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ID 13178
Eprint ID
13178
FullText URL
Thumnail 119_57.pdf 282 KB
Title Alternative
Effects of oral morphine for pain relief of peripheral arterial disease
Author
Matsusaki, Takashi
Miyake, Asako
Kaku, Ryuji
Matsumi, Masaki
Kiyoshi, Morita
Abstract
Peripheral arterial disease often causes ischemic ulcers due to impaired blood flow and consequentially induces intractable pain. For these patients, we have recently begun to administer morphine orally. In this study, we retrospectively examined the effects of oral morphine for the relief of pain caused by peripheral arterial disease. Oral morphine was administered to 17 cases of peripheral arterial disease between January, 2004 and February, 2006. The initial dosage was 5 mg or 10 mg, started on an as-needed basis. After the daily dosage of morphine became constant, we divided the dosage into four or six times a day and administered it regularly. With the exception of one case, a small amount of oral morphine, from 20 mg to 70 mg a day, could alleviate patient's pain. Eight cases had side effects such as nausea, constipation or drowsiness. Oral morphine is effective for pain relief of peripheral arterial disease patients. However, now in Japan, oral morphine, which we can prescribe for those patients with insurance, has a shorter duration of action, so we need to administer slow-release morphine. Oral morphine must be administered carefully because many peripheral arterial disease patients have cardiac disease or renal dysfunction as complications.
Keywords
末梢血行障害 (peripheral arterial disease)
モルヒネ (oral morphine)
疼痛管理 (pain management)
虚血性潰瘍 (ischemic ulcer)
Note
原著
Published Date
2007-05-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume119
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
57
End Page
60
ISSN
00301558
NCID
AN00032489
Content Type
Journal Article
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma