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タイトル(別表記) A prospective cohort study to define the clinical and pathological features of lung cancers harboring HER2 gene aberrations (the HER2-CS Study) and a phase II study of trastuzumab emtansine (recombinant) in patients with HER2-positive non-small cell lung cancer who recurred, progressed after standard chemotherapy, or were primarily refractory to standard chemotherapy
フルテキストURL 127_127.pdf
著者 木浦 勝行| 堀田 勝幸| 佐藤 晃子| 大橋 圭明| 二宮 崇| 南 大輔| 田端 雅弘| 久保 寿夫| 加藤 有加| 平田 泰三|
キーワード 臨床研究中核病院 国立研究開発法人日本医療研究開発機構 文部科学省橋渡し研究加速ネットワークプログラム HER2-CS study trastuzumab emtansine
備考 特集(Feature Articles)
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
127巻
2号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 127
終了ページ 132
ISSN 0030-1558
NCID AN00032489
資料タイプ 学術雑誌論文
関連URL isVersionOf https://doi.org/10.4044/joma.127.127
言語 Japanese
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.127.127
NAID 130005096256
Eprints Journal Name joma
参考文献 1) Ohnoshi T, Hiraki S, Kawahara S, Yamashita H, Yonei T, Ishii J, Egawa T, Kozuka A, Hiraki Y, Kimura I : Randomized trial comparing chemotherapy alone and chemotherapy plus chest irradiation in limited stage small cell lung cancer : a preliminary report. Jpn J Clin Oncol (1986) 16, 271-277. 2) Pignon JP, Arriagada R, Ihde DC, Johnson DH, Perry MC, Souhami RL, Brodin O, Joss RA, Kies MS, Lebeau B, Onoshi T, Østerlind K, et al. : A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med (1992) 327, 1618-1624. 3) Hotta K, Matsuo K, Ueoka H, Kiura K, Tabata M, Tanimoto M : Meta-analysis of randomized clinical trials comparing Cisplatin to Carboplatin in patients with advanced non-small-cell lung cancer. J Clin Oncol (2004) 22, 3852-3859. 4) Segawa Y, Kiura K, Takigawa N, Kamei H, Harita S, Hiraki S, Watanabe Y, Sugimoto K, Shibayama T, Yonei T, Ueoka H, Takemoto M, et al. : Phase III trial comparing docetaxel and cisplatin combination chemotherapy with mitomycin, vindesine, and cisplatin combination chemotherapy with concurrent thoracic radiotherapy in locally advanced non-small-cell lung cancer : OLCSG 0007. J Clin Oncol (2010) 28, 3299-3306. 5) EBMの手法による肺癌診療ガイドライン2014年版, 日本肺癌学会編, 金原出版, 東京 (2014) . 6) Kuyama S, Hotta K, Tabata M, Segawa Y, Fujiwara Y, Takigawa N, Kiura K, Ueoka H, Eguchi K, Tanimoto M : Impact of HER2 gene and protein status on the treatment outcome of cisplatin-based chemoradiotherapy for locally advanced non-small cell lung cancer. J Thorac Oncol (2008) 3, 477-482. 7) Mazières J, Peters S, Lepage B, Cortot AB, Barlesi F, Beau-Faller M, Besse B, Blons H, Mansuet-Lupo A, Urban T, Moro-Sibilot D, Dansin E, et al. : Lung cancer that harbors an HER2 mutation : epidemiologic characteristics and therapeutic perspectives. J Clin Oncol (2013) 31, 1997-2003. 8) Suzuki M, Shiraishi K, Yoshida A, Shimada Y, Suzuki K, Asamura H, Furuta K, Kohno T, Tsuta K : HER2 gene mutations in non-small cell lung carcinomas : Concurrence with her2 gene amplification and her2 protein expression and phosphorylation. Lung Cancer (2015) 87, 14-22. 9) Remillard S, Rebhun LI, Howie GA, Kupchan SM : Antimitotic activity of the potent tumor inhibitor maytansine. Science (1975) 189, 1002-1005. 10) Lewis Phillips GD, Li G, Dugger DL, Crocker LM, Parsons KL, Mai E, Blättler WA, Lambert JM, Chari RV, Lutz RJ, Wong WL, Jacobson FS, et al. : Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res (2008) 68, 9280-9290. 11) Weiler D, Diebold J, Strobel K, Aebi S, Gautschi O : Rapid response to trastuzumab emtansine in a patient with HER2-driven lung cancer. J Thorac Oncol (2015) 10, e16-17.
著者 二宮 崇|
発行日 2013-09-30
出版物タイトル
資料タイプ 学位論文