Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

当院における下部胆管癌手術症例の治療成績

濱野 亮輔 国立病院機構福山医療センター 外科
稲垣 優 国立病院機構福山医療センター 外科
西江 学 国立病院機構福山医療センター 外科
徳永 尚之 国立病院機構福山医療センター 外科
常光 洋輔 国立病院機構福山医療センター 外科
大塚 眞哉 国立病院機構福山医療センター 外科
岩川 和秀 国立病院機構福山医療センター 外科
岩垣 博巳 国立病院機構福山医療センター 外科
園部 宏 中国中央病院 臨床検査科
Thumnail 122_39.pdf 290 KB
抄録
We experienced 20 patients with distal bile duct carcinoma from May, 1997 to December, 2007. The male/female ratio was 11/9 and the average age was 69.6 years. The operative procedures were as follows : pancreaticoduodenectomy (PD), 9 ; pyrolus preserving pancreaticoduodenectomy (PPPD), 8 ; subtotal stomach preserving pancreaticoduodenectomy (SSPPD), 2 and hepatico-jejunostomy without resection, 1. We performed a clinicopathological study on 16 patients with distal bile duct carcinoma, excluding 3 operation-related deaths and 1 unresectable case. The cumulative survival rate was 70% at 3 years and 11% at 5 years. The 3-year survival rates at fStageII, fStageIVa and fStageIVb were 100%, 80% and 0%, respectively. Log-rank analysis revealed that pathological pancreatic and duodenal invasion and curative resectability may be prognostic factors, while lymph node metastasis and perineural and stump invasion did not affect prognosis. Six recurrences in the 11 curative resection cases (54.5%) were observed ; therefore, postoperative systemic chemotherapy is warranted to curtail recurrence in advanced distal bile duct carcinoma.
キーワード
下部胆管癌 (distal bile duct carcinoma)
手術 (operation)
予後規定因子 (independent prognostic factors)
備考
原著
ISSN
0030-1558
NCID
AN00032489
DOI