Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Others
Author 三朝分院看護部|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1991-08
Publication Title 環境病態研報告
Volume volume62
Content Type Others
Author Yasuda, Tatsuji|
Published Date 1991-08
Publication Title 環境病態研報告
Volume volume62
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1991-08
Publication Title 環境病態研報告
Volume volume62
Content Type Others
Author Institute for Environmental Medicine, Okayama University Medical Scool|
Published Date 1991-08
Publication Title 環境病態研報告
Volume volume62
Content Type Others
Author 岡山大学医学部附属環境病態研究施設/岡山大学医学部附属病院三朝分院|
Published Date 1986-07
Publication Title 環境病態研報告
Volume volume57
Content Type Others
JaLCDOI 10.18926/19842
Title Alternative ステロイド依存性重症難治性喘息に対する温泉療法の遠隔効果
FullText URL 061_001_006.pdf
Author Tanazaki, Yoshiro| Sudo, Michiyasu| Kitani, Hikaru| Kawauchi, Kazuhisa| Mifune, Takashi| Okuda, Hiroyuki| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Abstract The immediate effects (IEs) and distant effects (DEs) of spa therapy were observed in 67 patients with steroid- dependent intractable asthma (SDIA). (1) The IEs of spa therapy evaluated one week after spa therapy were considerably high, and the efficacy rate was 61.5% in type Ⅰa, 82.7% in type Ⅰb, and 83.4% in type Ⅱ asthmatics. (2) The DEs of spa therapy on SDIA were also observed. The efficacy rate was 50.2% in type Ⅰa, 54.3% in type Ⅰb and 63.7% in type Ⅱ asthmatics. (3) The DEs of spa therapy were different between cases with and without maintenance therapy (MT). The efficacy rate of DEs was generally high (72.8~91.7%) in cases with MT, and low (16.7~40.0%) in cases without MT. These results show that MT is very important to keep the IEs of spa therapy high for a long time.
Abstract Alternative 67例のステロイド依存性重症難治性喘息を対象に,温泉療法を行い,その即時的効果(1週間後)および遠隔効果(1年後),さらには,温泉療法後の継続療法の影響などについて検討を加えた。1.温泉療法1週間後の即時的効果は比較的高く,その有効率は,Ⅰa.気管支攣縮型で61.5%,Ⅰb.気管支攣縮+過分泌型で82.7%,Ⅱ.細気管支閉塞型で83.4%であった。2.温泉療法の遠隔効果では,その有効率は,Ⅰa型で50.2%,Ⅰb型で54.1%,Ⅱ型で63.7%であった。3.温泉療法の遠隔効果は,その後の継続療法の有無によりかなり異なった結果であった。すなわち,継続療法を行った症例の有効率は,72.8~91.7%と高く,一方,継続療法を行わなかった症例の有効率は,16.7~40.0%の間にあった。これらの結果から,温泉療法の即時的効果を保つためには,その後の継続療法が極めて重要であることが示唆された。
Keywords lmmediate effects (即時的効果) Distant effects (遠隔効果) Maintenance therapy (継続療法) Spa therapy (温泉療法) Steroid-dependent intractable asthma (ステロイド依存性重症難治性喘息)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 1
End Page 6
ISSN 09133771
language 英語
File Version publisher
NAID 120002309169
Author Matsubara, Fumie| Endo, Hiroi| Sudo, Michiyasu| Tanizaki, Yoshiro|
Published Date 1989-07
Publication Title 環境病態研報告
Volume volume60
Content Type Data or Dataset
JaLCDOI 10.18926/19834
Title Alternative Application of personal computer system in nursing division. -(1) Programming for a roster-
Author Nakai, Mutsuo| Yoshida, Junko| Inagaki, Kikuko|
Publication Title 環境病態研報告
Published Date 1989-07
Volume volume60
Start Page 103
End Page 107
ISSN 09133771
language 日本語
File Version publisher
JaLCDOI 10.18926/19832
Title Alternative Analytic study on colon examination for the past three years.
FullText URL 060_100_102.pdf
Author Akiyama, Tsuneo| Nakai, Mutsuo| Ochi, Koji|
Publication Title 環境病態研報告
Published Date 1989-07
Volume volume60
Start Page 100
End Page 102
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002309110
JaLCDOI 10.18926/19828
Title Alternative A case report of linitis plastica type of colon cancer.
FullText URL 060_094_099.pdf
Author Hirai, Shunichi| Suzuka, Ichio| Morisue, Shinhachi| Soda, Mitsuhiro| Tokuno, Teruo| Komoto, Yoshiaki| Sunakawa, Mitsuru| Yorozu, Hidenori| 大塚 昭雄|
Abstract 原発性びまん浸潤型大腸癌は,全大腸癌症例の1%未満と比較的稀な疾患であり,一般大腸癌症例とくらべてその予後の悪いことで知られている。その原因の一つとして,確定診断の困難さがあるが,これは粘膜病変の欠如のために生検で確論がつきにくい点にある。我々の症例は,43歳の女性で,横行結腸に原発した症例である。腹痛を訴えて入院後,急速にイレウス状態となり,注腸検査で横行結腸の高度な狭窄を認めた。大腸ファイバースコープは腹痛のため病変部まで届かず,膣擦過細胞診およびダグラス窩穿刺腹水細胞診にて腺癌細胞を確認できた。手術所見はP(3)H(0)S(3)N(4)で,姑息切除に終わった。本症は手術時の進行度がきわめて高度であるので,本症を疑って確診のつかない症例には,上記のような細胞診も試みてみるべきと思われる。
Abstract Alternative A 43-year-old women, complaining of abdominal pain and menstrual irregularity was found suffering from adenocarcinoma of the transverse colon by cytology tests for vaginal smear and ascites. She was operated for colonic obstruction palliatively because of the extensive lesions and died 2 months after surgery for all that of the intensive cancer therapy. The histological diagnosis was primary linitis plastica type of carcinoma of the transverse colon. Carcer involvement to the ovaries and uterine tubes could possibly be responsible for the positive cytology test for vaginal smear. This rare type of careinoma demonstrates certain clinicopathological characteristics that differ from those of the ordinary colonic carcinomas, such as unfavourable prognosis with the difficulty for diagnosis due to minimal mucosal changes and the marked thickend wall of the tumor being unable to perform endoscopic studies.
Keywords びまん浸潤型大腸癌 スキルス大腸癌 (Scirrhous Carcinoma of the Colon) Ⅳ型大腸癌 Linitis Plastica型大腸癌 (Linitis Plastica Type of Carcinoma)
Publication Title 環境病態研報告
Published Date 1989-07
Volume volume60
Start Page 94
End Page 99
ISSN 09133771
language 日本語
File Version publisher
NAID 120002309174
JaLCDOI 10.18926/19825
Title Alternative Classification and concepts of pancreatitis
FullText URL 060_083_093.pdf
Author Harada, Hideo| Tanaka, Juntaro| Ochi, Koji| Matsumoto, Shuji| Ishibashi, Tadaaki| Seno, Toshinobu| Miyake, Hirofumi|
Abstract 膵炎の分類は膵臓研究の進歩とともに変遷を重ねたが,ここ20年間はマルセイユ分類(1963年)が国際的に広く用いられてきた。しかし最近,膵検査法の進歩と膵研究の知見の蓄積を背景にして,ケンブリッジ(1983年),マルセイユ(1984年),およびローマ(1988年)において分類の改訂を目的に国際シンポジウムが開催され,それぞれに新しい膵炎の分類が提案された。各分類には多くの共通点が見られるが重要な相違点もある。各分類を十分に理解していないとしばらくは混乱に陥ることが危惧される。幸い筆者の1人はこれらのシンポジウムに招待され参加する機会を得たので,成文の背景にある討議を詳しく紹介し,各分類を比較しながらその特徴を述べた。それとともに将来理想的な分類を完成するために今後検討すべき課題をも指摘した。そして,これら分類の当面の利用法に関する筆者らの提案を述べた。
Abstract Alternative The present paper is a review of the historical changes in the classification and concept of pancreatitis. The Marseille classification and concept had enjoyed its international popularity for more than 20 years since it was adopted at the first Marseille symposium in 1962. However, the recent advancement in the study of the pancreas led to the attempts to revise the classification and concept of pancreatitis : International Symposium in Cambridge in 1983, Second International Symposium in Marseille in 1984 and Symposium at the International Congress of Gastroenterology in Rome in 1988. As one of us was invited to the last two symposia, we described the details of the revised classification and concept of Marseille (1984) and of Marseille-Rome (1988) ; then, we described the similarities and differences between the Cambridge classification, the revised Marseille classification and the Marseille-Rome classification. Finally we summarized the subjects to be further investigated to make better classification of pancreatitis in the future.
Keywords 膵炎 分類 (Classification and concepts of pancreatitis) 急性膵炎 (Acute pancreatitis) 慢性膵炎 (Chronic pancreatitis)
Publication Title 環境病態研報告
Published Date 1989-07
Volume volume60
Start Page 83
End Page 93
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002309066
JaLCDOI 10.18926/19821
Title Alternative Interstitial matrix components in relation to the pathogenesis of fibrosis
FullText URL 060_076_082.pdf
Author Seno, Toshinobu| Harada, Hideo| Ochi, Koji| Tanaka, Juntaro| Matsumoto, Shuji| Ishibashi, Tadaaki| Takeda, Masahiko| Miyake, Hirofumi|
Abstract 慢性膵炎の症例は近年増加の一途をたどっており,その発症機序と病態の解明および対策の確立が急がれている。慢性膵炎の重要な所見の一つである膵間質線維化の発生機序の解明および早期発見法の確立は重要な課題であるが,従来の知見は断片的にすぎない。そこで,筆者らは膵線維化の系統的な研究を始めるにあたって,細胞間マトリックスの構成成分と線維化に関する従来の知見および今後の課題を整理した。細胞間マトリックスのうちでも特にコラーゲン,グリコサミノグリカン,フィブロネクチンをとりあげ,その構造と機能および組織の線維化形成における役割について文献的考察を行った。今後,膵組織および膵液中のプロリンハイドロキシラーゼ,コラーゲンとその型別分布および各型コラーゲンの比,ヘキソサミン,デルマタン硫酸,フィブロネクチン,ラミニンを検討することが重要と思われた。
Abstract Alternative Increasing numbers of patients with chronic pancreatitis have been reported all over the world, including Japan. Pathogenesis of chronic pancreatitis has remained to be revealed and the early detection has remaind difficult despite extensive investigations. Interstitial fibrosis forms one of the most important histopathological features of chronic pancreatitis along with loss of parenchyma and irregular dilatation of the ducts and ductules. However, only a limited numbers of reports have been pubiished on the pathogenetic mechanisms of interstitial fibrosis of the pancres, because tissue materials are not easily accessible and blood samples can hardly reflect the fibrotic process of the pancreas unlike the case of the iiver. Our Preliminary studies revealed that biochemical and immunochemical analysis of pure pancreatic juice, such as determination of collagen, hexosamine, fibronectin and proline hydroxylase, might reflect the fibrotic process of the pancreas. The results led us to review the earlier reports on inter-cellular matrix in relation to the formation of fibrosis to find suitable markers to be evaluated in the future systematic investigations. The review revealed that pure pancreatic juice should be analyzed for collagen, types of collagen, hexosamine, dermatan sulfate, fibronectin, larninin, proline hydroxylase, collagenase and cathepsin B(1).
Keywords 慢性膵炎 (Chronic pancreatitis) 膵の線維化 (Interstitial fibrosis of the pancreas) 膵間質成分 (Interstitial matrix of the pancreas)
Publication Title 環境病態研報告
Published Date 1989-07
Volume volume60
Start Page 76
End Page 82
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002309179