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ID 17099
Eprint ID
17099
フルテキストURL
Thumnail 89_375.pdf 1.87 MB
タイトル(別表記)
Immunological studies of the streptococcal preparation, OK-432, on neoplasm Part I. Studies on the host-mediated action of the streptococcal preparation, OK-432, on neoplasm
著者
安原 尚蔵 岡山大学医学部第2内科
抄録
A study was made on a mode of action of the streptococcal preparation, OK-432, that is rather difficult to elucidate only in terms of its direct effect on tumor cells. Its results are described below: 1) The survival rate of the ICR mice pretreated i.p. with OK-432 was about twice as high as in the nontreated group at 40 days after i.v. inoculation of Ehrlich carcinoma. 2) The survival rate of the C3H mice pretreated i.p. with OK-432 was more prolonged than the rate of nontreated group and post-treated group with OK-432 at 50 days after i.p. inoculation of methylcholanthrene-induced sarcoma. 3) The survival rate of the ICR mice pretreated s.c. with OK-432 was slightly prolonged than the rate of nontreated group at 40 days after i.p. inoculation of Ehrlich carcinoma. 4) The appearance of methylcholanthrene-induced sarcoma of the C3H mice pretreated i.p. with OK-432 was significantly delayed, compared with the nontreated group and the posttreated group at 80 days after injection s.c. with methylcholanthrene. The results stated above lead to the conclusion that OK-432 has a host-mediated antitumor action.
発行日
1977-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
89巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
375
終了ページ
383
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/89/3-4/89_3-4_375/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma