Author Takabatake, Shota| Fukumoto, Yusei| Ohtsuka, Satomi| Kanayama, Naoki| Magari, Masaki| Sakagami, Hiroyuki| Hatano, Naoya| Tokumitsu, Hiroshi|
Keywords CaMKKβ Phosphorylation Dephosphorylation PP1 PP2A Okadaic acid
Note This fulltext is available in Feb. 2021.|
Published Date 2020-04-23
Publication Title Biochemical and Biophysical Research Communications
Volume volume525
Issue issue1
Publisher Academic Press
Start Page 251
End Page 257
ISSN 0006-291X
NCID AA00564395
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 32085894
DOI 10.1016/j.bbrc.2020.02.056
Web of Science KeyUT 000526797700039
Related Url isVersionOf https://doi.org/10.1016/j.bbrc.2020.02.056
FullText URL BBA_1863_4_672.pdf
Author Takabatake, Shota| Ohtsuka, Satomi| Sugawara, Takeyuki| Hatano, Naoya| Kanayama, Naoki| Magari, Masaki| Sakagami, Hiroyuki| Tokumitsu, Hiroshi|
Keywords CaMKK Calmodulin Intracellular Ca(2+) PKA Phosphorylation Signal transduction
Published Date 2019-01-17
Publication Title Biochimica et Biophysica Acta (BBA) - General Subjects
Volume volume1863
Issue issue4
Publisher Elsevier Science
Start Page 672
End Page 680
ISSN 0304-4165
NCID AA00564679
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 30660766
DOI 10.1016/j.bbagen.2018.12.012
Web of Science KeyUT 000460853200003
Related Url isVersionOf https://doi.org/10.1016/j.bbagen.2018.12.012
FullText URL BBRC_485_2_261.pdf
Author Kawaguchi, Yuka| Nariki, Hiroaki| Kawamoto, Naoko| Kanehiro, Yuichi| Miyazaki, Satoshi| Suzuki, Mari| Magari, Masaki| Tokumitsu, Hiroshi| Kanayama, Naoki|
Keywords AID DT40 Gene conversion Ig SRSF1 Somatic hypermutation
Published Date 2017-04
Publication Title Biochemical and Biophysical Research Communications
Volume volume485
Issue issue2
Publisher Elsevier
Start Page 261
End Page 266
ISSN 0006-291X
NCID AA00564395
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 28235482
DOI 10.1016/j.bbrc.2017.02.097
Web of Science KeyUT 000396798300007
Related Url isVersionOf https://doi.org/10.1016/j.bbrc.2017.02.097
JaLCDOI 10.18926/46955
FullText URL mfe_38_1-2_091_096.pdf
Author Kanayama, Naoki| Yamakoshi, Kimi| Kiyomi, Masaaki| Magari, Masaki| Ohmori, Hitoshi|
Abstract Generally, IgM antibodies (Abs) produced in a primary immune response show lower affinity for an inducing antigen (Ag) compared with the corresponding IgG Abs that are major switched isotypes formed in the secondary response. An IgM molecule is a pentamer with 10 Ag-binding sites that will contribute to an increase of avidity for an Ag. To estimate the contribution of the pentameric structure to the avidity of an IgM Ab, we generated IgM and IgG1 monoclonal Abs (mAbs) with identical V regions that are specific for 4-hydroxy-3-nitrophenylacetyl (NP) by in vitro class switching of B cells followed by the cell fusion with a mouse myeloma cell line. Compared with an anti-NP IgG1 mAb, the corresponding IgM mAb showed much higher avidity for NP-conjugated bovine serum albumin, which was drastically reduced after being dissociated into monomers.
Publication Title Memoirs of the Faculty of Engineering, Okayama University
Published Date 2004-03
Volume volume38
Issue issue1-2
Start Page 91
End Page 96
ISSN 0475-0071
language 英語
File Version publisher
NAID 80017001822