start-ver=1.4
cd-journal=joma
no-vol=91
cd-vols=
no-issue=1-2
article-no=
start-page=197
end-page=215
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1979
dt-pub=19790228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Search for viral particles in human papillomas
kn-title=人の乳頭腫におけるウイルスの検索
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=By electron microscopy, viral particles were searched for in specimens taken from 3 cases of verruca vulgaris, 2 cases of verruca plana, 2 cases of epidermodysplasia verruciformis, 8 cases of oral papilloma, 2 cases of nasal papilloma, 4 cases of laryngeal papilloma, 2 cases of condyloma acuminatum, 3 cases of bladder papilloma and 1 case of familial intestinal polyposis. Viral particles were detected in all 3 cases of verruca vulgaris, 2 cases of verruca plana, 2 cases of epidermodysplasia verruciformis and in one of 2 cases of condyloma acuminatum. All the viral particles detected in these papillomas were similar morphologically and antigenically and appeared to belong to the papilloma virus group. Vacuolation of cells in the upper epidermal layers was observed histologically in both virus-positive and virus-negative papillomas, and the histologically recognizable characteristics of virus-positive papillomas appeared to be the swelling of the nucleus, peripheral accumulation of the chromatin and clearly distinguished nucleoli in vacuolated cells. These nuclear changes were also observed electron microscopically. Malignant histological features were observed in 1 case of epidermodysplasia verruciformis, 1 case of oral papilloma, 1 case of laryngeal papilloma, and 1 case of familial intestinal polyposis. The significances of these findings are discussed.
en-copyright=
kn-copyright=

en-aut-name=YasuiMasazumi
en-aut-sei=Yasui
en-aut-mei=Masazumi
kn-aut-name=安井正純
kn-aut-sei=安井
kn-aut-mei=正純
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部癌源研究施設ウイルス部門
en-keyword=human papilloma
kn-keyword=human papilloma
en-keyword=electron microscopy
kn-keyword=electron microscopy
en-keyword=virus particles
kn-keyword=virus particles
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1979
dt-pub=19791231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=人の乳頭腫におけるウｨルスの検索
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YasuiMasazumi
en-aut-sei=Yasui
en-aut-mei=Masazumi
kn-aut-name=安井正純
kn-aut-sei=安井
kn-aut-mei=正純
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=乳頭腫
kn-keyword=乳頭腫
END