Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

ラット皮膚細胞の関与する免疫反応への紫外線の影響

高橋 健治 岡山大学医学部第一外科学教室
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抄録
The effect of UV-B radiation on immune responses was evaluated by radiation of rat spleen and skin epidermal cells in vitro. The radiation deteriorated the immune responses without influencing the viability of the irradiated cells. The mitogenic blastognesis of the spleen cells was inhibited. The stimulatory effect of the spleen and skin cells was inhibuted in mixed lymphocyte cultures. The cytotoxicity of spleen cells was decrased. The susceptibility of target skin cells to natural cytotoxicuity was decreased, Therefore, UV-B radiation causes changes in the cell membrane resulting in the inhibition of immune responses.
キーワード
皮膚細胞
免疫反応
紫外線
備考
原著
ISSN
0030-1558
NCID
AN00032489