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ID 53340
JaLCDOI
FullText URL
69_2_113.pdf 1.14 MB
Author
Inada, Ryo
Toshima, Toshiaki
Mori, Yoshiko
Kondo, Yoshitaka ORCID Kaken ID researchmap
Kishimoto, Hiroyuki Kaken ID
Oshiro, Taihei
Kanemitsu, Yukihide
Abstract
A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control.
Keywords
colorectal cancer
recurrence
total pelvic exenteration
radiofrequency ablation
systemic chemotherapy
Amo Type
Case Report
Published Date
2015-04
Publication Title
Acta Medica Okayama
Volume
volume69
Issue
issue2
Publisher
Okayama University Medical School
Start Page
113
End Page
118
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2015 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT