Kunishige, Takahiro Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
A new procedure for the iron-catalyzed synthesis of enamides from ketoximes was developed, and its mechanism was proposed. A unique reduction system, with the concerted use of KI and Na2S2O4, was involved. The reaction exhibited a wide substrate scope and gave good yields in a short reaction time. The procedure is operationally simple and also applicable for the large-scale synthesis.
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|Web of Science KeyUT|
Takahiro Kunishige, Daisuke Sawada, Efficient and practical synthesis of N-acetyl enamides from ketoximes by unique iron catalytic system, Tetrahedron Letters, Volume 60, Issue 24, 2019, Pages 1562-1565, ISSN 0040-4039, https://doi.org/10.1016/j.tetlet.2019.05.006.
Japan Society for the Promotion of Science
|Open Access (Publisher)||
|Open Archive (publisher)||