| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Norio| Sukegawa, Shintaro | Kitamura, Akira| Goto, Ryosuke| Noda, Tomoyuki| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Kawasaki, Keisuke| Furuki, Yoshihiko| Ozaki, Toshifumi| |
| Keywords | osteoporosis deep learning hip radiograph ensemble model |
| Published Date | 2020-11-10 |
| Publication Title | Biomolecules |
| Volume | volume10 |
| Issue | issue11 |
| Publisher | MDPI |
| Start Page | 1534 |
| ISSN | 2218-273X |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 33182778 |
| DOI | 10.3390/biom10111534 |
| Web of Science KeyUT | 000592980100001 |
| Related Url | isVersionOf https://doi.org/10.3390/biom10111534 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakata, Eiji| Sugihara, Shinsuke| Sugawara, Yoshifumi| Nakahara, Ryuichi| Furumatsu, Takayuki| Tetsunaga, Tomonori| Kunisada, Toshiyuki| Nakanishi, Kazuo| Ozaki, Toshifumi| |
| Keywords | bone metastasis multidisciplinary treatment skeletal-related event malignant spinal cord compression neurological deficit |
| Published Date | 2020-02-20 |
| Publication Title | Oncology Letters |
| Volume | volume19 |
| Issue | issue4 |
| Publisher | Spandidos Publications |
| Start Page | 3137 |
| End Page | 3144 |
| ISSN | 1792-1074 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Nakata et al. |
| File Version | publisher |
| PubMed ID | 32218864 |
| DOI | 10.3892/ol.2020.11415 |
| Web of Science KeyUT | 000523763900064 |
| Related Url | isVersionOf https://doi.org/10.3892/ol.2020.11415 |
| JaLCDOI | 10.18926/AMO/49259 |
|---|---|
| FullText URL | 67_1_65.pdf |
| Author | Sakata, Kenichiro| Furumatsu, Takayuki| Abe, Nobuhiro| Miyazawa, Shinichi| Sakoma, Yoshimasa| Ozaki, Toshifumi| |
| Abstract | Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in human osteoarthritis. We retrospectively investigated cartilage repairs after marrow stimulation for the treatment of large cartilage defects in osteoarthritic knees. Tissues were obtained from patients who underwent total knee arthroplasty (TKA) after arthroscopic marrow stimulation in medial compartmental osteoarthritis. Clinical findings and cartilage repair were assessed. Sections of medial femoral condyles were histologically investigated by safranin O staining and anti-type II collagen antibody. Marrow stimulation decreased the knee pain in the short term. However, varus leg alignment gradually progressed, and TKA conversions were required. The grade of cartilage repair was not improved. Marrow stimulations resulted in insufficient cartilage regeneration on medial femoral condyles. Safranin O-stained proteoglycans and type II collagen were observed in the deep zone of marrow-stimulated holes. This study demonstrated that marrow stimulation resulted in failed cartilage repair for the treatment of large cartilage defects in osteoarthritic knees. Our results suggest that arthroscopic marrow stimulation might not improve clinical symptoms for the long term in patients suffering large osteoarthritic cartilage defects. |
| Keywords | bone marrow stimulation microfracture subchondral drilling osteoarthritis of the knee cartilage repair |
| Amo Type | Case Report |
| Published Date | 2013-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 65 |
| End Page | 74 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439511 |
| Web of Science KeyUT | 000316829900009 |
| FullText URL | OTSR105_1_107.pdf Fig.pdf |
|---|---|
| Author | Furumatsu, Takayuki| Okazaki, Yuki| Okazaki, Yoshiki| Hino, Tomohito| Kamatsuki, Yusuke| Masuda, Shin| Miyazawa, Shinichi| Nakata, Eiji| Hasei, Joe| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Keywords | Descending knee motion Injury pattern Medial meniscus Posterior root tear Squatting |
| Published Date | 2019-02-28 |
| Publication Title | Orthopaedics & Traumatology: Surgery & Research |
| Volume | volume105 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 107 |
| End Page | 111 |
| ISSN | 18770568 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30442555 |
| DOI | 10.1016/j.otsr.2018.10.001 |
| Web of Science KeyUT | 000456541300018 |
| Related Url | isVersionOf https://doi.org/10.1016/j.otsr.2018.10.001 |
| FullText URL | IntOrthop_43_5_1239.pdf Tables.pdf Fig.pdf |
|---|---|
| Author | Furumatsu, Takayuki| Miyazawa, Shinichi| Fujii, Masataka| Tanaka, Takaaki| Kodama, Yuya| Ozaki, Toshifumi| |
| Keywords | Arthroscopic scoring Medial meniscus Meniscal healing Posterior root tear Transtibial pullout repair |
| Published Date | 2018-08-01 |
| Publication Title | International Orthopaedics |
| Volume | volume43 |
| Issue | issue5 |
| Publisher | Springer |
| Start Page | 1239 |
| End Page | 1245 |
| ISSN | 03412695 |
| NCID | AA0068148X |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30069591 |
| DOI | 10.1007/s00264-018-4071-z |
| Web of Science KeyUT | 000466730800024 |
| Related Url | isVersionOf https://doi.org/10.1007/s00264-018-4071-z |
| JaLCDOI | 10.18926/AMO/53910 |
|---|---|
| FullText URL | 69_6_355.pdf |
| Author | Okada, Yukimasa| Furumatsu, Takayuki| Miyazawa, Shinichi| Tanaka, Takaaki| Fujii, Masataka| Ozaki, Toshifumi| Abe, Nobuhiro| |
| Abstract | Venous thromboembolism (VTE) is a potential complication occurring after total knee arthroplasty (TKA). We investigated the incidence of VTE after TKA using contrast-enhanced computed tomography (CT), and assessed the efficacy of VTE prophylaxis (fondaparinux and enoxaparin). At our hospital, 189 patients (225 knees) underwent TKA between April 2007 and October 2011. The 225 knees were divided into a control group with no VTE prophylaxis (31 cases), a fondaparinux group (107 cases), and an enoxaparin group (87 cases). Contrast-enhanced CT screening for VTE was performed in all cases on day 5 or 6 after TKA. D-dimer levels were measured on day 5 after TKA, and were significantly lower in the fondaparinux (9.8±3.8) and enoxaparin groups (9.4±4.9) than in the control group (15.6±9.8) (p＜0.001). However, no statistically significant difference in the incidence of VTE was observed among the groups (control, 61.3%;fondaparinux, 49.5%;enoxaparin, 50.6%). Prophylaxis was not effective for the prevention of VTE as detected by contrast-enhanced CT after TKA. CT should be performed after TKA, even when VTE prophylaxis is used. |
| Keywords | venous thromboembolism contrast-enhanced computed tomography total knee arthroplasty fondaparinux enoxaparin |
| Amo Type | Original Article |
| Published Date | 2015-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume69 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 355 |
| End Page | 359 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26690246 |
| Web of Science KeyUT | 000368434500005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Joko, Ryoji| Yamada, Daisuke| Nakamura, Masahiro| Yoshida, Aki| Takihira, Shota| Takao, Tomoka| Lu, Ming| Sato, Kohei| Ito, Tatsuo| Kunisada, Toshiyuki| Nakata, Eiji| Ozaki, Toshifumi| Takarada, Takeshi| |
| Keywords | PRRX1 Osteosarcoma Tumor malignancy Invasion Drug resistance Connectivity map analysis |
| Published Date | 2021-01 |
| Publication Title | Translational Oncology |
| Volume | volume14 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 100960 |
| ISSN | 1936-5233 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| PubMed ID | 33395745 |
| DOI | 10.1016/j.tranon.2020.100960 |
| Web of Science KeyUT | 000604582300006 |
| Related Url | isVersionOf https://doi.org/10.1016/j.tranon.2020.100960 |
| Author | Kunisada, Toshiyuki| Ozaki, Toshifumi| |
|---|---|
| Published Date | 2008-05-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue1 |
| Content Type | Journal Article |
| FullText URL | CTR_2019_1631298.pdf Fig.pdf |
|---|---|
| Author | Hino, Tomohito| Furumatsu, Takayuki| Miyazawa, Shinichi| Fujii, Masataka| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Ozaki, Toshifumi| |
| Keywords | Medial meniscus posterior insertion histological analysis knee osteoarthritis medial meniscus posterior root tear transtibial pullout repair |
| Published Date | 2019-07-09 |
| Publication Title | Connective Tissue Research |
| Volume | volume61 |
| Issue | issue6 |
| Publisher | Taylor and Francis |
| Start Page | 546 |
| End Page | 553 |
| ISSN | 0300-8207 |
| NCID | AA00615033 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31181971 |
| DOI | 10.1080/03008207.2019.1631298 |
| Web of Science KeyUT | 000478374800001 |
| Related Url | isVersionOf https://doi.org/10.1080/03008207.2019.1631298 |
| JaLCDOI | 10.18926/AMO/57717 |
|---|---|
| FullText URL | 73_6_523.pdf |
| Author | Hiranaka, Takaaki| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Masuda, Shin| Okazaki, Yuki| Takihira, Shota| Miyazawa, Shinichi| Nakata, Eiji| Ozaki, Toshifumi| |
| Abstract | The case of an individual with a bilateral anterior cruciate ligament (ACL) tear combined with a medial meniscus (MM) posterior root tear is described. A 34-year-old Japanese man with bilateral ACL rupture that occurred > 10 years earlier was diagnosed with bilateral ACL tear combined with MM posterior root tear (MMPRT). We performed a transtibial pullout repair of the MMPRT with ACL reconstruction. The tibial tunnels for the MM posterior root repair and ACL reconstruction were created separately. Postoperatively, a good clinical outcome and meniscal healing were obtained. Our surgical technique may thus contribute to anatomical MM posterior root repair and ACL reconstruction. |
| Keywords | bilateral anterior cruciate ligament tear medial meniscus posterior root tear pullout repair case report |
| Amo Type | Case Report |
| Published Date | 2019-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume73 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 523 |
| End Page | 528 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31871335 |
| Web of Science KeyUT | 000503431400008 |
| Author | 尾﨑 敏文| |
|---|---|
| Published Date | 2006-01-04 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume117 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/30739 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Aiga, Ayako| Asaumi, Koji| Lee, You Jin| Kadota, Hiroaki| Mitani, Shigeru| Ozaki, Toshifumi| Takigawa, Masaharu| |
| Abstract | The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation. After osteotomy, a 7-day lag phase was followed by distraction at the rate of 0.25 mm/12 h for 21 days (distraction phase), and a 7-day consolidation phase. The localization of neurotrophins (NGF, BDNF and NT-3) and their receptors tropomyosinrelated kinases (TRKA, TRKB and TRKC) by immunostaining showed positive staining in bone forming cells in each stage, although the presence and staining intensity varied by cell type and phase. The expressions of NGF, BDNF and NT-3 by real-time polymerase chain reaction (real-time PCR) showed that the peak of the mRNA expression of NGF occurred 10 days after distraction. NT-3 increased during bone extension, but decreased when distraction stopped. In contrast, BDNF continued to increase gradually throughout the distraction and consolidation phases. These findings suggest that neurotrophins and their receptors may play different roles in endochondral and intramembranous ossification in distraction osteogenesis. The tension stress caused by distraction may stimulate the expression of neurotrophins and their receptors, and promote osteogenesis. |
| Keywords | neurotrophin Trk distraction osteogenesis mechanical stress |
| Amo Type | Article |
| Published Date | 2006-10 |
| Publication Title | Acta Medica Okayama |
| Volume | volume60 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 267 |
| End Page | 277 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 17072373 |
| Web of Science KeyUT | 000241509000003 |
| JaLCDOI | 10.18926/AMO/30749 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Komiyama, Takamitsu| Nishida, Keiichiro| Yorimitsu, Masanori| Doi, Hideyuki| Miyazawa, Shinichi| Kitamura, Ai| Yoshida, Aki| Nasu, Yoshihisa| Abe, Nobuhiro| Ozaki, Toshifumi| |
| Abstract | Ossification disturbance in femoral head reportedly is seen in the Spontaneously Hypertensive rats (SHR) between ages of 10 and 20 weeks. We investigated serum and tissue levels of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) in SHR relevant to the ossification disturbance and osteonecrosis of the femoral head. Serum levels of IGF-1 and VEGF were significantly lower in SHR than in Wistar Kyoto rats (WKY) at weeks 5, 10, 15 and 20 (p<0.005). The incidence of histological ossification disturbance of the femoral head was higher in SHR (59%) than in WKY (40%) at week 20. Lower serum and local levels of VEGF in SHR appeared to be related to the incomplete ossification of the femoral heads. Immunohistochemical study showed significantly lower numbers of IGF-1 and VEGF positive chondrocytes in the femoral epiphyseal cartilage of SHR than in those of WKY at weeks 10, 15 and 20. Our results suggest that local and/or systemic levels of IGF-1 and VEGF between ages of 5 and 20 weeks might play roles in the pathogenesis of ossifi cation disturbance of the femoral head in SHR. |
| Keywords | spontaneous hypertensive rats insulin like growth factor-1 vascular endothelial growth factor ossification disturbance osteonecrosis |
| Amo Type | Article |
| Published Date | 2006-06 |
| Publication Title | Acta Medica Okayama |
| Volume | volume60 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 141 |
| End Page | 148 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 16838042 |
| Web of Science KeyUT | 000238503600001 |
| JaLCDOI | 10.18926/AMO/30776 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Makihata, Eiichi| Kuroda, Masahiro| Kawai, Akira| Ozaki, Toshifumi| Sugihara, Shinsuke| Inoue, Hajime| Joja, Ikuo| Asaumi, Junichi| Kawasaki, Shoji| Hiraki, Yoshio| |
| Abstract | <p>We report the results of phase I/II studies of preoperative multidisciplinary treatment of 14 patients with soft tissue sarcoma using hyperthermia from November 1990 to April 1995. The preoperative treatment was conducted with thermo-radio-chemotherapy in 11 cases of stage III, and with thermo-radiotherapy as well as thermo-chemotherapy in three cases of stages I and II. Hyperthermia was carried out twice a week with totals ranging from 4 to 14 times (average: 8.4 times); each session lasted 60min. Radiotherapy was administered four or five times per week, and the dose was 1.8 2Gy/fraction, with a total of 30-40Gy in a four week period. Chemotherapy was mainly in the form of MAID regimen (2-mercaptoethanesulphonic acid (mesna), adriamycin, ifosfamide and dacarbazine). The tumors were surgically resected in all patients after completing the preoperative treatment. The efficacy rate, as expressed by the percentage of either tumors in which reduction rate was 50% or more, or tumors for which post-treatment contrast enhanced CT image revealed low density volumes occupying 50% or more of the total mass, was 71 % (ten of the 14 tumors). The mean tumor necrosis rate in the resected specimens was 78%. The tumor necrosis rate was significantly high (P < 0.05) in patients whose Time ≥ 42°C was of long duration. Postoperative complications were observed in six patients; among these, two patients developed wound infection that required surgical treatment as a complication of surgery performed in the early stage following the preoperative treatment. After a mean postoperative follow-up of 27 months, distant metastasis occurred in four patients resulting in three fatalities. The three-year cumulative survival rate was 64.3%. No local recurrence was observed in any patient during the follow-up, thus confirming our hypothesis that preoperative multidisciplinary treatment has an excellent local efficacy. We think that it would be valuable to conduct, at many facilities, phase III studies on the treatment of soft tissue sarcoma by a combination of surgery and preoperative multidisciplinary treatment using hyperthermia, paying close attention to the interval between these two modalities.</p> |
| Keywords | soft tissue tumor hyperthermia radiotherapy chemotherapy |
| Amo Type | Article |
| Published Date | 1997-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume51 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 93 |
| End Page | 99 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 9142346 |
| Web of Science KeyUT | A1997WX19600006 |
| JaLCDOI | 10.18926/AMO/30784 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Kunisada, Toshiyuki| Kawai, Akira| Ozaki, Toshifumi| Sugihara, Shinsuke| Taguchi, Kohji| Inoue, Hajime| |
| Abstract | <p>In this study, we reviewed the clinical features of 11 patients with malignant schwannoma who were treated in our institute. Five patients had coexistent von Recklinghausen's disease and one of them showed multifocal occurrence. Patients with the centrally located tumors had a poorer prognosis than those with the others. The overall 3-year survival rate was 36%; 40% in patients with von Recklinghausen's disease and 33% in the others. At the time of the last follow-up, 9 patients had died of the tumor, one continued to be tumor free, and one was alive with tumor. Postoperative local recurrence developed in 5 patients (45%); 4 out of 6 patients (67%) who underwent a marginal excision and one out of 3 (33%) who underwent primary amputation. There was no local recurrence in patients after a wide excision with at least 3cm of normal tissue removed surrounding the tumor in all directions. Nine patients (82%) developed pulmonary metastasis. The effect of adjuvant chemotherapy was not clear in this study. The high risk of pulmonary metastasis in this disease indicates the necessity of more effective adjuvant chemotherapy.</p> |
| Keywords | malignant schwannoma clinical analysis von Recklinghausen's disease |
| Amo Type | Article |
| Published Date | 1997-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume51 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 87 |
| End Page | 92 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 9142345 |
| Web of Science KeyUT | A1997WX19600005 |
| JaLCDOI | 10.18926/AMO/30956 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Doi, Hideyuki| Nishida, Keiichiro| Yorimitsu, Masanori| Komiyama, Takamitsu| Kadota, Yasutaka| Tetsunaga, Tomonori| Yoshida, Aki| Kubota, Satoshi| Takigawa, Masaharu| Ozaki, Toshifumi| |
| Abstract | <p>Mechanical stress plays a key role in the pathogenesis of cartilage destruction seen in osteoarthritis (OA). We investigated the effect of cyclic tensile stress (CTS) on the anabolic and catabolic gene expression of rat cultured normal chondrocytes using the Flexercell strain unit. The effects of interleukin (IL)-4, a chondroprotective cytokine, on the changes in gene expression induced by CTS were also investigated. CTS (7% elongation at 0.5 Hz) for 24 h did not affect the expression of aggrecan and type II collagen, whereas CTS significantly upregulated matrix metalloproteinase (MMP)-13 and cathepsin B mRNA expression by chondrocytes. IL-1beta expression was also signifi cantly upregulated by CTS up to 12 h. The upregulation of MMP-13 was observed at 3 h, which was earlier than that of IL-1beta. Furthermore, pre-treatment with IL-4 (10 ng/ml) suppressed both MMP-13 and cathepsin B induction by mechanical stress, as well as CTS-induced IL-1beta expression. Our results suggest that IL-4 might have a therapeutic value in the treatment of OA by downregulation of mechanical stress-induced MMP-13 and cathepsin B expression by chondrocytes.</p> |
| Keywords | IL-4 MMP cathepsin B mechanical stress aggrecanase |
| Amo Type | Original Article |
| Published Date | 2008-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume62 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 119 |
| End Page | 126 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 18464888 |
| Web of Science KeyUT | 000255297600008 |
| JaLCDOI | 10.18926/AMO/31335 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Ozaki, Toshifumi| Nakatsuka, Yoichi| Kawai, Akira| Akazawa, Hirofumi| Kunisada, Toshiyuki| Inoue, Hajime| |
| Abstract | <p>There are few reports on skeletal reconstruction using the bone transport technique to repair bone defects caused by resections of tumors associated with osteosarcoma. We attempted to reconstruct a 23 cm bone defect after resection of an osteosarcoma of the left femur, and succeeded in gaining 17 cm by bone transport. Five years after surgery, this patient remains alive without metastasis or local recurrence.</p> |
| Keywords | osteosarcoma bone transport reconstruction |
| Amo Type | Article |
| Published Date | 1998-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume52 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 67 |
| End Page | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 9548997 |
| Web of Science KeyUT | 000072264100010 |
| JaLCDOI | 10.18926/AMO/31340 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Ozaki, Toshifumi| Nakatsuka, Yoichi| Kawai, Akira| Akazawa, Hirofumi| Kunisada, Toshiyuki| Inoue, Hajime| |
| Abstract | <p>There are few reports on skeletal reconstruction using the bone transport technique to repair bone defects caused by resections of tumors associated with osteosarcoma. We attempted to reconstruct a 23 cm bone defect after resection of an osteosarcoma of the left femur, and succeeded in gaining 17 cm by bone transport. Five years after surgery, this patient remains alive without metastasis or local recurrence.</p> |
| Keywords | osteosarcoma bone transport reconstruction |
| Amo Type | Article |
| Published Date | 1998-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume52 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 67 |
| End Page | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 9548997 |
| Web of Science KeyUT | 000072264100010 |
| JaLCDOI | 10.18926/AMO/31575 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Ozaki, Toshifumi| Sugihara, Shinsuke| Inoue, Hajime| |
| Abstract | <p>We report second malignant neoplasms which developed between 7 and 19 years after treatment in 3 pediatric patients with osteosarcoma. Two patients had been treated with only surgery, and another patient had been treated with a combination of surgery with chemotherapy and radiation therapy for primary lesions. Pediatric patients with osteosarcoma, in particular, require careful long-term follow-up to monitor not only metastases but also development of second malignant neoplasms.</p> |
| Keywords | osteosarcoma second malignancy |
| Amo Type | Article |
| Published Date | 1993-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume47 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 133 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 8506750 |
| Web of Science KeyUT | A1993LA45200010 |
| JaLCDOI | 10.18926/AMO/31814 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Minagawa, Hiroshi| Aiga, Ayako| Endo, Hirosuke| Mitani, Shigeru| Tetsunaga, Tomonori| Ozaki, Toshifumi| |
| Abstract | <p>This retrospective study assessed the radiographic results of 16 patients with avascular necrosis following treatment for developmental dislocation of the hip (DDH) who were subsequently treated between 1991 and 2005 by rotation acetabular osteotomy (RAO) combined with femoral intertrochan-teric osteotomy (FIO). Initial treatment was by Pavlik harness, cast fixation, or overhead traction. The parameters that showed consistent improvement were the index of centralization, the index of acetabular coverage, adequate reduction of the greater trochanter, and abductor sufficiency. The combined procedure appears to be effective in cases in which preoperative planning shows a reasonable expectation of congruency and osteoarthritis is limited to the early stages.</p> |
| Keywords | rotation acetabular osteotomy femoral intertrochanteric osteotomy combined procedure developmental dysplasia of hip avascular necrosis |
| Amo Type | Original Article |
| Published Date | 2009-08 |
| Publication Title | Acta Medica Okayama |
| Volume | volume63 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 169 |
| End Page | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 19727201 |
| Web of Science KeyUT | 000269228400002 |
