start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=除鉄による癌幹細胞を標的とする新しい治療戦略 kn-title=Iron depletion is a novel therapeutic strategy to target cancer stem cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NinomiyaTakayuki en-aut-sei=Ninomiya en-aut-mei=Takayuki kn-aut-name=二宮卓之 kn-aut-sei=二宮 kn-aut-mei=卓之 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=1 article-no= start-page=19 end-page=23 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Surgically treated Zenker’s diverticulum： Diverticulectomy and cricopharyngeal myotomy kn-title=憩室切除と輪状咽頭筋切開術を行ったZenker憩室症の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Zenker's diverticulum is a very rare disease among gastorointestinal diverticulum. We report a case of Zenker's diverticulum successfully treated with diverticulectomy and cricophalyngial myotomy. A 71-year-old male complained of aspirating water for two years. He was diagnosed as Zenker's diverticulum. Due to his severe symptoms, the operation was performed in an open-neck approach. The left recurrent laryngeal nerve was identified and preserved. An incision was made in the diverticulum wall, and the internal diameter of normal cervical esophagus was measured. The diverticulum was then excised with an automatic suture device in the minor axis direction of the esophagus. A cricopharyngeal myotomy was conducted, because this muscle was fibrotic and stiffened. The patient's symptoms disappeared after the operation. Diverticulectomy and cricopharyngeal myotomy through an open-neck approach is a safe and reliable method that follows, direct access to the diverticulum and recurrent laryngeal nerve. en-copyright= kn-copyright= en-aut-name=NinomiyaTakayuki en-aut-sei=Ninomiya en-aut-mei=Takayuki kn-aut-name=二宮卓之 kn-aut-sei=二宮 kn-aut-mei=卓之 aut-affil-num=1 ORCID= en-aut-name=KanayaNobuhiko en-aut-sei=Kanaya en-aut-mei=Nobuhiko kn-aut-name=金谷信彦 kn-aut-sei=金谷 kn-aut-mei=信彦 aut-affil-num=2 ORCID= en-aut-name=KatsudaKoh en-aut-sei=Katsuda en-aut-mei=Koh kn-aut-name=勝田浩 kn-aut-sei=勝田 kn-aut-mei=浩 aut-affil-num=3 ORCID= en-aut-name=TanakayaKohji en-aut-sei=Tanakaya en-aut-mei=Kohji kn-aut-name=田中屋宏爾 kn-aut-sei=田中屋 kn-aut-mei=宏爾 aut-affil-num=4 ORCID= en-aut-name=AokiHideki en-aut-sei=Aoki en-aut-mei=Hideki kn-aut-name=青木秀樹 kn-aut-sei=青木 kn-aut-mei=秀樹 aut-affil-num=5 ORCID= en-aut-name=TakeuchiHitoshi en-aut-sei=Takeuchi en-aut-mei=Hitoshi kn-aut-name=竹内仁司 kn-aut-sei=竹内 kn-aut-mei=仁司 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構岩国医療センター　外科 affil-num=2 en-affil= kn-affil=国立病院機構岩国医療センター　外科 affil-num=3 en-affil= kn-affil=国立病院機構岩国医療センター　外科 affil-num=4 en-affil= kn-affil=国立病院機構岩国医療センター　外科 affil-num=5 en-affil= kn-affil=国立病院機構岩国医療センター　外科 affil-num=6 en-affil= kn-affil=国立病院機構岩国医療センター　外科 en-keyword=Zenker憩室（Zenker’s diverticulum） kn-keyword=Zenker憩室（Zenker’s diverticulum） en-keyword=輪状咽頭筋切開術（cricopharyngeal myotomy） kn-keyword=輪状咽頭筋切開術（cricopharyngeal myotomy） en-keyword=頚部アプローチ（open-neck approach） kn-keyword=頚部アプローチ（open-neck approach） citation=1) 井手博子, 押淵英晃, 杉山明義 : 食道憩室症の病態と治療. Current Therapy（1985）3, 669-675. citation=2) 中村　努, 井手博子 : 食道憩室. 臨消内科（2000）15, 749-755. citation=3) 丹黒　章, 吉野茂文, 安部俊弘, 林　秀知, 岡　正朗 : 食道憩室に対する手術. 手術（2002）56, 1733-1738. citation=4) 大杉治司, 藤原有史, 綛野　進, 高田信康, 竹村雅至, 木下博明 : Zenker憩室に対する輪状咽頭筋切開術. 手術（2002）56, 1518-1522. citation=5) 小熊潤也, 小澤壯治, 北川雄光, 才川義朗, 安藤暢敏, 北島政樹 : 咽頭食道憩室（Zenker憩室）の手術症例における臨床的特徴ならびに治療法についての検討. 日消外会誌（2004）37, 619-624. citation=6) 川村弘之, 片岡　誠, 桑原義之, 呉山泰進, 岩田　宏, 篠田憲幸, 加島健利, 佐藤篤司, 服部浩次, 中野浩一郎, 正岡　昭 : Zenker憩室の1手術例. 日消外会誌（1993）26, 2166-2170. citation=7) Colombo-Benkmann M, Unruh V, Krieglstein C, Senninger N : Cricopharyngeal Myotomy in the Treatment of Zenker's Diverticulum. J Am Coll Surg (2003) 196, 370-378. citation=8) Chiari C, Yeganehfar W, Scharitzer M, Mittlbock M, Armbruster C, Roka R, Fugger R, Wenzl E, Pokieser P, Bischof G : Significant symptomatic relief after transoral endoscopic staple-assisted treatment of Zenker's diverticulum. Surg Endosc (2003) 17, 596-600. citation=9) Peracchia A, Bonavina L, Narne S, Segalin A, Antoniazzi L, Marotta G : Minimally Invasive Surgery for Zenker Diverticulum : Arch Surg (1998) 133, 695-700. citation=10) Scher RL, Richtsmeier WJ : Lonr-term Experience With Endoscopic Staple-Assisted Esophagodiverticulostomy for Zenker's Diverticulum. Laryngoscope (1998) 108, 200-205. citation=11) Busaba NY, Ishoo E, Kieff D : Open Zenker's Diverticulectomy Using Staplling Techniques. Ann Otol Rhinol Laryngol (2001) 110, 498-501. citation=12) Barthlen W, Feussner H, Hannig C, Holscher AH, Siewert JR : Surgical Therapy of Zenker's Diverticulum : Low Risk and High Efficiency. Dysphagia (1990) 5, 13-19. END start-ver=1.4 cd-journal=joma no-vol=126 cd-vols= no-issue=1 article-no= start-page=35 end-page=38 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of colon lipoma presenting with intussusception kn-title=腸重積で発症した結腸脂肪腫の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　An 84-year-old man, who had been found to have a submucosal tumor in the ascending colon two years before, was admitted to our hospital for right lower quadrant abdominal pain and melena. An abdominal computed tomography (CT) scan showed intussusception in the ascending colon, resulting from a fat-density tumor. The intussusception was located by colonoscopy. Since the colonic tumor was enlarged in comparison with two years ago and had an ulcer at