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ID 16803
Eprint ID
16803
フルテキストURL
Thumnail 94_503.pdf 665 KB
タイトル(別表記)
A study of the extramedullary hemopoiesis in adult mouse liver relating to age and sex.
著者
森 将晏 岡山大学医学部第一病理学教室
切塚 敬治 岡山大学医学部第一病理学教室
中本 周 岡山大学医学部第一病理学教室
定平 吉都 岡山大学医学部第一病理学教室
粟井 通泰 岡山大学医学部第一病理学教室
妹尾 左知丸 重井医学研究所
抄録
Active extramedullary hemopoiesis developed in liver of adult female mice by blood depletion of splenectomized animals. Observations were made on adult C(3)H/He mice, males and females of 6 weeks and 6 months old. The mice were splenectomized and the blood was depleted by 0.6ml/once 20days after splenectomy. The hematocrit value decreased to about 30% at 2days after blood depletion and recovered to near normal level after 10days. No significant differences were observed in the hematocrit value in all the animals observed. Reticulocyte counts increased to 20-28% 4-6days after blood depletion with rapid decrease for the following 4days and then returned to the normal level 25-30days after depletion. The maximum level of reticulocyte counts was highest in aged females(28% ) and lowest in young males(20% ). The number of hemopoietic foci in liver observed on HE stained tissue sections showed a marked difference in each group. Male animals, both young and aged, developed no hemopoietic foci. Females developed many foci in liver, higher values in aged females than young ones. Discussion was made on the reason why aged females developed a large number of foci in liver.
キーワード
肝髄外造血
マウス
週令
発行日
1982-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
94巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
503
終了ページ
507
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/94/5-6/94_5-6_503/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma