ID 56676
フルテキストURL
著者
Ghosh, Arjun Division of Parasitology, National Institute of Cholera & Enteric Diseases
Karmakar, Sumallya Division of Parasitology, National Institute of Cholera & Enteric Diseases
Mukherjee, Avik K. Division of Parasitology, National Institute of Cholera & Enteric Diseases
Raj, Dibyendu Division of Parasitology, National Institute of Cholera & Enteric Diseases
Das, Koushik Division of Parasitology, National Institute of Cholera & Enteric Diseases
Sarkar, Srimanti Department of Biochemistry, Bose Institute
Nozaki, T. Department of Parasitology, National Institute of Infectious Diseases, Japan and Graduate School of Life and Environmental Sciences, University of Tsukuba
Ganguly, Sandipan Division of Parasitology, National Institute of Cholera & Enteric Diseases
抄録
Small nuclear Ribonucleo Protein F (snRNP F) is a spliceosomal protein that binds with U1, U2, U4/U6 and U5 small nuclear RNA (snRNA) to form spliceosomal complexes responsible for pre mRNA processing. This study reports the unusual interaction of giardial snRNP F with small nucleolar RNAs (snoRNA) that are responsible for pre rRNA processing. Electrophoretic Mobility Shift Assay was used to demonstrate the interaction of this protein with U3 and U14 class snoRNA of the early branching eukaryote Giardia lamblia. It was also evident from our study that snRNP F in Giardia is evolutionary distinct from its other eukaryotic orthologues.
キーワード
Giardia lamblia
snRNA
snoRNA
U3
U14
発行日
2013
出版物タイトル
Global Journal of Biology, Agriculture & Health Sciences
2巻
3号
出版者
Longdom Publishing
開始ページ
178
終了ページ
184
ISSN
23195584
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
論文のバージョン
publisher
プロジェクト
インド感染症共同研究
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