start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=9-10
article-no=
start-page=809
end-page=818
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1986
dt-pub=19861031
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Toxicity of chlorinated cyclic hydrocarbons I. The effect of administration of chlordane on rat liver and serum, and the levels of certain chemicals in the serum of chlordane workers
kn-title=環式塩素化炭化水素の毒性に関する研究 第1報 テクニカルクロルデン投与ラットの肝,血清成分の変化及び撒布作業従事者の血清検査
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Rats were administered chlordane emulsion orally, and changes in the liver function were studied. The levels of certain chemicals in the serum of chlordane wokers also were determined. The increase in the body weight of rats administered chlordane was suppressed compared to control rats. Liver weights of rats administered chlordane were significantly (p<0.01) greater than those of control rats. Levels of moisture, total lipid, triglycerides and phospholipid per gram liver of rats administered chlordane were significantly (p<0.05) higher than those of control rats. Levels of lipid peroxide of rats administered chlordane were significantly (p<0.05) higher than those of control rats, and increased according to increases in the amount of chlordane administered. Levers of DNP-stimulated ATPase activity in the liver mitochondria of rats administered chlordane were lower than those of control rats. State 4 respiration in the mitochondria of rats administered chlordane was greater than those of control rats. State 3 respiration was the same in both groups. As a result, the respiratory control index (RCI) of administered rats was lower than those of control rats. Levels of triglycerides, total cholesterol and γ-GTP activity in the serum of rats administered chlordane were significantly (p<0.05) higher than those of control rats. Levels of blood suger of rats administered chlordane were significantly (p<0.05) lower than those of control rats. Levels of total cholesterol, triglycerides, activity of CPK and LDH of several tested chlordane wokers were higher than the upper limit of normal persons.
en-copyright=
kn-copyright=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生教室
en-keyword=テクニカルクロルデン
kn-keyword=テクニカルクロルデン
en-keyword=過酸化脂質
kn-keyword=過酸化脂質
en-keyword=中性脂肪
kn-keyword=中性脂肪
en-keyword=酸化的リン酸化反応
kn-keyword=酸化的リン酸化反応
en-keyword=CPK活性
kn-keyword=CPK活性
END

start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=7-8
article-no=
start-page=587
end-page=597
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1986
dt-pub=19860830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effect of chlorinated monoaromatic hydrocarbons on biological membranes(Comparison of the effect of chlorobenzenes and chlorophenols on biomembranes)
kn-title=塩化ベンゼンの生体膜に対する作用 第�W報 分離正常ラット肝ミトコンドリアにおける塩化ベンゼン及び塩化フェノールの作用の比較
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A comparative study on the effect of chlorobenzenes and chlorophenols on mitochondrial membranes was conducted. An increase in chlorine residue from both chlorobenzenes and chlorophenols caused a decrease in respiratory control index (RCI). Chlorophenols acted on biomembranes at a lower concentration than chlorobenzenes. The compounds decreased RCI by increasing state 4 respiration and decreasing state 3 respiration. As the number of chlorine atoms on chlorobenzenes increased, state 3 respiration decreased, causing a decrease in RCI. As the number of chlorine atoms on chlorophenols increased, state 4 respiration increased, causing a decreased in RCI. The amount of potassium released from mitochondrial membranes increased with time after addition of dichlorobenzene and dichlorophenol. A logarithmic increase in potassium release vs. time was observed with dichlorobenzene, and a liner increase in potassium release was observed with dichlorophenol.
en-copyright=
kn-copyright=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生
en-keyword=ミトコンドリア
kn-keyword=ミトコンドリア
en-keyword=酸化的リン酸化反応
kn-keyword=酸化的リン酸化反応
en-keyword=塩化ベンゼン類
kn-keyword=塩化ベンゼン類
en-keyword=塩化フェノール類
kn-keyword=塩化フェノール類
en-keyword=K(＋)遊出作用
kn-keyword=K(＋)遊出作用
END

