Title Alternative The 50th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery
FullText URL 127_69.pdf
Author Sano, Shuji|
Publication Title 岡山医学会雑誌
Published Date 2015-04-01
Volume volume127
Issue issue1
Start Page 69
End Page 72
ISSN 0030-1558
language 日本語
Copyright Holders Copyright (c) 2015 岡山医学会
File Version publisher
DOI 10.4044/joma.127.69
NAID 130005068343
Author Kobayashi, Junko| Yoshida, Masashi| Tarui, Suguru| Hirata, Masataka| Nagai, Yusuke| Kasahara, Shingo| Naruse, Keiji| Ito, Hiroshi| Sano, Shunji| Oh, Hidemasa|
Published Date 2014-07-22
Publication Title PLoS ONE
Volume volume9
Issue issue7
Content Type Journal Article
Title Alternative The 16th Annual Meeting of Japanese Society for Adult Congenital Heart Disease
FullText URL 126_173.pdf
Author Sano, Shuji|
Publication Title 岡山医学会雑誌
Published Date 2014-08-01
Volume volume126
Issue issue2
Start Page 173
End Page 174
ISSN 0030-1558
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.173
NAID 120005468262
Author Kanamitsu, Hitoshi| Fujii, Yasuhiro| Mitsui, Hideya| Sano, Shunji|
Published Date 2013-07-04
Publication Title Artificial Organs
Volume volume37
Issue issue11
Content Type Journal Article
Author Ohno, Naoki| Ohtsuki, Shinichi| Kataoka, Koichi| Baba, Kenji| Okamoto, Yoshio| Kondo, Maiko| Sano, Shunji| Kasahara, Shingo| Honjo, Osami| Morishima, Tsuneo|
Published Date 2013-04
Publication Title Catheterization and Cardiovascular Interventions
Volume volume81
Issue issue5
Content Type Journal Article
Title Alternative Damus-Kaye-Stansel anastomosis
FullText URL 124_9.pdf
Author Fujii, Yasuhiro| Sano, Shunji| Arai, Sadahiko| Kasahara, Shingo| Tateishi, Atsushi| Takagaki, Masami| Fujita, Yasufumi| Ozawa, Susumu|
Keywords Damus-Kaye-Stansel吻合 単心室症 心室流出路狭窄 肺動脈弁逆流
Publication Title 岡山医学会雑誌
Published Date 2012-04-01
Volume volume124
Issue issue1
Start Page 9
End Page 13
ISSN 0030-1558
language 日本語
Copyright Holders Copyright (c) 2012 岡山医学会
File Version publisher
DOI 10.4044/joma.124.9
NAID 130004505753
JaLCDOI 10.18926/AMO/41325
FullText URL 64_6_391.pdf
Author Suezawa, Takanori| Ishino, Kozo| Honjo, Osami| Osaki, Satoru| Kotani, Yasuhiro| Sano, Shunji|
Abstract We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ventricle during aortic cross-clamping. This study was performed to determine the appropriate root pressure to maintain the heartbeat without causing deterioration of ventricular function. Study 1. Under partial CPB, the ascending aorta was cross-clamped in 6 pigs (group 1). Experimental data at various systolic aortic root pressures was analysed to determine the appropriate root pressure. Study 2. In group 2 (control, n=6), the aorta was not clamped, while in group 3 (n=6), the aorta was cross-clamped for 60 min and the systolic aortic root pressure was maintained at the pressure determined in study 1. Study 1. The diastolic coronary flow was stabilized at values comparable to that before initiation of CPB (6.6±1.4ml/beat) when the systolic aortic root pressure was above 80mmHg. Intracardiac pressure and the myocardial oxygen consumption (MvO2) seemed to be acceptable when the systolic aortic root pressure was below 100mmHg. Therefore, 90mmHg was selected for study 2. Study 2. Perioperative cardiac function did not differ between the groups. We concluded that 90mmHg was the systolic aortic root pressure appropriate for this method.
Keywords aortic cross-clamp coronary flow root pressure cardiopulmonary bypass arch repair
Amo Type Original Article
Published Date 2010-12
Publication Title Acta Medica Okayama
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 391
End Page 397
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173809
Web of Sience KeyUT 000285664200006
Author Sano, Shunji| Ishino, Kozo| Kawada, Masaaki| Yoshizumi, Ko| Takeuchi, Mamoru| Ohtsuki, Shin-ichi|
Published Date 2004-10
Publication Title Cardiology in the Young
Volume volume14
Content Type Journal Article
JaLCDOI 10.18926/AMO/32908
FullText URL fulltext.pdf
Author Fujii, Yasuhiro| Kasahara, Shingo| Kanki,, Kazushige| Mitsui, Hideya| Ishino, Kozo| Sano, Shunji|
Abstract <p>We describe a successful case of surgical treatment for anomalous left coronary artery from the pulmonary artery (ALCAPA) syndrome with severe left ventricular dysfunction. Because of the severe left ventricular dysfunction, we planned to use an extracorporeal membrane oxygenation for heart support until a satisfactory recovery had been established. The left ventricular function signifi cantly recovered in a few days, and the patient could be discharged without any complications.</p>
Keywords coronary circulation anomalous left coronary artery from the pulmonary artery extracorporeal circulation extracorporeal membrane oxygenation
Amo Type Case Report
Published Date 2007-02
Publication Title Acta Medica Okayama
Volume volume61
Issue issue1
Publisher Okayama University Medical School
Start Page 41
End Page 45
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 17332841
Web of Sience KeyUT 000244432400006
JaLCDOI 10.18926/AMO/32846
FullText URL fulltext.pdf
Author Mine, Yoshinari| Mitsui, Hideya| Oshima, Yu| Noishiki, Yasuharu| Nakai, Mikizo| Sano, Shunji|
Abstract <p>Our meticulous investigation of ePTFE graft breakage when a wire placed at the edge of an ePTFE graft was pulled, revealed that, depending on the breakage pattern, a break starts much earlier than the peak suture retention strength, which is the current international indicator for anastomotic-site break strength. Furthermore, the breakage patterns differ based on the thickness of the wire and the fiber direction of the ePTFE graft. Based on these findings, we advocate measuring the peak suture retention strength using 0.10-mm sutures and a standardized wire thickness in order to assess the anastomotic retention strength of ePTFE grafts.</p>
Keywords ePTFE suture retention strength anastomotic strength
Amo Type Original Article
Published Date 2010-04
Publication Title Acta Medica Okayama
Volume volume64
Issue issue2
Publisher Okayama University Medical School
Start Page 121
End Page 128
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 20424667
Web of Sience KeyUT 000276996900006
JaLCDOI 10.18926/AMO/32300
FullText URL fulltext.pdf
Author Nakamura, Koki| Irie, Hiroyuki| Fujisawa, Emi| Yoshioka, Hidekatsu| Ninomiya, Yoshifumi| Sakuma, Isao| Sano, Shunji|
Abstract <p>While heat shock protein (HSP) 72 is known as a stress protein, there have been no reports of HSP 72 expression in patients who have undergone surgery for congenital heart disease. Fourteen patients (7 males and 7 females) who had undergone surgery for congenital heart disease were studied. The ages of the patients ranged from 2 months to 43 years old (mean 6.5 +/- 10.8 years old; median 3.0 years old). The diagnoses were Tetralogy of Fallot in seven, pulmonary atresia with ventricular septal defect (VSD) in three, complex anomalies in three, and VSD in one patient. Histological study and HSP analysis using Western blots and immunostaining with anti-HSP 72 monoclonal antibody were performed for right ventricular muscle samples resected during the surgery. The histological findings showed hypertrophic changes of ventricular cardiomyocytes in all samples studied. Western blots detected HSP 72 expression of various degrees in all specimens. Immunostaining using monoclonal antibody against HSP 72 showed that the protein was present in the nuclei and cytoplasm of cardiomyocytes. In conclusion, although it is difficult to determine the cause of the &#34;stress&#34; that triggers HSP 72 expression in cardiomyocytes, low O2 saturation and pressure overload might act as a &#34;stress&#34;, and the only common factor that induced HSP 72 in every sample was hypertrophy.</p>
Keywords heat shock protein 72 (HSP 72) human heart congentional cardiac surgery hypertrophy
Amo Type Article
Published Date 2000-06
Publication Title Acta Medica Okayama
Volume volume54
Issue issue3
Publisher Okayama University Medical School
Start Page 103
End Page 109
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 10925734
Web of Sience KeyUT 000087965700002
JaLCDOI 10.18926/AMO/32016
FullText URL fulltext.pdf
Author Yasui, Kotaro| Kanazawa, Susumu| Mimura, Hidefumi| Dendo, Shuichi| Hiraki, Yoshio| Irie, Hiroyuki| Sano, Shunji|
Abstract <p>An 83-year-old man with a large internal iliac artery aneurysm (IIAA) was treated with the use of stent-graft, suggesting successful results at 3, 6, and 12 months after treatment. However, 24-month follow-up computed tomography showed minor peripheral opacification of the IIAA. The patient underwent surgical endoaneurysmorrhaphy. No previous report of long-term recanalization of a satisfactorily thrombosed iliac artery aneurysm at 2 years or more after stent-grafting has been previously reported. Further follow-up studies need to be performed on the present procedure before anyone can confidently recommend it in regard to its long-term safety.</p>
Keywords aneurysm iliac---stents and prosthesis
Amo Type Article
Published Date 2001-11
Publication Title Acta Medica Okayama
Volume volume55
Issue issue5
Publisher Okayama University Medical School
Start Page 315
End Page 318
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 11688956
Web of Sience KeyUT 000171635400009
JaLCDOI 10.18926/AMO/31981
FullText URL fulltext.pdf
Author Ohtsuki, Shinnichi| Baba, Kenji| Kataoka, Kohichi| Ohno, Naoki| Okamoto, Yoshio| Ishino, Kozo| Kawada, Masaaki| Sano, Shunji| Sato, Shuhei| Morishima, Tsuneo|
Abstract <p>We investigated the usefulness of helical computed tomography(CT)in the morphological diagnosis of pulmonary vein stenosis, particularly that in infants and small children. In total, 20 helical CT examinations were performed in 10 post-operative cases of Total Anomalous Pulmonary Venous Drainage(TAPVD), 3 cases of single right ventricle, and 1 case of single left ventricle. In all cases, distinct morphological imaging was possible. Pulmonary vein stenosis could be categorized into three types: (1)stenosis from the anastomosis of the common pulmonary vein (CPV)-the left atrium (LA) to the peripheral pulmonary vein; (2) stenosis only at the anastomosis of CPV-LA; and (3) stenosis due to compression by nearby organs. Coronal views by multiplanar reconstruction (MPR) provided morphological information along the up-down direction of the body axis. Morphological diagnosis of pulmonary vein stenosis is important in deciding prognosis and therapeutic regimens, and helical CT was considered useful for such diagnosis in our 14 young patients.</p>
Keywords pulmonary vein stenosis helical CT
Amo Type Article
Published Date 2005-06
Publication Title Acta Medica Okayama
Volume volume59
Issue issue3
Publisher Okayama University Medical School
Start Page 93
End Page 98
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 16049562
Web of Sience KeyUT 000230039100004
JaLCDOI 10.18926/AMO/31840
FullText URL fulltext.pdf
Author Fujita, Yasufumi| Ishino, Kozo| Nakanishi, Koji| Fujii, Yasuhiro| Kawada, Masaaki| Sano, Shunji|
Abstract <p>This study evaluated the effects of chronic hypoxia from birth on the resistance of rat hearts to global ischemia, with special emphasis on the duration of hypoxia. Male Wistar rats were housed from birth for 4 weeks or 8 weeks either in a hypoxic environment (FiO20.12) or in ambient air (8 animals for each group). Isolated rat hearts were perfused for 40 min with oxygenated Krebs-Henseleit buffer, subjected to 20 min global no-flow ischemia at 37, and then underwent 40 min of reperfusion. A non-elastic balloon was inserted into the left ventricle and inflated until the pre-ischemic LVEDP rose to 8mmHg. Cardiac function was measured before and after ischemia. The post-ischemic percent recovery of LVDP in hypoxic hearts was worse than in normoxic hearts (4 weeks:55+/-7 vs. 96+/-3%, p0.01;8 weeks:40+/-5 vs. 92+/-4%, p0.01), and was worst in the 8-week-hypoxic hearts. Similarly, the percent recovery of dP/dt in the hypoxic hearts was lower than in the normoxic hearts (4 weeks:51+/-5 vs. 96+/-7%, p0.01;8 weeks:31+/-6 vs. 92+/-7%, p0.01), and was lowest in the 8-week-hypoxic hearts. In conclusion, cyanotic myocardium revealed an age-dependent vulnerability to ischemia-reperfusion injury in a chronic hypoxic rat model.</p>
Keywords chronic hypoxia ischemia-reperfusion injury aging
Amo Type Original Article
Published Date 2009-10
Publication Title Acta Medica Okayama
Volume volume63
Issue issue5
Publisher Okayama University Medical School
Start Page 237
End Page 242
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 19893599
Web of Sience KeyUT 000271132000003
JaLCDOI 10.18926/AMO/31832
FullText URL fulltext.pdf
Author Itoh, Atsushi| Tomita, Hideshi| Sano, Shunji|
