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ID 17112
Eprint ID
17112
フルテキストURL
Thumnail 89_449.pdf 11.7 MB
タイトル(別表記)
The experimental study on the thrombin induced disseminanted intravascular coagulation
著者
星合 清輝 岡山大学医学部第二外科
抄録
Disseminated intravascular coagulation (DIC) models were made by intra-aortic infusion of thrombin (50 units/kg. body weight) during 30 minutes in the dogs. Histological study of glomerular fibrin deposition was taken on the specimens which were collected by the renal biopsy. Changes of blood coagulation system and fibrinolytic factors of blood and urine were studied during 120 minutes. These results were summarized as follows: 1. With the light microscope disappearance of all glomerular fibrin deposits were observed 90 minutes after initial infusion. 2. These results suggest that major mechanism of fibrin removal from capillaries was the intravascular fibrinolysis. 3. In addition, as the another mechanism of fibrin removal the transglomerular passage into urinary space was revealed. 4. Urokinase excretion in urine was reduced continuously until the end of experiment. 5. FDP was measured by serial dilution protamine sulfate test for the estimation of fragement X(0) and soluble fibrin monomer complexes.
発行日
1977-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
89巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
449
終了ページ
468
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/89/3-4/89_3-4_449/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma