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ID 13984
Eprint ID
13984
フルテキストURL
Thumnail 106_199.pdf 581 KB
タイトル(別表記)
Studies on the effect of chemotherapy for multiple myeloma with analysis of bone lesion Part 2. Examination of bone status in multiple myeloma
著者
和泉 健 岡山大学医学部第二内科学教室
抄録
Bone status is the most important finding in multiple myeloma. The changes in the bone were examined by various methods such as elcation test, bone x-ray, bone scintigraphy, urine hydroxyproline and quantitative bone mineral by computed tomography (QCT). The elcation test was evaluated in 87 patients with multiple myeloma and 15 with osteopor-osis. The maximum value of hypocalcemia induced by elcatonin was ≧0.25 mmol/L which was considered as an abnormal response compared with the mormal response. The elcationin test is related to the prevailing rate of osteoclastic bone resorption. Myeloma patients with advanced bone disease (multiple lytic lesion, Mixed type) had a higher abnormal response such as hypercalcemia, hyper ALP, hot of the bone status, urine hydroxproline and decrease in the bone mineral then myeloma patients with slight bone disease (diffuse proliferation type). Moreover, the elcation test can indicate whether the durg will be effective in the hyper calcemia. We conclude that the elcation test is important in the evaluation of the bone resorption as a simple test for the prognosis and followed up the skeletal disease in the patients with multiple myeloma.
キーワード
多発性骨髄腫
骨状態
骨塩量
エルカトニン負荷試験
ハイドロキシプロリン
備考
原著
発行日
1994
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
106巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
199
終了ページ
209
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/106/3-4/106_3-4_199/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma