(1) Mucoprotein level in serum and agglutination reaction by Rose for rheumatoid arthritis were measured in 40 cases of rheumatoid arthritis, cancer, pulmonary tuberculosis or liver disease (mostly acute hepatitis). A raised titer of mucoprotein was often observed in cancer, and a marked rise in agglutination titer was often proved in rheumatoid arthritis. But no significant correlation was proved between the serum mucoprotein level and agglutination test
in patients. (2) [n animal experiment an inereased agglutination titer was caused by sensitization with egg albumin, Arthus' s phenomenon, anaphylactic, shock, thermal spring bath, X-ray irradiation, blocking of reticuloendothelial system, liver injuries, injection of A. C. T. H., adrenaline, atropin or pilocarpin. A simultaneoas rise in serum mucoprotein level was observed after
sensitization, thermal bath, X-ray irradiation, administmtion of chloroform, injection of toxic agents to vegetative nerve system. And a significant positive linear correlation was proved between the serum mucoprotein level and agglutination titer in the animal experiment on the whole. But a dissociation in this relation was observed during anaphylactic shok. Namely serum mucoprotein level tended to fall soon after the reinjection, while the agglutination titer rose higher temporarily and then both showed a tendency to decrease.