JaLCDOI 10.18926/792
Title Alternative In Vitro Rooting and Multiple Buds Formation from Asparagus Lateral Buds with Ancymidol
FullText URL 061_030_035.pdf
Author Mifune, Takashi| Kawauchi, Kazuhisa| Kitani, Hikaru| Sudo, Michiyasu| Tanizaki, Yoshiro|
Abstract 高齢者の増加やいわゆるcompromised hostの増加により,肺結核症の臨床像が変化してきている。肺結核に典型的な臨床像を呈さず,頻回の喀疾検査にても抗酸菌を証明できなかった6症例に対し,気管支肺胞洗浄(bronchoalveolar lavage:BAL)を施行し,得られた洗浄液・吸引液の塗抹標本から抗酸菌を証明し,気管支粘膜の変化を認めた。以上の結果より,気管支型の結核症が増加してきている可能性が考えられた。気管支肺胞洗浄は,気管支型の結核症を含め,結核症の診断に有効と考えられた。
Keywords 肺結核 (Pulmonary tuberculosis) 気管支型結核症 (Tuberculosis of mucous membrane) 気管支肺胞洗浄法 (Bronchoalveolar lavage) 抗酸菌 (Acid fast bacilli)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 30
End Page 35
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002304746
Author Matsubara, Fumie| Endou, Hiroi| Kitani, Hikaru| Tanizaki, Yoshiro|
Published Date 1991-08
Publication Title 環境病態研報告
Volume volume62
Content Type Data or Dataset
JaLCDOI 10.18926/11579
Title Alternative 気管支喘息患者末梢血好塩基球の抗ヒトIgEおよびカルシウムイオノフォァA23187に対する反応性について
FullText URL 061_016_022.pdf
Author Tanizaki, Yoshiro| Sudo, Michiyasu| Kitani, Hikaru| Kawauchi, Kazuhisa| Mifune, Takashi| Okuda, Hiroyuki| Komagoe, Haruki| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Abstract The release of histamine from basophils induced by anti-lgE and calcium ionophore A 23187 ( Cal) was examined in 27 patients with bronchial asthma and 7 healthy subjects, using a whole blood method. (1)The release of histamine induced by anti-IgE and CaI was significantly higher in atopic asthmatics than in non-atopic cases. (2) The histamine release with anti-lgE and CaI was significantly lower in cases with long-term steroid therapy compared to the release in cases without steroid therapy. (3) The release with anti-lgE and CaI was increased in cases with age of 0-39 years and in cases wpth age at onset of 0-39 years. (4) Anti-IgE induced release correlated to a certain extent with the release induced by CaI. These results show that basophil reactivity as expressed by histamine release changes under different conditions.
Abstract Alternative 気管支喘息27例および健康人7名を対象に,抗ヒトIgEおよびカルシウムイオノフォァA23187(CaI)刺激時の末梢血好塩基球からのヒスタミン遊離について検討を加えた。(1)抗ヒトIgEおよびCaI刺激時の好塩基球からのヒスタミン遊離は,非アトピー型喘息に比べ,アトピー型喘息において有意に高い値を示した。(2)これらの刺激物質によるヒスタミン遊離は,非使用例に比べ,ステロイド依存性喘息において低い傾向がみられた。また,年齢では39才以下,発症年齢では39才以下でヒズタミン遊離がより高い傾向がみられた。(3)血清IgE値の高い症例の好塩基球は,低い症例に比べより多くのヒスタミンを遊離する傾向がみられた。(4)全般的には,抗ヒトIgE刺激によるヒスタミン遊離とCaI刺激時の遊離との間にはある程度の相関がみられた。以上の結果より,好塩基球の反応性はいろいろの条件下でかなり異なることが示唆された。
Keywords Histamine release (ヒスタミン遊離) Basophils (好塩基球) Anti-lgE (抗ヒトIgE) Calcium ionophore A 23187 (カルシウムイオノフォァA23187) Bronchial asthma (気管支喘息)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 16
End Page 22
ISSN 0913-3771
language 英語
File Version publisher
NAID 120002313673
JaLCDOI 10.18926/11625
Title Alternative Spa therapy for chronic respiratory diseases - in subjects admitted in 1989. -
FullText URL 061_007_015.pdf
Author Tanizaki, Yoshiro| Sudo, Michiyasu| Kitani, Hikaru| Kawauchi, Kazuhisa| Mifune, Takashi| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Abstract 1989年1月より12月までの1年間に当院へ入院した慢性呼吸器疾患患者85例(延べ90例)を対象に,その背景因子,臨床的特徴,および温泉療法の臨床効果について検討を加えた。(1)対象85例のうちわけは,気管支喘息65例,肺気腫4例,肺結核症4例,アレルギー性肉芽腫性血管炎3例,閉塞性細気管支炎3例,気管支拡張症2例,慢性気管支炎2例,過敏性肺臓炎2例であり,昨年度と異なり肺結核がやや多かったことが特徴的であった。(2)これら85症例のうち,温泉療法を受けた症例は63例(74.1%)であった。(3)温泉療 法を受けた症例の地域分布では,鳥取県からの入院症例51例では32例(62.7%)であり,同様に岡山県からの入院症例20例では19例(95.0%),その他の県からの入院症例14例で12例(85.7%)であった。4.温泉療法の臨床効果は,気管支喘息では51例中著効14例,有効27例,やや有効8例,無効2例であり,明らかな有効例は41例(80.3%)であった。
Abstract Alternative Backgrounds and immunological characteristics were studied in patients with chronic respiratory diseases admitted at Misasa Branch Hospital in 1989. At the same time, clinical effects of spa therapy were evaluated for these patients. 1. Eighty five patients with chronic respratory diseases comprised 65 patients with bronchial asthma, 4 with pulmonary emphysema, 4 with lung tuberculosis, 3 with allergic granulomatous angitis, 3 with obstructive bronchiolitis, 2 with bronchiectasia, 2 with chronic bronchitis and 2 with hypersensitivity pneumonitis. 2. Sixty three patients (74.1%) out of the 85 cases had spa therapy. 3. Out of 51 patients coming from Tottori prefecture, 32 cases (62.7%) received spa therapy. On the other hand, spa therapy was carried out for 19 cases (95.0%) out of the 20 cases from Okayama prefecture, and for 12 cases (85.7%) out of the 14 cases from the other prefectures (long distant areas). 4. Many cases with bronchial asthma showed low serum levels of IgE (lower than 200 IU/ml), and frequency of positive skin reactions to various allergens was low in the patients with bronchial asthma. Serum cortisol levels were very low in patients with steroid-dependent asthma. 5. Spa therapy was effective in 41 cases (80.3%) out of the 51 patients with bronchial asthma. Spa therapy also effective for patients with obstructive bronchiolitis, and allergic granulomatous angitis.
Keywords 気管支喘息 (Bronchial asthma) 閉塞性細気管支炎 (Obstructive bronchiolitis) 慢性気管支炎 (Chronic bronchitis) 血清コーチゾール値 (Serum cortisol level) 温泉療法 (Spa therapy)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 7
End Page 15
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313875
JaLCDOI 10.18926/11643
Title Alternative Prevalence of urinary stress incontinence in women
FullText URL 062_023_026.pdf
Author Okuda, Hiroshi| Takatori, Akimasa| Izushi, Michihiro| Yoshida, Junko| Yamagami, Keiko| Sakata, Junko| Tanizaki, Yoshiro|
Abstract 三朝分院外来を訪れた女性患者を対象に尿失禁に関する18項目のアンケート調査を行った。その結果,全体の過半数が尿失禁の経験者であった。腹圧性尿失禁が大部分を占め,高齢になるほど 経産回数が多いほど頻度が高くなる傾向がみられた。そのうちの約1割に尿漏れの頻度と程度が重かった。以上より,尿失禁について積極的な啓蒙,診断,治療の必要性が認められた。
Abstract Alternative The prevalence of urinary stress incontinence was investigated in 93 women consulting in our hospital by means of a questionnaire survey. The survey showed that 52.7% of the total cases experienced the loss of urine. 87% of the cases with the loss of urine were the cases with stress incotinence. The prevalence of incontinence increased with age up to 69.2% in the 60's. A positive correlation was found between the number of childbirths and the prevalence of incontinence.
Keywords 腹圧性尿失禁 (Urinary stress incontinence)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 23
End Page 26
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313351
JaLCDOI 10.18926/11648
Title Alternative 種々の長さのスペーサーをもつハプテン化ボスファチジルエタノールアミンの新しい合成法
FullText URL 062_032_037.pdf
Author Ishimori, Yoshio| Yasuda, Tatuji|
Abstract The antigenicity of liposomes sensitized with haptenated phosphatidylethanolamine (PE) and the reactivity of the liposomes with complement depended on the length of the spacer between hapten and PE. To establish the optimal conditions for the assay, haptenated PE's with various length of spacers are required. In the previous method, hapten-spacer molecule was first synthesized to which PE was conjugated. Therefore, even different hapten molecules and different length of spacer molecules were used, every combination of hapten and spacer has to be synthesized. A new procedure for preparing hapten-spacer-PE was described here. We first prepared conjugates between PE and various length of spacer molecule, the terminal of which is an amino residue. These molecules react well with activated hapten molecules, giving a good yield of hapten-spacer-PE.
Abstract Alternative 人工脂質膜であるリボソームにハプテン化ホスファチジルエタノールアミン(PE)を挿入することで,リボソーム膜上での免疫反応の研究が進んでいる。いろいろな因子のなかでリボソーム表面とハプテン基の間のスペーサーの長さも重要な因子であることが判明してきた。このスペーサーの役割を研 究するためには汎用性のある合成法の開発が望まれている。これまでのハプテン基一スペーサー分子を結合する方法は種類の異なるハプテン基をもつ分子群を合成するには煩雑である。そこで種々のスペーサーをもつPEを先に合成することで種類の違うハプテン基をもち,異なるスペーサーをもつハプテン化脂質抗原の合成法を開発した。
Keywords Haptenated phosphatidylethanolamine (ハプテン化ホスファチジルエタノールアミン) Spacer (スペーサー) Liposomes (リポソーム)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 32
End Page 37
ISSN 0913-3771
language 英語
File Version publisher
NAID 120002313629
JaLCDOI 10.18926/11650
Title Alternative Maternity swimming at M isasa Hospital of Okayama University Medical School-Fourth report. The growth and development of babies who were born from the mothers who experienced the maternity swimming
FullText URL 062_027_031.pdf
Author Okuda, Hiroshi| Takatori, Akimasa| Kondo, Yuji| Sakata, Junko| Kamimoto, Manabu| Fujii, Junko| Masui, Etsuko| Nagae, Chiho| Kawahara, Mitsuko| Tanizaki, Yoshiro|
Abstract 第1報において妊婦水泳に関する妊婦の認識について報告し,第2報において妊婦水泳の現状とその適応について報告し,第3報にて妊婦水泳が循環器系に与える影響について報告した。今回は,母親が妊婦水泳を行い出生後1年以上経過した児の発育,発達状況についてアンケート調査を行った。その結果,発育e発達状況は艮好であった。現時点で全例正常な発達をしていた。このことより我々の行っている妊婦水泳は児の発育,発達に悪影響を及ぼさないことが確かめられた。
Abstract Alternative Seventy babies were born from the mothers who experienced maternity swimming in our hospital. The growth and development of 31 babies that were over 1 years old were investigated by means of a questionnaire survey. 62.5% of the total were answered. This survey showed that no babies had problems with their growth and development. These results suggest that maternal Swimmingmight have no hazardous effects on the fetus.
Keywords 妊婦水泳 (Maternity swimming) 児の発育・発達 (Growth and Development of the child)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 27
End Page 31
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313455
JaLCDOI 10.18926/11662
Title Alternative Thermological study on the coldness women - Second report. The relationship between the change of atmospheric temperature and body surface temperature in women with complaints of coldness in limbs
FullText URL 062_016_022.pdf
Author Takatori, Akimasa| Okuda, Hiroshi| Sekiba, Kaoru| Tanizaki, Yoshiro|
Abstract 季節毎の婦人の冷え性患者における全身の皮膚表面温度分布について,サーモグラフィを用いて検討した。その結果以下のことが判明した。1)冷え性は外気温が1カ月の最高気温が20℃,最低気温が10℃,平均気温で15℃以下になると発症しやすくなる。2)外気温が前記の条件において,中間温環境下でサーモグラフィ上,軀幹部の最高温度と四肢部の最低温度の差が8℃以上ある症例では99%の確率で冷えを訴えることが明かとなった。
Abstract Alternative From January to December in 1990, whole body temperature was measured in 79 women by using a thermotracer 6T66, and was compared to the change of atmospheric temperature.The difference between the highest temperature of the body and the lowest temperature of the limbs was more than 8℃ in women with complaints of coldness of limbs. This difference was observed in 88% of the women complaining coldness when the average atmospheric temperature in a month was more than 15℃.
Keywords 婦人の冷え性 (Coldness in women) サーモグラフィ (Thermography) 気温の変化 (Change of atmospheric temperature)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 16
End Page 22
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313602
JaLCDOI 10.18926/11664
Title Alternative A dietary survey in patients with chronic pancreatitis
FullText URL 062_011_015.pdf
Author Hayashimoto, Kanae| Ochi, Koji| Harada, Hideo| Tanaka, Juntaro| Takuma, Masae| Masui, Etsuko| Tanizaki, Yoshiro| Matsumoto, Shuji| Seno, Toshinobu| Izushi, Michihiro|
Abstract 食事療法は慢性膵炎治療の基本として重要であるが,その具体的な内容についてはあまり明確にされていない。今回,筆者らは慢性膵炎例の食事に関する全国調査の一部を担当したので,その成績を報告し,問題点と対策について考察した。対象は慢性膵炎間欠期の患者56名(男44名,女12名)である。(1)エネルギー摂取量では1日1,400kcal以下が16名(29%)にみられ,肥満度80~90%が7名および80%以下が9名という栄養状態と考え合わせて,食事の回数を増やしてでも摂取エネルギーの改善をはかる必要がある。(2)蛋白質および脂質摂取量についても同様な成績であり,消化酵素剤を投与しながら量的,質的な改善をはかる必要がある。(3)糖質については質的改善をはかる必要がある。(4)ビタミンとミネラルも不足傾向にあった。野菜の摂取不足が顕著であった。(5)診断確定後も禁酒できない患者が男17名(39%),女1名(8%)にみられ,その指導が重要な課題である。
Abstract Alternative Importance of diet therapy has been emphasized in chronic pancreatitis. However, concrete measures and programs of the diet therapy have remained to be studied. Therefore, Intractable Pancreatic Disease Study Group recently carried out a nation-wide questionnaire survey on the diets in patients with chronic pancreatitis under the auspIces of the Ministry of Health and Welfare. Attendant physicians were requested to report the nutritional states of their patients and the kinds and amounts of foods taken by their patients on three consecutive days. The nutritional state was evaluated by a body weight index calculated by the following formula:Body Weight Index (%) = Present Body Weight / Ideal Body Weight X 100. Daily nutritional intake (calorie, protein, fat, carbohydrate, and others) was calculated by dieticians according to the Food Exchange Table published by the Japanese Association of Diabetes. The present study constitutes a part of the group study. Patients consisted of 44 men and 12 women who fulfilled the diagnostic criteria proposed by the Japanese Society of Gastroenterology;20 men and 3 women had secondary diabetes mellitus. Following results and conclusions were obtained. (1) Average daily calorie intake of the patients was 1,759kcal as compared with 2,057kcal in the general population in Japan. Sixteen patients (28.6%) showed daily calorie intake less than 1,400 kcal and consequently poor nutritional states (6 patients with body weight indices less than 80% and 10 with 80-90%). It is important, therefore, to try to improve the daily calorie intake by increasing the frequency of diets in these patients. (2) Average daily intake of protein was 72.1 g (animal protein 38.1 g), only slightly less than 79.2 g (animal protein 41.7 g) in the general population. However, as many as 16 patients (28.6%) showed daily protein intake of less than 60 g and poor nutritional states as described above. It is important, therfore, to encourage patients to maintain the daily protein intake of more than 60 g by increasing the frequency of diets with oral administration of digestive enzymes. (3) Average daily intake of fat was 39.9 g (animal fat 23.8 g), approximately 20 g less than 58.3 g (animal fat 28.0 g) in the general population. As many as 17 patients (30.4%) showed daily fat intake of less than 30 g , and 16 of the 17 patients showed poor nutritional states as described above. It is important, therefore, to encourage patients to maintain the daily fat intake of more than 30 g (especially by increasing the amounts of vegetable oil) by increasing the frequency of diets with oral administration of digestive enzymes. (4) Average daily intake of carbohydrate was 278 g, almost equal to 289 g in the general population. However, many patients took as much as 48 g of carbohydrate in the from of cakes, plain sugar and alcohol beverages. Seventeen men (39%) and one woman (8%) had continued drinking alcohol beverages even after the diagnosis was made. It is important, therefore, to encourage patients to improve the quality of carbohydrate intake, although it is admittedly difficult to realize the ideal. (5) Intake of vitamins and minerals (especially calcium) also tended to be insufficient. Green vegetables were especially insufficient. (6) In conclusion, it is utmost important in chronic pancreatitis to perform periodical evaluation of nutritional intake and feed back the information to the treatment through a close patient-dietician-doctor relationship.
Keywords 慢性膵炎 (Chronic pancreatitis) 食事療法 (Diet therapy in chronic pancreatitis) 栄養状態 (Nutrition in chronic pancreatitis)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 11
End Page 15
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313896
JaLCDOI 10.18926/11666
Title Alternative Trial of a mass screening survery for detecting early pancreatic cancer
FullText URL 062_005_010.pdf
Author Matsumoto, Shuji| Ochi, Koji| Tanaka, Juntaro| Seno, Toshinobu| Harada, Hideo|
Abstract 早期膵癌を発見するためのスクリーニング法を確立するため,1986年6月1日から1990年6月30日までの期間のprospective studyを行った。対象は,人間ドックを目的として来院した患者を主とする三朝分院の外来患者1,748名である。一次スクリーニング検査として,血清アミラーゼ,エラスターゼI,腹部超音波検査(US)を施行し155名の要精検者が得られ,要精検率は8.9%であった。155名の要精検者に,二次検査として,USの再精査,ERCP,腹部CTを施行した。その結果,早期膵癌患者1名,進行膵癌患者4名を発見し,膵癌発見率は0.29%と良好な成績であった。加えて,一次スクリーニングの検査項目を限定することによりcost-benifitを改善することができた。発見された膵癌患者の3名は60歳代であった。また,年代別要精検率は加齢とともに上昇した。1年以後にfollow-up検査を受けた患者の数は641名でfoilow-up率は36.7%であり,そのなかから膵癌は発見されなかった。60歳代のfollow-up率は40歳以上60歳未満のそれにくらべて有意の低値をとった。早期膵癌の見逃しを少なくするためには,今後,60歳代を中心とする患者のfollow-up率をさらに高めることが必要である。
Abstract Alternative To find an effective mass screening method for detecting early pancreatic cancer among asymptomatic populations and patients with vague abdominal symptoms, a prospective study was attempted on 1748 patients who came to Medical Clinic of Misasa Branch Hospital, Okayama University Medical School mostly for a routine annual chek-up from June 1, 1986 through June 30, 1990. These patients underwent first-step screeing tests including serum amylase, elastase I and routine abdominal ultrasonography (US). Consequently 155 patients (8.9% of the total 1748 patients) showed abnormal findings and underwent secondstep tests including US, ERCP and computed tomography. Final diagnosis was early pancreatic cancer in one patient and advanced pancreatic cancer in four. Three of the 5 patients with pancreatic cancer were in their sixties. Detection rate of pancreatic cancer (0.29%) in this series was satisfactory as compared with the results of previous reports with US alone. The rate of second-step examination increased with age. Six hundred and forty-one patients (36.7% of the 1748 patients) underwent follow-up examinations more than one year after the previous test. No pancreatic cancer was detected in the 641 patients. The rate of follow-up examination in patients in their sixties was significantly lower than in those in their forties or fifties. It is important to improve the follow-up rate in patients in their sixties, because they are at a high risk for pancreatic cancer as suggested by the present study.
Keywords 膵集検 (Mass screening for pancreatic cancer) 膵癌の早期診断 (Early diagnosis of pancreatic cancer) 早期膵癌 (Small pancreatic cancer)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 5
End Page 10
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313927
JaLCDOI 10.18926/11668
Title Alternative カンジダ特異的IgG(4)抗体と気管支喘息
FullText URL 062_001_004.pdf
Author Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Takatori, Akimasa| Okuda, Hiroyuki| Harada, Hideo|
Abstract Serum levels of Candida-specific IgG(4) antibodies were examined in 66 patients with bronchial asthma, relating to patient age and asthma severity. 1. The levels of Candida-specific IgG(4) antibodies were the highest in patients with 60+years of age, compared to the levels in cases with 0-39 and 40-59 years of age. 2. In cases with 40-59 years of age, the levels of Candida-specific IgG(4) were significantly higher in cases with long-term steroid therapy (severe intractable asthma) than in cases without steroid regimen. The results suggest that increased levels of Candida-specific IgG(4) were observed in relation to patient age and asthma severity.
Abstract Alternative 66例の気管支喘息症例を対象に,血清中カンジダ特異的lgG(4)抗体を測定し,その血中レベルと年齢および喘息の重症度との関連について検討を加えた。1.血清カンジダ特異的IgG(4)値は,0~39才,40~59才の年齢層にくらべ,60才以上の年齢層において高く,年齢によりその値が変動することが 示唆された。2.40~59才の年齢層では,血清カンジダ特異的IgG(4)は,ステロイド非使用例にくらべ,ステロイド依存性重症難治性喘息症例で有意の高値を示し,この年齢層では,カンジダ特異的IgG(4)抗体がその発症病態に関連している可能性が示唆された。以上,カンジダ特異的IgG(4)抗体の上昇は,高年齢層の症例(60才以上)では全般的に,また40~59才の年齢層で重症型喘息症例において観察されることが明らかにされた。
Keywords Candida (カンジダ) Sepcific IgG(4) (特異的IgG(4)) Bronchial asthma (気管支喘息) Aging (加齢) Asthma severity (喘息重症度)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 1
End Page 4
ISSN 0913-3771
language 英語
File Version publisher
NAID 120002313495
JaLCDOI 10.18926/11669
Title Alternative A case report of appendiceal calculus presented as abdominal tumor
FullText URL 061_138_142.pdf
Author Suzuka, Ichio| Hirai, Shunichi| Morisue, Shinhachi| Soda, Mitsuhiro| Komoto, Yoshiaki| Yorozu, Hidenori|
Abstract 虫垂結石は虫垂炎手術例の数%に見られるに過ぎないが,穿孔性腹膜炎などの重篤な炎症を招く可能性が高いことで知られている。自験例は41才の女性で,右下腹部腫瘤を主訴として来院した。画像診断で腫瘤は虫垂に連続し,内部に石灰化を認めたが,腫瘤が硬く,虫垂炎症状が軽微であったことから,虫垂原発腫瘍を疑い手術を行ったところ,虫垂膿瘍を併発した虫垂結石であった。本症が自験例のように触知可能な腹部腫瘤を形成することは比較的まれである。
Abstract Alternative Appendiceal calculi are found in the only several percent of patients with appendicitis and have been known to be complicated in severe appendicitis or perforated peritonitis. We reported a 41-year-old female patient, whose initial symptom was right lower abdominal tumor of insidious growing. Abdominal examination revealed a small fist sized hard mass in the right lower abdomen with slight tenderness, and free of rebound tenderness and muscle defence. Abdominal ultrasonography and computed tomography showed that the tumor had continuity with appendix and contained calcification inside. Accordingly, she was diagnosed to have an appendiceal neoplasm and operated on. Post-operative diagnosis was appendiceal abscess with a calculus, 1 centimeter in diameter. It is rare that appendiceal calculi manifest a palpable abdominal tumor like this case.
Keywords 虫垂結石 (Appendiceal calculus) 腹部腫瘤 (Abdominal tumor) 急性虫垂炎 (Acute appendicitis)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 138
End Page 142
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002314032
JaLCDOI 10.18926/11670
Title Alternative A case of atopic asthma characterized by marked neutrophilia in BALF
FullText URL 061_129_133.pdf
Author Kawauchi, Kazuhisa| Mifune, Takashi| Kitani, Hikaru| Sudo, Michiyasu| Tanizaki, Yoshirou| Kataoka, Hisakazu| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Abstract 気管支肺胞洗浄液(BALF)中に高度の好中球の増多が見られ,治療により臨床症状の軽快と共にBALF中の好中球の減少を認めたアトピー型喘息の一例を経験した。経過中5回施行したBALF中の好中球百分率はそれぞれ65.4%,56.2%,42.4%,5.6%,5.6%であり,4回目,5回目では著明な好中球減少を認めた。本症例の如き症例は今後増加することが予想され,その発症病態を含め今後さらに症例を重ねて検討して行く必要があると 考えられた。
Abstract Alternative The clinical course and characteristics of a case with atopic asthma, showing marked neutrophilia in BALF and severe asthma attacks, were observed the frequency of neutrophils in BALF decreased followed by the improvement of her asthma attacks with therapy. The frequency of neutrophils in BALF was 65.4% at the initial stage before the therapy and decreased to 5.6% at attackfree stage after the therapy. The changes in frequency of neutrophils in BALF, obserbed in this case, should be noticed, because the cell in BALF were hardly affected by any treatment.
Keywords アトピー型喘息 (Atopic asthma) 好中球 (Neutrophil) 気管支肺胞洗浄法 (Bronchoaiveolar lavage)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 129
End Page 133
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313690
Author Matsubara, Fumie| Endou, Hiroi| Sudo, Michiyasu| Tanizaki, Yoshiro|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Data or Dataset
JaLCDOI 10.18926/11672
Title Alternative A case of malignant lymphoma of the small intestine
FullText URL 061_134_137.pdf
Author Hirai, Shunichi| Suzuka, Ichio| Morisue, Shinhachi| Soda, Mitsuhiro| Komoto, Yoshiaki| Yorozu, Hidenori|
Abstract 原発性小腸悪性リンパ腫は,術前診断が困難で予後が悪い,比較的希な疾患である。我我の症例は60歳の男性で,右下腹部痛にて来院し,急性虫垂炎の診断で手術を施行した。手術時,回腸末端部より10cm口側に潰瘍性病変を認め,クローン病を疑って回盲部切除を施行した。病理組織検査にて悪性リンパ腫,difuse,medium sized cell typeと診断され,広範回腸切除を含む右記結腸切除及び所属リンパ節郭清を行った。リンパ節転移は認めず,stage I,治癒切除と考えられた。術後7カ月現在,再発の徴候無く外来通院中である。本症は5年生存率22~40%と茅後の悪い疾患であるが,stage I・IIとstage III・IV,治癒切除と非治癒切除の生存率には明かな差があり,早期の診断と根治切除の重要性を示唆している。また本症は,緊急手術を要する場合や自験例のごとく急性虫垂炎の診断で手術を受けることが少なからずあると思われ,根治切除に確信のもてない場合は再手術をためらってはならないと考える。
Abstract Alternative A 60 - year-old man complaining of right lower abdominal pain was sent to the operating room for acute appendicitis. The ileocoecal resection was performed for ulceration of the terminal ileum, which was diagnosed as an intestinal malignant lymphoma histologically. The case, therefore, was re-operated three weeks after the first operation. The right half of colon, and about 70 centimeters of ileum with their regional lymphnodes were resected. The case was revealed as the first stage of clinical classification by Naqvi et al. Up to the present time, 7 months after the first operation, there were no sIgns of reccurence. Intestinal malignant lymphoma somtimes has need to do an emergency oparation, and reoperation should be done without hesitation, if necessary.
Keywords 小腸悪性リンパ腫 (Malignant lymphoma of the small intestine) 小腸悪性腫瘍 (Malignant tumor of the small intestine)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 134
End Page 137
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313492
JaLCDOI 10.18926/11674
Title Alternative Development of stepping measurement device for evaluation of and training in walking
FullText URL 061_123_128.pdf
Author Matsumoto, Shuji| Ochi, Koji| Tanaka, Juntaro| Tachibana, Hideo| Seno, Toshinobu| Harada, Hideo| Tsuboi, Keiichi| Miyake, Hirofumi| Kimura, Ikuro|
Abstract 急性膵炎の回復後その発症原因の検索において発見された小膵癌の3例を報告し,膵炎の発症原因の一つとして膵癌を常に念頭におく必要があることを強調した。またスクリーニング検査および精査において小膵癌を診断する手順について考察を加えた。症例1は初回発作の回復後に,症例2および症例3は再発発作の回復後に急性膵炎の発症原因の検索を目的に紹介された。いずれの症例においても血清腫瘍マーカーは正常植を示し,腹部USおよびCTは腫瘍から尾側の膵管の拡張を示したが腫瘍そのものは描出はできなかった。症例1ではERCP像から膵体部癌を強く疑い,症例2と症例3ではERCP像と細胞診陽性所見から膵頭部癌と確診し,手術を行った。腫瘍の最大径は症例1では0.9cm,症例2では1.5cm,症例3では2.0cmであり,いずれも転移を認めず根治切除可能であった。
Abstract Alternative Although gait training equipment such as the bicycle ergometer and treadmill exists for patients whose walking ability is high, there is no appropriate gait training mehtod or training instrument for patients whose walking ability has become impaired, who often use a cane or walker, etc. in the course of daily life. In the case of gait training for persons whose walking ability involves impaired locomotion, there is always the danger of a fall. Consequently, a caregiver is required, and the effect of the training is cut by half because the patient's anxiety about falling is exacerbated. Slow stepping affords strengthening and balance training of the leg muscles for patients whose walking ability has become low, and walking ability is improved. However,whether such training appropriately carries out stepping and the degree of the effect of such training has not been evaluated. Therefore, we have developed a stepping measturement device that monitors stepping for evaluation and training of walking ability. This system consists of two mat switches for stepping, a measuring circuit for stepping detection, and a book-sized personal computer with a PC card-type AD converter. This system can detect a left or right single stance phase and a double stance phase relative to the ON, OFF condition of the mat switch. After measurement, the following items are analyzed and displayed : ・number of steps, ・average time of double stance phase, ・the average time of single stance phase, and so on. Finally, we measured the stepping of subjects whose walking ability is low, and showed the relationship between daily walking conditions and stepping conditions. The effectiveness of this system was considered in light of the results.
Keywords 小膵癌 (Small pancreatic cancer) 膵癌の早期発見 (Early diagnosis of pancreatic cancer) 急性膵炎 (Acute pancreatitis)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 123
End Page 128
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002313750
Author 三朝分院看護部|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Others
Author 岡山大学医学部附属環境病態研究施設,岡山大学医学部附属病院三朝分院|
Published Date 1990-09
Publication Title 環境病態研報告
Volume volume61
Content Type Others
JaLCDOI 10.18926/11679
Title Alternative Clinical evaluation of new formula included oligopetide as a nitrogen source in surgical patients
Author Soda, Mitsuhiro| Yorozu, Hidenori| Morisue, Sinhachi| Hirai, Shunichi| Suzuka, lchio| Komoto, Yoshiaki| Kajitani, Nobuaki| Yoshizane, Ken| Naniwa, Hiroyuki| Teramoto, Shigeru|
Abstract 窒素源としてdi-,tri-peptideを含有した経腸栄養剤を外科患者に使用した。.この新しい経腸栄養剤は卵白を加水分解したもので,70%がoligopeptideであり,アミノ酸も10%含まれる。糖質はデキストリンで,脂肪の含有量は少なく浸透圧はエレメンタルダイエット(ED)より低い。この製剤を安定期および術後に使用した。アルブミン,rapid turnover proteinの回復がみられ,臓器蛋白の合成が得られた。術後例では3メチルヒスチジンの排泄量は減少せず,異化反応は抑制されなかった。投与量の不足が一つの原因と思われる。副作用の下痢はほとんどみられず,栄養改善効果もあり,有用性が認められた。
Abstract Alternative The clinical usefulness of new enteral formula which is contained di-and tri-peptides as a nitrogen source was evaluated in surgical patients. The enteral nutrition was introduced to stable patients who could not take food orally and postoperative ones who were undertaken upper GI surgery. Adverse effects such as diarrhea or abdomonal distension were not observed. V isceral proteins were improved after administration of this regimen and nutritional status was maintained in all patients. However, high urinary excretion of 3methylhistidine continued in great extent during postopertive period and breakdown of skeletal muscle was not prevented by this nutritional therapy. This might be due to insufficient intake of energy and nitrogen. This new product for enteral nutrition would be safe and useful as enteral nutrition.
Keywords 経腸栄養 (Enteral nutrition) エレメンタルダイエット (Elemental diet) オリゴペプチド (Oligopeptide) 外科栄養 (Surgical nutrition)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 61
End Page 67
ISSN 0913-3771
language 日本語
File Version publisher
JaLCDOI 10.18926/11685
Title Alternative 日本に於ける二酸化炭素泉療法の現況
FullText URL 061_068_072.pdf
Author Komoto, Yoshiaki| Soda, Mitsuhiro| Hirai, Shunichi| Morisue, Shinhachi| Suzuka, Ichio| Yorozu, Hidenori|
Abstract Natural CO(2) springs have been scarcely utilized in Japan, whereas artificial CO(2) bathing has become popular by the introduction of CO(2) tablets and other apparatus for CO(2) water supply. Artificial CO(2) bathing is indicated for degenerative connective tissue disorders such as scleroderma, common stiff and painful shoulders, chronic joint pain, lumbago, and trophic changes due to insufficient peripheral circulation by virtue of the increase of tissue pO(2) and the improvement of tissue perfusion. Artificial CO(2) bathing promotes recovery from fatigue and is beneficial in women whose health has been adversely affected by cold.
Abstract Alternative 日本では,天然の二酸化炭素泉は殆ど利用されていない。一方,CO(2)錠剤,CO(2)給水装置が開発されて人工二酸化炭素泉がよく用いられるようになってきた。皮下組織の酸素分圧の上昇と組織循環の改善という好ましい生理作用により,結合織の退行性変化による慢性障害,すなわち強皮症,関節症,慢性関節痛,腰痛症,および末梢循環障害に伴う組織の栄養障害に適応がある。また,疲労回復を促進し,いわゆる冷え症に好ましく作用する。
Keywords CO(2) -balneotherapy Artificial CO(2) -bathing Tissue pO(2)
Publication Title 環境病態研報告
Published Date 1990-09
Volume volume61
Start Page 68
End Page 72
ISSN 0913-3771
language 英語
File Version publisher
NAID 120002313982