the top of the tumor, there was the possibility of malignancy and recurrence of intussusception. He underwent a laparoscopy-assisted right colectomy with lymph node dissection. Pathologically, the tumor of the ascending colon was a benign lipoma. en-copyright= kn-copyright= en-aut-name=NinomiyaTakayuki en-aut-sei=Ninomiya en-aut-mei=Takayuki kn-aut-name=二宮卓之 kn-aut-sei=二宮 kn-aut-mei=卓之 aut-affil-num=1 ORCID= en-aut-name=OjimaYasutomo en-aut-sei=Ojima en-aut-mei=Yasutomo kn-aut-name=小島康知 kn-aut-sei=小島 kn-aut-mei=康知 aut-affil-num=2 ORCID= en-aut-name=HaranoMasao en-aut-sei=Harano en-aut-mei=Masao kn-aut-name=原野雅生 kn-aut-sei=原野 kn-aut-mei=雅生 aut-affil-num=3 ORCID= en-aut-name=OhnoSatoshi en-aut-sei=Ohno en-aut-mei=Satoshi kn-aut-name=大野聡 kn-aut-sei=大野 kn-aut-mei=聡 aut-affil-num=4 ORCID= en-aut-name=ShiozakiShigehiro en-aut-sei=Shiozaki en-aut-mei=Shigehiro kn-aut-name=塩崎滋弘 kn-aut-sei=塩崎 kn-aut-mei=滋弘 aut-affil-num=5 ORCID= en-aut-name=NinomiyaMotoki en-aut-sei=Ninomiya en-aut-mei=Motoki kn-aut-name=二宮基樹 kn-aut-sei=二宮 kn-aut-mei=基樹 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=2 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=3 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=4 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=5 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=6 en-affil= kn-affil=広島市立広島市民病院　外科 en-keyword=結腸脂肪腫（lipoma of the colon） kn-keyword=結腸脂肪腫（lipoma of the colon） en-keyword=腸重積（intussusception） kn-keyword=腸重積（intussusception） en-keyword=腹腔鏡下手術（laparoscopic surgery） kn-keyword=腹腔鏡下手術（laparoscopic surgery） citation=1) Helwig EB : Benign tumor of the large intestine. Incidence and distribution. Surg Gynecol Obstet (1943) 76, 419-426. citation=2) 正岡一良, 中村孝志 : 大腸良性腫瘍, 臨床的事項. 日臨(1988)46, 348-355. citation=3) 藤野啓一, 長谷和生, 森田大作, 宇都宮勝之, 渡邉千之, 山本哲久, 望月英隆 : 大腸脂肪腫23例の臨床的検討. 日臨外会誌(1999)60, 1737-1740. citation=4) 佐藤　洋, 矢島和人, 冨田　広, 松澤岳晃, 小海秀央 : 腸重積を併発した腸管原発脂肪腫に対する腹腔鏡補助下切除の2例. 日臨外会誌(2009)70, 3061-3065. citation=5) 梅原松臣, 高井　淳, 有馬保生, 木内博之, 内藤委仲, 吉村和泰, 横井公良, 恩田昌彦 : 横行結腸脂肪腫の1例. 日消外会誌(1990)23, 1937-1941. citation=6) 笠間和典, 加納宣康, 山田成寿, 草薙　洋, 渡井　有, 武士昭彦 : 腸重積をきたした横行結腸脂肪腫に対して腹腔鏡下手術を施行した1例. 日臨外会誌(1999)60, 2954-2958. citation=7) 丸山　聡, 田中典生, 下田　聡, 武田信夫, 小山俊太郎, 岡本春彦, 畠山勝義 : 腸重積をきたした下行結腸脂肪腫に腹腔鏡下手術を施行した1例. 新潟医会誌 (2004) 118, 217-222. citation=8) 前山　良, 八谷泰孝, 佐古達彦, 福山時彦, 平野　豊 : Ｓ状結腸脂肪腫に起因した成人逆行性腸重積症の1例. 日臨外会誌(2008)69, 100-104. citation=9) 金川泰一朗, 田中屋宏爾, 金澤　卓, 村田　宏 : 成人腸重積症で発見された潰瘍をともなう上行結腸脂肪腫の1例. 日本大腸肛門病会誌(2008)61, 81-84. citation=10) 林　雅規, 瀬山厚司, 原田剛佑, 井口智浩, 守田知明 : 術前CT検査が有用であった腸重積を呈した結腸脂肪腫の一切除例. 山口医学(2009)58, 85-89. citation=11) 猪口晃一, 長畑洋司, 今中洋子 : 大腸脂肪腫の1例. 医研究(1987)48, 101-105. citation=12) 西原修一郎, 牟田俊明, 小田原恵二 : 内視鏡的ポリペクトミーにより摘出した大腸脂肪腫の1例-本邦報告例の文献的考察-. 日消誌(1984)26, 79-83. citation=13) 柴田佳久, 加藤岳人, 鈴木正臣, 尾上重巳, 長澤圭一, 吉原　基 : 当院における結腸脂肪腫の検討-治療方針の面から-. 日消外会誌(2006)39, 1361-1367. citation=14) 小熊潤也, 田村　光, 青木真彦, 細田　桂, 城戸　啓, 夏　錦言, 雨宮　哲 : 成人腸重積の原因となった大腸lipomatous tumorに対し腹腔鏡補助下手術を施行した1例. 日消外会誌(2007)40, 1955-1959. citation=15) 福田直人, 土用下和之, 丸野　要, 山川達郎 : 腸重積をきたしたＳ状結腸脂肪肉腫の1例. 日臨外会誌(2004)65, 429-432. citation=16) 杉本起一, 永仮邦彦, 菅野雅彦, 杉山和義, 津村秀憲, 福永正氣 : 腸重積を発症した巨大横行結腸脂肪腫の1例. 日外科系連会誌(2009)34, 238-242. END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=3 article-no= start-page=239 end-page=242 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of appendiceal diverticulum resected by laparoscopic surgery with preoperative diagnosis of appendiceal tumor kn-title=虫垂腫瘍と術前診断し腹腔鏡下手術を行った虫垂仮性憩室症の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Appendiceal diverticulum is rare. We encountered a case of appendiceal diverticulum with chronic appendicitis. A 56-year-old man presented to our hospital with right lower abdominal pain. An abdominal computed tomography (CT) scan showed swelling of the appendix body and the wall thickness of the base of the appendix. Due to the possibility of appendiceal tumor, we performed a laparoscopy-assisted ileocecal resection with lymph node dissection. The appendix had a diverticulum with chronic inflammation, but it did not have a neoplastic lesion. en-copyright= kn-copyright= en-aut-name=NinomiyaTakayuki en-aut-sei=Ninomiya en-aut-mei=Takayuki kn-aut-name=二宮卓之 kn-aut-sei=二宮 kn-aut-mei=卓之 aut-affil-num=1 ORCID= en-aut-name=OjimaYasutomo en-aut-sei=Ojima en-aut-mei=Yasutomo kn-aut-name=小島康知 kn-aut-sei=小島 kn-aut-mei=康知 aut-affil-num=2 ORCID= en-aut-name=HaranoMasao en-aut-sei=Harano en-aut-mei=Masao kn-aut-name=原野雅生 kn-aut-sei=原野 kn-aut-mei=雅生 aut-affil-num=3 ORCID= en-aut-name=OhnoSatoshi en-aut-sei=Ohno en-aut-mei=Satoshi kn-aut-name=大野聡 kn-aut-sei=大野 kn-aut-mei=聡 aut-affil-num=4 ORCID= en-aut-name=ShiozakiShigehiro en-aut-sei=Shiozaki en-aut-mei=Shigehiro kn-aut-name=塩崎滋弘 kn-aut-sei=塩崎 kn-aut-mei=滋弘 aut-affil-num=5 ORCID= en-aut-name=NinomiyaMotoki en-aut-sei=Ninomiya en-aut-mei=Motoki kn-aut-name=二宮基樹 kn-aut-sei=二宮 kn-aut-mei=基樹 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=2 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=3 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=4 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=5 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=6 en-affil= kn-affil=広島市立広島市民病院　外科 en-keyword=虫垂憩室症（appendiceal diverculum） kn-keyword=虫垂憩室症（appendiceal diverculum） en-keyword=腹腔鏡手術（laparoscopic surgery） kn-keyword=腹腔鏡手術（laparoscopic surgery） en-keyword=虫垂腫瘍（appendiceal tumor） kn-keyword=虫垂腫瘍（appendiceal tumor） END