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ID 54978
JaLCDOI
フルテキストURL
Thumnail 71_2_105.pdf 2.17 MB
著者
Shinya, Takayoshi Department of Radiology, Okayama University Hospital
Tanaka, Takashi Department of Radiology, Okayama University Hospital
Soh, Junichi Department General Thoracic Surgery, Okayama University Hospital
Matsushita, Toshi Department of Radiology, Okayama University Hospital
Sato, Shuhei Department of Radiology, Okayama University Hospital
Toyooka, Shinichi Department General Thoracic Surgery, Okayama University Hospital 科研費研究者番号
Yoshino, Tadashi Department of Pathology, Okayama University Hospital
Miyoshi, Shinichiro Department General Thoracic Surgery, Okayama University Hospital
Kanazawa, Susumu Department of Radiology, Okayama University Hospital
抄録
We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy.
キーワード
thymic epithelial neoplasm
thymic carcinoma
thymoma
dual-time-point PET/CT
chest CT
Amo Type
Original Article
発行日
2017-04
出版物タイトル
Acta Medica Okayama
71巻
2号
出版者
Okayama University Medical School
開始ページ
105
終了ページ
112
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID