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ID 53557
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Author
Yumoto, Tetsuya ORCID Kaken ID
Sato, Keiji
Ugawa, Toyomu researchmap
Ichiba, Shingo
Ujike, Yoshihito
Abstract
Hyponatremia, a common electrolyte disorder associated with traumatic brain injuries (TBIs), has high mortality and morbidity rates. The aim of this study was to identify the risk factors for hyponatremia associated with TBI. We retrospectively analyzed the cases of TBI patients who were admitted to the emergency intensive care unit at Okayama University Hospital between October 2011 and September 2014. A total of 82 TBI patients were enrolled. The incidences of hyponatremia (serum sodium level of<135mEq/L) and severe hyponatremia (serum sodium level of<130mEq/L) within the first 14 days after admission were 51オ (n=42) and 20オ (n=16), respectively. After admission, hyponatremia took a median period of 7 days to develop and lasted for a median of 3 days. Multivariate analysis demonstrated that higher fluid intake from days 1 to 3 and the presence of cranial fractures were risk factors for hyponatremia. The 58 patients with hyponatremia experienced fewer ventilator-free days, longer intensive care unit stays, and less favorable outcomes compared to the 24 patients without hyponatremia;however, these differences were not significant. Further studies are needed to determine the optimal management strategy for TBI-associated hyponatremia in the intensive care unit setting.
Keywords
traumatic brain injury
hyponatremia
cranial fracture
fluid intake
Amo Type
Original Article
Published Date
2015-08
Publication Title
Acta Medica Okayama
Volume
volume69
Issue
issue4
Publisher
Okayama University Medical School
Start Page
213
End Page
218
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2015 by Okayama University Medical School
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publisher
Refereed
True
PubMed ID
Web of Science KeyUT