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ID 31139
JaLCDOI
フルテキストURL
著者
Odaka, Koji Okayama University
Eguchi, Katsuto Okayama Univeristy
Kudo, Takafumi Okayama University
抄録

The effects of epidermal growth factor (EGF) on neonatal intestines were examined in the rat. In 5-day-old rats, sucrase, trehalase, alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (gamma-GTP) activities in the small intestines were significantly increased after subcutaneous injection of EGF for 3 days (1 microgram/rat/day). gamma-GTP activity was also accelerated after oral EGF administration (2 micrograms/rat/day). Small intestines of 12-day-old rats injected with EGF for 10 days (1 microgram/rat/day) were significantly heavier than those of controls. These results suggest that EGF influences neonatal growth improving enlargement and functional development of their intestines.

キーワード
epidermal growth factor
neonate
intestine
breast milk
rat
Amo Type
Article
発行日
1994-02
出版物タイトル
Acta Medica Okayama
48巻
1号
出版者
Okayama University Medical School
開始ページ
47
終了ページ
50
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT