start-ver=1.4
cd-journal=joma
no-vol=86
cd-vols=
no-issue=11-12
article-no=
start-page=567
end-page=571
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1974
dt-pub=19741230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on biological status in patients with lung cancer
kn-title=肺癌の病態と予後に関する臨床的検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Serum α(1)-acid glycoprotein (α(1)-AG) content, lactic dehydrogenase (LDH) activity, cholinesterase (Ch-Ease) activity, plasma fibrinogen (Fbg) content, hemoglobin content, serum albumin content and erythrocyte sedimentation rate were measured in 117 patients with lung cancer. Significant difference was observed in α(1)-AG as well as Fbg between stage Ⅰ and Ⅱ, in Ch-Ease between stage Ⅱ and Ⅲ and in LDH between stage Ⅲ and Ⅳ. In inoperable cases who did not obtain any clinical improvement during chemotherapy, significant positive correlation was observed between their life spans and α(1)-AG as well as Fbg measured prior to chemtherapy, and as for Ch-Ease negative correlation was observed. More close correlation was obtained between life spans and biological status which was set up following their laboratory data as stated above. Therefore, it seems that biological status are reliable index for estimating life spans of inoperable cases.
en-copyright=
kn-copyright=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=本村郁郎
kn-aut-sei=本村
kn-aut-mei=郁郎
aut-affil-num=1
ORCID=

en-aut-name=OnoshiTaisuke
en-aut-sei=Onoshi
en-aut-mei=Taisuke
kn-aut-name=大熨泰亮
kn-aut-sei=大熨
kn-aut-mei=泰亮
aut-affil-num=2
ORCID=

en-aut-name=TakanoJunko
en-aut-sei=Takano
en-aut-mei=Junko
kn-aut-name=高野純行
kn-aut-sei=高野
kn-aut-mei=純行
aut-affil-num=3
ORCID=

en-aut-name=OsawaHiroshi
en-aut-sei=Osawa
en-aut-mei=Hiroshi
kn-aut-name=大沢汎
kn-aut-sei=大沢
kn-aut-mei=汎
aut-affil-num=4
ORCID=

en-aut-name=YasuharaShozo
en-aut-sei=Yasuhara
en-aut-mei=Shozo
kn-aut-name=安原尚蔵
kn-aut-sei=安原
kn-aut-mei=尚蔵
aut-affil-num=5
ORCID=

en-aut-name=WatanabeTatsuo
en-aut-sei=Watanabe
en-aut-mei=Tatsuo
kn-aut-name=渡部達夫
kn-aut-sei=渡部
kn-aut-mei=達夫
aut-affil-num=6
ORCID=

en-aut-name=SugiyamaMotoharu
en-aut-sei=Sugiyama
en-aut-mei=Motoharu
kn-aut-name=杉山元治
kn-aut-sei=杉山
kn-aut-mei=元治
aut-affil-num=7
ORCID=

en-aut-name=HirakiKiyoshi
en-aut-sei=Hiraki
en-aut-mei=Kiyoshi
kn-aut-name=平木潔
kn-aut-sei=平木
kn-aut-mei=潔
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学平木内科

affil-num=2
en-affil=
kn-affil=岡山大学平木内科

affil-num=3
en-affil=
kn-affil=岡山大学平木内科

affil-num=4
en-affil=
kn-affil=岡山大学平木内科

affil-num=5
en-affil=
kn-affil=岡山大学平木内科

affil-num=6
en-affil=
kn-affil=岡山大学平木内科

affil-num=7
en-affil=
kn-affil=岡山大学平木内科

affil-num=8
en-affil=
kn-affil=岡山大学平木内科
END

start-ver=1.4
cd-journal=joma
no-vol=89
cd-vols=
no-issue=3-4
article-no=
start-page=375
end-page=383
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Immunological studies of the streptococcal preparation, OK-432, on neoplasm Part I. Studies on the host-mediated action of the streptococcal preparation, OK-432, on neoplasm
kn-title=溶連菌剤の腫瘍免疫学的研究 第1編 溶連菌製剤OK-432の宿主を介する抗腫瘍効果の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A study was made on a mode of action of the streptococcal preparation, OK-432, that is rather difficult to elucidate only in terms of its direct effect on tumor cells. Its results are described below: 1) The survival rate of the ICR mice pretreated i.p. with OK-432 was about twice as high as in the nontreated group at 40 days after i.v. inoculation of Ehrlich carcinoma. 2) The survival rate of the C3H mice pretreated i.p. with OK-432 was more prolonged than the rate of nontreated group and post-treated group with OK-432 at 50 days after i.p. inoculation of methylcholanthrene-induced sarcoma. 3) The survival rate of the ICR mice pretreated s.c. with OK-432 was slightly prolonged than the rate of nontreated group at 40 days after i.p. inoculation of Ehrlich carcinoma. 4) The appearance of methylcholanthrene-induced sarcoma of the C3H mice pretreated i.p. with OK-432 was significantly delayed, compared with the nontreated group and the posttreated group at 80 days after injection s.c. with methylcholanthrene. The results stated above lead to the conclusion that OK-432 has a host-mediated antitumor action.
en-copyright=
kn-copyright=

en-aut-name=YasuharaShozo
en-aut-sei=Yasuhara
en-aut-mei=Shozo
kn-aut-name=安原尚蔵
kn-aut-sei=安原
kn-aut-mei=尚蔵
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科
END