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ID 48974
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Author
Hyakutake, Toru
Hashimoto, Yuki
Yanase, Shinichiro Kaken ID publons researchmap
Abstract
This paper describes a study in which numerical simulations were applied to improve the separation efficiency of a microfluidic-based sperm sorter. Initially, the motion of 31 sperm were modeled as a sinusoidal wave. The modeled sperm were expected to move while vibrating in the fluid within the microchannel. In this analysis, the number of sperm extracted at the outlet channel and the rate of movement of the highly motile sperm were obtained for a wide range of flow velocities within the microchannel. By varying the channel height, and the width and the position of the sperm-inlet channel, we confirmed that the separation efficiency was highly dependent on the fluid velocity within the channel. These results will be valuable for improving the device configuration, and might help to realize further improvements in efficiency in the future.
Keywords
Human reproduction
Microfluid
Numerical simulation
Separation efficiency
Sperm sorter
Published Date
2009-02
Publication Title
Biomedical Microdevices
Volume
volume11
Issue
issue1
Publisher
Springer US
Start Page
25
End Page
33
ISSN
1387-2176
Content Type
Journal Article
Project
Research Core for Interdisciplinary Sciences
Official Url
http://link.springer.com/article/10.1007%2Fs10544-008-9207-2
language
英語
Copyright Holders
© Springer Science+Business Media, LLC 2008
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Refereed
True
DOI
PubMed ID
Web of Science KeyUT