Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

異臭魚の発生と石油成分の食物連鎖 第4編 n-パラフィンの生体膜への作用

三宅 与志雄 岡山大学医学部公衆衛生学教室
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The effects of n-paraffin on the oxidative phosphorylation of mitochondria and K(+) compartmentation of mitochondria and erythrocyte membrane were studied and the following results were obtained. 1) The effects of n-paraffin on decoupling action of oxidative phosphorylation were observed in the order of C(6), C(7), C(8)>C(9)>C(10)>C(11)>C(12)>C(13)>C(14)>C(15). 2) The effects of n-paraffin on release of K(+) from the mitochondria were observed of C(7)>C(8)>C(9)>C(10)>C(6)>C(11)>C(12)>C(13)>C(15). 3) The release of K(+) by n-paraffin on the erythrocytes were also observed in the order of C(6)>C(7)>C(8)>C(9)>C(10)>C(11)>C(12)>C(13)>C(14)>C(15). 4) The effects of n-paraffin, monocarboxylic acid and dicarboxylic acid of carbon number 6 and 8 on decoupling of oxidative phosphorylation of mitochondria were observed in the order of n-paraffin>monocarboxylic acid>dicarboxylic acid and those of carbon number 10 were observed in the order of monocarboxylic acid>dicarboxylic acid>n-paraffin.