Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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ラット腹腔肥満細胞に関する研究 第2報 : 肥満細胞のCa(2+)取りこみに対するBSAの影響について

谷崎 勝朗 岡山大学三朝分院内科
田中 淳太郎 岡山大学三朝分院内科
駒越 春樹 岡山大学三朝分院内科
森永 寛 岡山大学三朝分院内科
岸本 卓巳 岡山大学第2内科
木村 郁郎 岡山大学第2内科
Townley Robert G. クレイトン大学内科
抄録
To examine the effect of BSA on the cell surface of mast cells, the (45)Ca influx was observed in mast cells from actively sensitized rats and also in cells passively sensitized with IgE-containing serum before or after purification by BSA. The mast cells from actively sensitized rats showed a marked increase in the (45)Ca uptake with stimulation by ovalbumin. The value of (45)Ca uptake by the cells was 1495 ± 104 cpm / 10(5) cells. The uptake of (45)Ca by mast cells passively sensitized before or after separation through BSA was also increased in response to ovalbumin, although the degree of 45Ca uptake by the latter showed marked variation. These results may suggest that BSA affects mast cell surface when the cells are sensitized after separation by BSA.
備考
原著論文 (Original Papers)
ISSN
0369-7142
NCID
AN00032853