Abstract <p>Little information is available on the mechanism of diastolic left ventricular (LV) dysfunction in patients with chronic respiratory disease complicated by hypoxia. The purpose of this study was to investigate how chronic hypoxia impairs LV diastolic function in an hypoxic animal model. Thirty-six male Wistar rats 8 weeks old were assigned to normoxia (N), chronic hypoxia (CH), and re-normoxia (RN) groups, 12 rats per group. The N group rats were kept in ambient air for 8 weeks, while the CH group was kept hypoxic for 8 weeks. After 8 weeks of hypoxia the RN group rats were kept for a further 8 weeks in ambient air. LV systolic and diastolic functions, as well as right ventricular (RV) function, were analyzed using Doppler echocardiography;we also measured the hematocrit, and weighed the LV and RV. Hematocrit, RV weight/body weight, and RV weight/LV weight were higher in the CH group than in the other 2 groups. However, most of these parameters returned to normoxia levels after re-normoxia. In the CH group, LV dimension and area were smaller than in the other 2 groups. LV systolic function was preserved in all groups;however, in the CH group, mitral flow showed a restrictive pattern, while pulmonary flow demonstrated a pulmonary hypertensive pattern with prolonged RV ejection time. In conclusion, chronic hypoxia induced pulmonary hypertension and RV hypertrophy. Although LV systolic function was preserved, diastolic function was impaired in hypoxia. Ventricular interaction may impair LV diastolic function.</p>
Keywords chronic hypoxia left ventricular diastolic function pulmonary hypertension right ventricular hypertrophy ventricular interaction
Amo Type Original Article
Published Date 2009-04
Publication Title Acta Medica Okayama
Volume volume63
Issue issue2
Publisher Okayama University Medical School
Start Page 87
End Page 96
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 19404340
Web of Sience KeyUT 000265457600003
JaLCDOI 10.18926/AMO/31757
FullText URL fulltext.pdf
Author Sano, Shunji| Nawa, Sugato| Senoo, Yoshimasa| Teramoto, Shigeru|
Abstract <p>Thirty-eight patients were operated on for mitral stenosis between March 1979 and September 1981. Thirty-six of them were examined as to their age, symptom duration, chest roentgenograms, electrocardiograms and echocardiograms to obtain various indices of left ventricular function. The usefulness of these indices as preoperative risk factors for predicting postoperative low cardiac output syndrome (LOS) was investigated. Cases which had values of ejection fraction, cardiac index, percent fiber shortening or mean velocity of circumferential fiber shortening less than 0.45, 2.0 l/min/m2, 25% and 0.80 circ/sec, respectively, in the preoperative echocardiographic examination were associated with a greater chance of postoperative LOS. Each of these factors was independently useful as a risk factor in cardiac surgery for mitral stenosis. Moreover, it was revealed that the combination of a preoperative percent fractional shortening (%FS) of less than 30% and a cardiac index smaller than 2.0 l/min/m2 indicated a strong predisposition toward postoperative LOS.</p>
Keywords mitral stenosis low cardiac output syndrome risk factor echocardiography
Amo Type Article
Published Date 1987-10
Publication Title Acta Medica Okayama
Volume volume41
Issue issue5
Publisher Okayama University Medical School
Start Page 215
End Page 222
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 3687493
Web of Sience KeyUT A1987K590100005
JaLCDOI 10.18926/AMO/31314
FullText URL fulltext.pdf
Author Yunoki, Keiji| Uchida, Hatuzo| Sano, Shunji| Shimizu, Nobuyoshi|
Abstract <p>Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.</p>
Keywords stent-graft endoluminal graft acute aortic dissection Blanton’s methed
Amo Type Article
Published Date 1998-04
Publication Title Acta Medica Okayama
Volume volume52
Issue issue2
Publisher Okayama University Medical School
Start Page 89
End Page 95
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 9588224
Web of Sience KeyUT 000073363000004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/6434
JaLCDOI 10.18926/AMO/31313
FullText URL fulltext.pdf
Author Fujii, Yoichi| Sugawara, Eiji| Hayashi, Kazuhiko| Sano, Shunji|
Abstract <p>Intrathymic (i.t.) injection of allogenic cells without administration of anti-lymphocyte serum (ALS) in neonatal recipients has induced donor-specific tolerance to subsequent cardiac allografts in rats. This study examines whether similar tactics can be successfully applied to a hamster-to-rat cardiac xenotransplantation model. Lewis neonates on their first day of life underwent i.t., subcutaneous (s.c.), intraperitoneal (i.p.), or intravenous (i.v.) injections of 5 x 10(7) Golden Syrian hamster splenocytes. After six weeks, the rats underwent heterotopic cardiac transplantation of hamster hearts. Cyclophosphamide (CyP) was administered on the day before surgery and postoperatively to suppress antibody-mediated graft rejection. Rats given splenocytes with 80 mg/kg of CyP had the following graft survival times: 8 to 12 days for i.t. injection (mean, 9.4 days); 5 to 7 days for s.c. injection (mean, 6.6 days); 4 to 11 days for i.p. injection (mean, 7.4 days); and 4 to 13 days for i.v. injection (mean, 7.9 days). Only the extension of graft survival produced by i.t. injection was statistically significant in comparison with the rats given only CyP treatment (mean, 7.5 days; P &#60; 0.05). Thus, it appears that i.t. injection of xenogenic splenocytes in neonatal recipients with administration of CyP, but without ALS, can prolong xenograft survival. This biological intervention may be most useful in pediatric xenotransplantation when combined with other immunomodulation techniques.</p>
Keywords intrathymic injection neonatal tolerance xenografts
Amo Type Article
Published Date 1998-04
Publication Title Acta Medica Okayama
Volume volume52
Issue issue2
Publisher Okayama University Medical School
Start Page 83
End Page 88
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 9588223
Web of Sience KeyUT 000073363000003
JaLCDOI 10.18926/AMO/30884
FullText URL fulltext.pdf
Author Sano, Shunji| Yokota, Yoshio| Makino, Seiichiro|
Abstract <p>Seventeen patients having extracardiac valved conduits placed between the right ventricle and pulmonary artery were followed for 7 to 87 months postoperatively (mean, 42 months), at the Heart Institute, Kenritsu Amagasaki Hospital, Japan. There were no late deaths in the study group. Three conduits have been replaced, all because of conduit stenosis. In two-dimensional echocardiographic examinations, commissural fusion and calcification of the valve were noted in 6 out of 16 xenograft valved conduits. Mechanical valve immobility was found in one patient. Neointimal peel of the dacron graft was noted in 6 out of 17 cases, and marked left ventricular deformity in the short axis view was found in 6. Late cardiac catheterization was done in 6 patients who were suspected of having valve failure and right ventricular hypertension by two-dimensional echocardiography. All 6 of these patients showed a high pressure gradient between the pulmonary artery and right ventricle and also had elevated right ventricular pressure. In conclusion, two-dimensional echocardiography is a simple, non-invasive and very accurate method for detecting conduit stenosis and valve failure. An echocardiographic series should be performed for a long-time postoperatively because obstructions of valved conduits may be progressive, and an operation may be advisable in order to prevent the development of advanced right ventricular hypertrophy and deterioration.</p>
Keywords extracardiac valved conduit conduit stenosis two-demensional echocardiography
Amo Type Article
Published Date 1989-06
Publication Title Acta Medica Okayama
Volume volume43
Issue issue3
Publisher Okayama University Medical School
Start Page 175
End Page 184
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 2763867
Web of Sience KeyUT A1989AG01600006
JaLCDOI 10.18926/AMO/30856
FullText URL fulltext.pdf
Author Sano, shunji| Nawa, Sugato| Senoo, Yoshimasa| Teramoto, Shigeru|
Abstract <p>Dynamic ergometer exercise in a supine position was applied to 64 patients more than 1 year after valvular heart surgery, and the left ventricular reserve was evaluated echocardiographically. The left ventricular reserve declined in the mitral stenosis-mitral valve replacement group, while it was better maintained in the mitral stenosis-mitral commissurotomy, aortic regurgitation and aortic stenosis groups. The patients were divided into 3 groups depending on whether the percentage increase during exercise of stroke index, an index of left ventricular pump function, increased, unchanged, or decreased. The percentage increase of mean velocity of circumferential fibre shortening (y) and that of left ventricular end-diastolic diameter (x) during exercise were plotted for each group. The increased group was isolated from the unchanged group by the line of y = -5.02x + 30.1; the unchanged group was isolated from the decreased group by that of y = -5.68x-10.0, and the increased and unchanged groups were clearly isolated from the decreased group by that of y = -6.86x-4.76. We conclude that dynamic ergometer exercise echocardiography is useful for evaluating the left ventricular reserve of postoperative patients with valvular heart disease. It was also thought that the subclinical state of cardiac failure can be effectively detected by the present method.&#60;/P&#62;</p>
Keywords left ventricular reserve dynamic exercise echocardiography valvular heart disease ergometer
Amo Type Article
Published Date 1989-08
Publication Title Acta Medica Okayama
Volume volume43
Issue issue4
Publisher Okayama University Medical School
Start Page 223
End Page 231
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 2801186
Web of Sience KeyUT A1989AP79100004