Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Correlation between clinical features of asthma and computed tomographic findings of nose and maxillary sinus

御舩 尚志 岡山大学医学部附属病院三朝分院内科
山本 和彦 岡山大学医学部附属病院三朝分院内科
岩垣 尚史 岡山大学医学部附属病院三朝分院内科
岡本 誠 岡山大学医学部附属病院三朝分院内科
柘野 浩史 岡山大学医学部附属病院三朝分院内科
芦田 耕三 岡山大学医学部附属病院三朝分院内科
光延 文裕 岡山大学医学部附属病院三朝分院内科
保崎 泰弘 岡山大学医学部附属病院三朝分院内科
谷崎 勝朗 岡山大学医学部附属病院三朝分院内科
多田 慎也 岡山大学医学部第二内科
原田 実根 岡山大学医学部第二内科
抄録
Extent of nasal and maxillary mucosa lesion was estimated in 26 asthmatics using computed tomographic scan in relation to clinical features of the disease. 1. No significant differences were present in nasal mucosal thickening between atopic and non-atopic subjects. No significant differences were also present in occupancy rate of mucosa in maxillary sinuses between the two asthma types. 2. Nasal mucosal thickening was not significant different between subjects with steroid-dependent intractable asthma (SDIA) and those without SDIA. Maxillary mucosal lesions were more extensive in subjects with SDIA than in those without SOIA. However, no significant differences were observed in occupancy rate between the two types. 3. No significant differences were observed in nasal mucosal thickenings between in subjects with and without aspirin-induced asthma (AlA). Although maxillary mucosa lesion in subjects with AlA was more extensive than that in those without AlA, the differences was not significant. 4. There was not any correlation between nasal mucosal thickening and amount of expectoration per day. However, significant differences were observed in maxillary sinus lesion between subjects with less amount (<50mℓ/day) and those with large amount of expectoration (100mℓ/day≦)(p<0.002), and between subjects with moderate amount (50-99mℓ/ day) and those with large amount of expectoration (p<0.002). The results might suggest that in asthmatics with large amount of expectoration, sinus diseases affect pathophysiology of asthma, and asthmatics with large amount of expectoration should have therapy for sinus disease to improve asthmatic status.
キーワード
bronchial asthma
sinusitis
nasal disease
CT scan
expectoration
ISSN
0918-7839
NCID
AN10430852