者については、炎症の指標としてCRP以外にもC1q-ICやC3d-ICおよびIgG-RF等を加えた総合的な判断が必要であることが示唆される。
Keywords self-associating IgG rheumatoid factor (自己IgG結合性リウマチ因子) C1q binding IgG immune complex (C1q結合IgG免疫複合体) C3d binding IgG immune complex (C3d結合IgG免疫複合体) C-reactive protein (C反応性タンパク質(CRP))
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 71
End Page 77
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313402
JaLCDOI 10.18926/11916
Title Alternative Life-long integrated sports
FullText URL 005_053_063.pdf
Author Jin, Fumio|
Abstract 行政機関による生涯スポーツの推進は、それなりに容認されよう。しかしながら、国民のすべてが、こぞってそれに応えているとしたら、異常である。元来、スポーツは、国民の一人ひとりが、気ままに営むべきものである。それを、スポーツ振興法等に名を借りて、スポーツの機会や条件を提供し、また、国民の健康や体力の増強に与って効力があるからといって、国や地方公共団体の管理に供するということへの、懸念が生じてくる。さらに、関係団体との接触についても懸念がある。巷間、伝わるところの”モスクワ五輪大会への干渉”である。具体的に知る由もないが、結論に至までの過程に重要な要素が含まれていたように思われる。今後も、生涯スポーツの関係団体等に対して、これと類似したケースが生じないとは限らない。公権力の介入も、充分に予想し得る。以下に、生涯スポーツ事業の系譜を纏め、対応への資料として、提供する。
Abstract Alternative The promotion of life-long integrated sports by goverment administration may be acceptable, However, it would be unusual if all citizens accepted this policy by the goverment. Essentially, sports should be played, by the independent will of each person. State and local goverments, may offer people the opportunity and conditions, under the sports Promotion Law, to play sports. Their reason for encouraging people to play sports is obviously because it promotes health and physical fitness. However, this policy may also create the fear that the authorities will control people. I am also anxious about contact between Japanese sports organizations and the goverment. To cite an example, the Japanese goverment interfered, and was, I believe, responsible for the non-participation of Japanese representatives as the Moscow Olympics. I am sure that this decision was affected by the goverment. We cannot guarantee that similar situations involving various sports group. It is possible that this sort of thing will occur again ; that the authorities will intervene in sporting activities. I would like to offer an organization chart regarding life-long integrated sports as follows ; (1) Beginning-after the war. (2) An origin. (3) Adult education. (4) Pre-Olympic-games. (5) Post-Olympic-games.
Keywords スポーツ (sports) 生涯教育 (life-long integrated education) 行政 (administration)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 53
End Page 63
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313597
JaLCDOI 10.18926/11914
Title Alternative The ideas about nursing course of senior high school teachers.
FullText URL 005_047_052.pdf
Author Takabatake, Harumi| Maeda, Makiko| Ohta, Takeo| Kitajima, Kouichi| Kondo, Masuko|
Abstract 近年、4年制大学の増設をはじめとした看護課程における教育の変革が進められつつある。これは質の高い看護の人材を必要とする社会のニーズに応えたものである。著者らはこれらの看護課程に対する意見を、岡山県下の高校で進路指導をしている教師に尋ね、郵送による質問紙法を用いて33名の回答を得た。その結果、以下のことが分かった。1. 51.5%の教師は、看護大学が増えると進学希望者の関心は呼ぶとしており、36.4%は、学生数の一定の増加があるだろうとしている。また、36.4%は教師の立場から看護課程への進学を勧めやすくなると考えている。2. 高校の教師は看護婦不足の理由として労働条件の厳しさを指摘している。3. 高校教師は進路として看護課程を勧める理由を仕事の専門性と奉仕性を多くあげていた。これらは、高等教育化と看護職のイメージの改善の両方が必要であることを示唆している。
Abstract Alternative Currently, improvement of nursing curriculum has been done in Japan, including the establishment of a four year course at universitiy, responding to the social needs for man-power for high quality nursing. A questionnaire survey by mail was done in 1993, to get ideas about the nursing course of high school teachers giving advice to students wishing to go on to university or college. Thirty three high school teachers out of a total of 76 schools in Okayama prefecture responded. The results were as follows; 1, Seventeen teachers (51.5%) answered that the increase of a four year course at university would be an incentive to students. Twelve teachers (36.4%) said that it might increase the number of students choosing the course. And also 12 teachers (36.4%) thought that they could recommend this course to students more easily than before. 2, They pointed out the harsh working conditions as the reason for a shortage of nursing manpower. 3, Their reasons why they recommend the nursing course to students were firstly the specialty and secondly devotion to people.
Keywords 看護婦イメージ 看護教育 (Nursing education) 高校教師 (Teachers of senior high school) Nursing carriculum
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 47
End Page 52
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313898
JaLCDOI 10.18926/11912
Title Alternative Images of nurses by senior high school students wishing to go on to the nursing course
FullText URL 005_037_045.pdf
Author Maeda, Makiko| Takabatake, Harumi| Kondo, Masuko| Ohta, Takeo| Kitajima, Koichi|
Abstract 本研究では、看護課程志望の高校生が看護職に対してどのようなイメージを持っているのか、看護教育機関の希望や将来の看護職種の希望は看護職に対するイメージと関係があるのかを明らかにしたいと考えた。岡山県下の全ての高校に在学中の看護課程志望高校生に対して、質問紙調査をおこなった。222名から回答が得られ、分析を行った結果、以下のことが明らかになった。1)看護課程志望高校生は看護職に対して非常に良いイメージを持っており、同時に労働条件の厳しさも理解していた。その良いイメージとは、看護職の持つ尊さや献身性に由来する自負心と、資格のもつ現実的利点であった。しかし、看護職の専門性を表す、高度な知識・判断・技術、生涯教育の必要性の認識は低かった。2)短大・大学を志望する高校生は、看護学校・准看護学校志望者に比べ、看護職は生涯教育を必要とするとイメージしていた。3)看護婦、保健婦、助産婦のどの職種を希望するかによって、看護職に対するイメージに違いがあった。
Abstract Alternative A qusetionnaire survey was done by senior high school students wishing to go on to the nursing course in Okayama Prefecture, to know what images of nurses they had, what course for nursing education they wished to best for and what they would like nursing profession to be. Results of analysing data obtained from 222 students were as follows; 1. They had favorable images of nurses in high rates, although they also recognized the harsh working conditions. Those images were thought to be derived from the preciousness of nursing, devotion to people, and advantage of the license. But recognition of specialty of nursing indicated by items such as knowledge, judgement, skill and continuing education was low. 2. Necessity of continuing education was recognized by students wishing to go on to university or junior college better than students of vocational school of registered and assistant nurses. 3. Images of nurses were different by their choice of profession such as clinical nurses, public health nurses and midwives which they would like to be in the future.
Keywords 看護職に対するイメージ (images of nurses) 高校生 (senior high school students) 看護課程 (nursing course) 看護職種 (nursing profession)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 37
End Page 45
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313845
JaLCDOI 10.18926/11904
Title Alternative A Study of community nursing Practice of basic nursing educaition curriculum - Analysis of practice repord by student nurses -
FullText URL 005_009_015.pdf
Author Ono, Tsuruko| Ohta, Takeo| Maeda, Makiko| Takabatake, Harumi|
Abstract 地域看護実習は、地域における看護の役割を理解することを主なねらいとして、保健所で実習を行っているが、保健所実習が地域看護実習の目標を達成しているかは否かを、学生の実習記録を分析し検討した。80%以上の学生が体験している実習内容は、家庭訪問、集団検診、共同作業所、健康相談等である。実習目標の記載状況は「実習項目別実習記録」及び実習全体のまとめ「総括」の記載内容から抽出し分析した。目標記載率70%以上であった実習項目は、実習目標①(地域の人々の生活及び健康問題の理解)は共同作業所、グループ指導、家庭訪問であり、目標②(保健サービスの実態の理解)では家庭訪問であった。また「総括」では目標②の記載率が高く、目標③(地域の看護活動の実態を学ぶ)の記載率67%と予測に反して高くなかった。今後地域看護、継続看護に関する講義のあり方を含めて、地域看護実習の位置づけを再検討する必要がある。
Abstract Alternative Practice reports at the health center for 1 week written by 152 student nurses were analysed to know wether they achieved their goal of the course for community nursing or not. More than 80% students attended at home visits, mass health examination, common workshops for mentally disordered persons and health counsclling. Practice for understanding peoples'lives and health problems in the community were well achieved in practice at the common workshop, group guidance and home visit. They understood about health care and servicesin the community through home visits. Their comprehension of role of the community nursing was not so sufficient as expected for mark of curriculum.
Keywords 地域看護実習 (community nursing practice) 保健所実習 (practice at public health center) 実習目標 (goal of the course for community nursing) 看護基礎教育課程 (basic narsing education curriculum)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1995-01-31
Volume volume5
Start Page 9
End Page 15
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313788
JaLCDOI 10.18926/11893
Title Alternative Daily VMA (vanillyl mandelic acid) variation in urine in relation of fatigue sensation, stress and life stile of nurses on night shift.
FullText URL 004_105_110.pdf
Author Inoshita, Hikari| Ouchi, Takeshi| Ninomiya, Tsuneo|
Abstract Daily VMA variation in urine in relation of fatigue sensation, stress and life stile of nurses on night shift. To evaluate exhaustion objectively in hospital nurses, daily variation of urinaly VMA (vanillyl mandelic acid) excretion was measured in hospital nurses working in daytime and nighttime and it's correlation with the data from Psychological Stress Response Scale (PSRS) test, the burn-out scale, quality and quantity of sleep and daily life stile recorded throughout 24 hours were studied. VMA level in urine showed circadian rhythmic movement, higher in daytime and lower in nighttime. During night shift, VMA in urine in nighttime showed slightly higher level than during day shift but in the subsequent daytime after night shift, VMA level was stillkeeping normal circadian rhythm, resuling flatness of daily fluctuation of VMA level. Dissatisfaction of sleep during daily fluctation of VMA level. Dissatisfaction of sleep during daytime was noticed. Correlation between VMA level in urine and sense of tiredness, stresses or burn-out scale were not carfied in this study because of shortage of samples but working conditions might affect biologicalresponse of exhaustion.
Keywords VMAの変動 三交替性疲労感 ストレス 生活時間
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 105
End Page 110
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313516
JaLCDOI 10.18926/11891
Title Alternative Sutdies on Galvanic skin responce (GSR) in relation to psychological condition test for the students.
FullText URL 004_099_103.pdf
Author Inoshita, Hikari| Ogata, Michiko| Tokunaga, Ayumi| Bando, Mika| Yamada, Yoko| Marumoto, Kazumi|
Abstract Psychological anxiety trend was studied by Galvanic skin responce (GSR) 60 students, 7 of male and 53 of female, in School of Health Sciences Tokushima University, and the results were compared with the data from State Anxiety Inventory (STAI) test and Self-rating Depression Scale (SDS) test. Compared GSR with STAI, initial responses of GSR showed postive relation to state anxiety in STAI test ; while compared GSR with SDS, both of spontaneous and initial responses showed reversed correlation. Although spontaneous and initial responce in GSR were more remarkably augmented in the female students than male students, these trends might not be caused only by sex difference because the test environment was not same in two groups. Based on these data, GSR is considered to represent objective indicator of psychological anxiety. However further basic data accumulations are needed in regard to some factors affecting the data such as sex of examiners or examinees and test environment.
Keywords 皮膚電気反射(GSR) 大学生 心理状態 不安尺度 抑うつ尺度
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 99
End Page 103
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313732
JaLCDOI 10.18926/11889
Title Alternative A practice for nursing students to understand a patient through his book of struggling against disabilities due to cervical injury
FullText URL 004_089_097.pdf
Author Ohta, Niwa| Furumai, Terue|
Abstract Thirty-nine nursing students in their third year were required to read a book written by a male patient struggling against disabilities due to cervical injury for nine years in the hospital and to report their impressions during their clinical practice. The contents of their reports were classified to four categories, that is understanding, helping care, nursing attitude for the patients and problems for the students themselves. The most frequent descriptions were made about understanding the patients, especially about his affliction caused by psychological feeling of his handicaps. The subsequent frequent descriptions were concerning the care of the patients such as importance to improve his residual function and necessity of team work care for the purpose. Doscriptions about nursing attitude were followed. This method was helpful for understanding the situation of a patient and for practicing nursing processes to respond to the patient's needs.
Keywords 身体障害 闘病記 患者理解
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 89
End Page 97
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313994
JaLCDOI 10.18926/11875
Title Alternative Ferrous Iron-induced Lipid Peroxidation in Cell Culture: Effects of Ferrous and Ferric Irons on Cell Survival and Serum Lipid Peroxide
FullText URL 004_061_068.pdf
Author Yamamoto, Goki|
Abstract Cell killing activities of ferrous and ferric irons (Fe(2+), Fe(3+)) in cultured 3T3 cells were investigated by the colony forming method in the culture medium containing 10% calf serum. In the colony forming method, small isolated colonies are seen in the dish which are the resulted of individual cells having undergone a series of cell divisions. Survival curve for Fe(2+)-induced loss of reproductive capacity (cell death) in 3T3 cells, showed a shoulder at low concentrations and only became exponential at high concentrations. Cells affected at 0.05mM Fe(2+) underwent apparently normal cell divisions, but at a much slower rate than the control. Survival rate at 0.5mM Fe(2+), which iron was added after seeding cells (added group), showed 0.75% but that at 0.5mM Fe(3+) did 19.3%. From the determination of Fe(2+) content carried out by the colorimetric method used N-PSAP, the oxidation of Fe(2+) was seen rapidly after adding Fe(2+) into the culture medium. In the cases of cells seeded 3 hours after adding Fe(2+) or Fe(3+) (preadded group), the survival rates showed much lower than those of the added groups, that is 55% at 0.5mM Fe(2+) and 89% at 0.5mM Fe(3+). The facts suggest that the radical reactions iniciated by the oxidation of Fe(2+) under the presence of cells, occured just after adding Fe(2+), play a crucial role in the damages on the adhesion of cells onto the dish and the following proliferation of cells. Serum lipid peroxides, as thiobarbituric acid reactive substances (TBA value), of the final cultured medium at colony counting time were measured. In the Fe(2+) added group, the TBA values more increased in proportion to the added concentrations of Fe(2+), whereas in the Fe(3+) added group, the increments of TBA values were very slightly and not to be depended on the concentrations. Furthermore, the TBA values of the Fe(2+) or Fe(3+) preadded groups were estimated as well as those of the added groups, respectively. The facts suggest that serum lipid peroxides induced by Fe(2+) have little effect on the proliferation capacity of cells in the level of cell culture.
Keywords Cell Survival Ferrous and Ferric Irons Serum Lipid Peroxide
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 61
End Page 68
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313910
JaLCDOI 10.18926/11873
Title Alternative Clearance study of polyethylene glycol-modified cholesterol esterase.
FullText URL 004_053_055.pdf
Author Mori, Shuji| Nakata, Yasunari| Endo, Hiroshi|
Abstract The clearance of polyethylene glycol-modified cholesterol esterase was investigated spectrophotometrically, as compared with native one. PEG-modification provided the significant elongation in clearance time of cholesterol esterase after intravenous injection in mouse. This method was shown to be effective for creating new biomaterials.
Keywords cholesterol esterase polyethylene glycol modification in vivo clearance
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 53
End Page 55
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313810
JaLCDOI 10.18926/11871
Title Alternative IgG Heavy-Chain Subclass Typing of Human Serum M-Protein -Optimal condition for the separation and the detection with high resolution of agarose gel isoelectrofocusing-
FullText URL 004_047_051.pdf
Author Ichimura, Mitsuko| Tohge, Hiroko| Sakiyama, Junko| Nakata, Yasunari| Endo, Hiroshi|
Abstract IgG Heavy-Chain subclass typing of human serum M-protein were isoelectrofocussed (IEF) in agarose gel, and then the bands of IgG were detected with peroxidase-conjugated anti-human IgG1-4 monoclonal antibodies on the same isoelectrofocussed agarose gel plate. This IEF enzyme immunodetection patterns were composed of four to eight discrete bands (The range of pI was 6.0 to 9.0). These bands were dependent on immunofixationbands. It was very specific and clear to detect the subclass of IgG Type M-protein in human serum using this method.
Keywords IgG Subclass M-Protein Isoelectrofocusing Monoclonal Antibodies
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 47
End Page 51
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313808
JaLCDOI 10.18926/11867
Title Alternative Reactivity and stability of propentdyopent produced by the oxidative cleavage of hemin
FullText URL 004_031_036.pdf
Author Hirota, Kazuhiro|
Abstract The water adduct of propentdyopent, which have two propionic acid groups and two methyl groups on two pyrrole rings and a hydroxyl group at the valley position, was prepared by the oxidation of hemin with hydrogen peroxide. Esterification of the two propionic acid groups and substitution of alkoxy group for the hydroxy group were studied to examine the reactivity of the adduct. The esterification took place with the substitution of methoxy group on treatment with a solution of 2% sulfuric acid in methanol at 60℃. The substitutions of methoxy and ethoxy groups were attained without any esterification on treatment with a solution 10% acetic in methanol at 80℃ and a solution of 10% acetic acid in ethanol, respectively. Only esterification was performed on treatment with an ethereal solution of diazomethane. Hydrolysis of the ester occurred simultaneously with the substitution of hydroxyl group for methoxy group on standing with 0.5N hydrochloric acid at room temperature. Those compounds were purified by thin-layer chromatography and identified with mass and nmr spectra.
Keywords Propentdyopent pentdyopent hemin oxidation dipyrrole
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 31
End Page 36
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313897
JaLCDOI 10.18926/11864
Title Alternative The first case of hairworm, Gordius sp. vomited from a domestic dog in Japan
FullText URL 004_023_025.pdf
Author Shimoe, Toshimitsu| Hashiguchi, Masahiro| Saito, Tetsuro| Morishige, Kazuhisa| Tongu, Yasumasa|
Abstract An adult female hairworm was vomited from a domestic dog with a cough in Hiroshima Prefecture. The worm body was long and slender, measuring 42.5 cm in length and 1 mm in maximum width. The specimen showed microscopically the smooth cuticular without tuberculations. This case is the first record of Gordius sp. infection in a dog in Japan.
Keywords Gordius hairworm dog
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 23
End Page 25
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313799
JaLCDOI 10.18926/11862
Title Alternative A case of Mesocestoides sp. infection in a domestic cat
FullText URL 004_019_021.pdf
Author Saito, Tetsuro| Morishige, Kazuhisa| Tongu, Yasumasa|
Abstract A 2-year-old domestic cat discharged 2 small cestode segments (1mm × 1mm) into the stool on 16th in March, 1993. On the next day, 4 cestode strobilae without scolex were obtained from this cat by administration of praziquantel (30mg/kg). Strobilae measured approximately 60-86mm in length and 1mm in maximum width. In each immature segment, the number of testes was more than 60. A paruterus measuring 316-473μm × 316-371μm was situated at the rear central part of each gravid segment. The eggs (32 × 24μm) in the paruterus contained oncosphers. These Mesocestoides Cestoda were not identified as M.lineatus or M. literatus for lack of their scoleces.
Keywords Mesocestoides sp. domestic cat Fukuyama City
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1994-01-31
Volume volume4
Start Page 19
End Page 21
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313812
JaLCDOI 10.18926/11849
Title Alternative Physical Image Quality of Rapid Processing Films
FullText URL 003_099_104.pdf
Author Yoshida, Akira| Honda, Mitsugi| Nakamura, Nobue| Arioka, Tadashi| Kobashi, Toshimi| Takeuchi, Tomoyuki| Mikami, Yasutaka| Sugita, Katsuhiko| Hiraki, Yoshio|
Abstract The imaging properties of Konica "new" SR series films and "old" MG-SR series films for rapid processing were measured in combination with green-emitting intensifying screens. The measured image quality prarameters include: characteristic curve, modulation transfer function (MTF) and Wiener spectrum. The relative speeds of the new SR series systems were slower than those of the old MG-SR series systems from 10 to 25%. The MTF's of the new systems were generally comparable to those of the old systems, except that SR-G system was improved with an increase of approximately 10%. In the Wiener spectrum measurement, however, the new systems showed from 10 to 35% decrease in low-frequency noise.
Keywords Rapid Processing Films Image Quality Characteristic Curve MTF Wiener Spectrum
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1993-01-31
Volume volume3
Start Page 99
End Page 104
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002314046
JaLCDOI 10.18926/11847
Title Alternative The results of liver function test on workers handling ethanol and isopropanol solvents
FullText URL 003_093_097.pdf
Author Ohta, Takeo| Endo, Hiroshi| Mori, Shuji| Koda, Shigeki| Oze, Yutaka|
Abstract Liver function tests such as GOT, GPT, γ-GTP and ornithine carbamyl transferase (OCT) were done on workers handling alcoholic solvents. One was a group of molders working in a foundry where they sprayed ethanol solvent on the surface of a sandbox and burnt it. Another was a group of painters at an iron and steel works and they sprayed paint with isopropanol solvent on iron and steel plates. No statistical differences in the results of tests between the solvent workers and control groups were seen. High correlations were found between GOT/γ-GTP and OCT/γ-GTP. OCT of 4 workers who had drunk alcohol on the day before test showed a statisically high value compared to workers who had not drunk alcohol.
Keywords Ethanol Isopropanol Liver Function Test アルコール系溶剤 肝機能
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1993-01-31
Volume volume3
Start Page 93
End Page 97
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313962
JaLCDOI 10.18926/11845
Title Alternative A Tendency of the Bacterial Food-Poisoning from 1981 to 1991
FullText URL 003_087_091.pdf
Author Akatsuka, Kazuya|
Abstract From the viewpoint of the tendency by the bacterial food-poisoning from 1981 to 1991, it seems that the tendency is not relatively changed in comparison with the data before 1981. However, a few changes are appeared in pathogenic substances, preparing facilities, and serving places, respectively. Namely, the tendency to be just little decrease of the incident rate of Vibrio parahaemolyticus and Staphylococcus aureus on pathogenic substances is appeared in 10 years. Furthermore, on the preparing facilities and serving places, it seems that restaurants and caterers are characterized by the increase of the incident rate of bacterial food poisonings togather with the increases of food service industries.
Keywords 食中毒 Vibrio parahaemolyticus Staphylococcus aureus Esherichia coli 魚介類
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1993-01-31
Volume volume3
Start Page 87
End Page 91
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313930
JaLCDOI 10.18926/11840
Title Alternative The Utopia of Western Mind and Experimental Science New Atlantis (F.Bacon, 1627)
FullText URL 003_067_074.pdf
Author Takeda, Terufumi|
Abstract TO THE READER by Bacon's secretary William Rawley when he published New Atlantis after Bacon's death is quoted here as a substitute for the synopsis of this paper : This Fable my Lord devised, to the end that he might exhibit therein, a model or description of a College, instituted for the interpreting of Nature, and the producing of great and marvellous works for the benefit of man ; under the name of Salomon's House, or the College of the Six Days' Works. And even so far his Lordship hath proceded, as to finish that part. Certainly, the model is more vast, and high, than can possibly be imitated in all things ; Notwithstanding most things therein are within men's power to effect・・・・
Keywords Renaissance Utopia Francis Bacon New Atlantis Experimental Science
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1993-01-31
Volume volume3
Start Page 67
End Page 74
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313706