start-ver=1.4
cd-journal=joma
no-vol=94
cd-vols=
no-issue=11-12
article-no=
start-page=967
end-page=972
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1982
dt-pub=19821230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of chlorinated monoaromatic hydrocarbons on biological membranes (3. Effect of o-dichlorobenzene on rat liver.)
kn-title=塩化ベンゼンの生体膜に対する作用 第�V報 生体内投与における0-ジクロルベンゼンのラット肝に対する作用
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=o-Dichlorobenzene (o-DCB) was emulsified in a 2.5% gum arabic solution and given orally to rats for 60 and 120 days. The effects of o-DCB on rats were compared with control rats given water containing the same percent of gum arabic. The following results were obtained: 1. The livers of rats administered o-DCB were slightly heavier than those of control rats. 2. Triglyceride levels of rats administered o-DCB were higher than those of control rats. The level of triglyceride in rats administered o-DCB tended to increase according to the duration of o-DCB administration. 3. The level of ATP in the liver of rats administered o-DCB was significantly lower than that in the liver of control rats. 4. The respiratory control of liver mitochondria of rats administered o-DCB decreased in state3 respiration, and increased in state4 respiration. The respiratory control index of the liver mitochondria decreased after o-DCB was given orally to rats, and it was observed that the longer the period administration was, the lower the respiratory control index was.
en-copyright=
kn-copyright=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生教定
en-keyword=0-ジクロルベンゼン
kn-keyword=0-ジクロルベンゼン
en-keyword=トリグリセライド
kn-keyword=トリグリセライド
en-keyword=脂質過酸化
kn-keyword=脂質過酸化
en-keyword=ATP
kn-keyword=ATP
en-keyword=酸化的リン酸化
kn-keyword=酸化的リン酸化
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=5-6
article-no=
start-page=537
end-page=541
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effect of chlorinated mono aromatic hydrocarbons on biological membranes. (1. The effect of various concentrations of chlorinated mono aromatic hydrocarbons on the K(+)release of normal isolated rat liver mitochondria)
kn-title=塩化ベンゼンの生体膜に対する作用 第II報 分離正常ラット肝ミトコンドリアにおける各種濃度による塩化ベンゼンのK(+)遊出作用
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The effect of mono-, di-, tri- and tetra-chlorinated benzene on K(+)release from rat liver mitochondria was determined. The following results were obtained: 1) There were differences between the isomer of dichlorobenzenes on the K(+)release and increase in the K(+)release was in the order of ortho > meta > para dichlorobenzenes. 2) K(+)release increased with increase in the number of chlorine. 3) K(+)release increased with increase in the concentration of chlorinated benzene.
en-copyright=
kn-copyright=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生教室
en-keyword=塩化ベンゼン
kn-keyword=塩化ベンゼン
en-keyword=ミトコンドリア
kn-keyword=ミトコンドリア
en-keyword=生体膜
kn-keyword=生体膜
en-keyword=K(+)遊出
kn-keyword=K(+)遊出
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=1-2 suppl
article-no=
start-page=19
end-page=21
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Hemoagglutination inhibiting antibody of Japanese Encephalitis In the sera of inpatients of a hospital in Kurashiki City and that in the sera of an upper secandary school pupils in Kurashiki City (EpidemiologIcal Study on Japanese Encephalitis, 68)
kn-title=倉敷市内某病院入院患者及び倉敷市内某高校生の 日本脳炎血球凝集抑制反応抗体価について （日本脳炎の疫学的研究 68）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The rale of inpatients and high school pupils in Kurashiki City having value under 10 in HI reaclion was 11.4% and 15.2% respectively, suggesting that about one seventh of inhabitants have relatively a few HI antibody just before the season of outbreak of Japanese Encephalitis in Southern part of Okayama Prefecture.
en-copyright=
kn-copyright=

en-aut-name=OgataMasana
en-aut-sei=Ogata
en-aut-mei=Masana
kn-aut-name=緒方正名
kn-aut-sei=緒方
kn-aut-mei=正名
aut-affil-num=1
ORCID=

en-aut-name=MeguroTadamichi
en-aut-sei=Meguro
en-aut-mei=Tadamichi
kn-aut-name=目黒忠道
kn-aut-sei=目黒
kn-aut-mei=忠道
aut-affil-num=2
ORCID=

en-aut-name=KenmotsuKatashi
en-aut-sei=Kenmotsu
en-aut-mei=Katashi
kn-aut-name=劔持堅志
kn-aut-sei=劔持
kn-aut-mei=堅志
aut-affil-num=3
ORCID=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=4
ORCID=

en-aut-name=IshidaTatsuo
en-aut-sei=Ishida
en-aut-mei=Tatsuo
kn-aut-name=石田立夫
kn-aut-sei=石田
kn-aut-mei=立夫
aut-affil-num=5
ORCID=

en-aut-name=HiramatsuMuneshige
en-aut-sei=Hiramatsu
en-aut-mei=Muneshige
kn-aut-name=平松宗成
kn-aut-sei=平松
kn-aut-mei=宗成
aut-affil-num=6
ORCID=

en-aut-name=MorishitaTakayuki
en-aut-sei=Morishita
en-aut-mei=Takayuki
kn-aut-name=森下喬之
kn-aut-sei=森下
kn-aut-mei=喬之
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室

affil-num=5
en-affil=
kn-affil=岡山県環境保健センター

affil-num=6
en-affil=
kn-affil=岡山県環境保健センター

affil-num=7
en-affil=
kn-affil=森下病院
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=11-12
article-no=
start-page=1085
end-page=1089
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19801230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effect of chlorinated mono aromatic hydrocarbons on biological membranes (1. The effect of various concentrations of chlorinated mono aromatic hydrocarbons on normal isolated rat liver mitochondrial oxidative phosphorylation)
kn-title=ベンゼン塩素化合物の生体膜に対する作用 第1報 分離正常ラット肝ミトコンドリアに於ける各化合物の各種濃度の酸化的リン酸化反応に対する影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The effect of mono-, di-, tri-, and tetra-chlorinated benzene on mitochondrial oxidative phosphorylation was determined and the following results were obtained. 1) Chlorinated mono-aromatic hydrocarbons inhibited respiratory control strongly by increasing state 4 respiration and decreasing state 3 respiration. 2) Lower concentrations of mitochondrial protein showed higher inhibitory effects for 1,2,3-tichloro benzene on respiratory control. 3) The respiratory control index decreased with increase in the number of chlorine. 4) The respiratory control index decreased with increase in the concentration of chlorinated benzene. 5) Decrease in respiratory control index was in the order of orth>meta>para-dichloro benzenes. There were differences between the isomers.
en-copyright=
kn-copyright=

en-aut-name=MoriTakaaki
en-aut-sei=Mori
en-aut-mei=Takaaki
kn-aut-name=森孝昭
kn-aut-sei=森
kn-aut-mei=孝昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生
en-keyword=肝臓
kn-keyword=肝臓
en-keyword=ベンゼン塩素化合物
kn-keyword=ベンゼン塩素化合物
en-keyword=ミトコンドリア
kn-keyword=ミトコンドリア
en-keyword=酸化的リン酸化反応
kn-keyword=酸化的リン酸化反応
en-keyword=生体膜
kn-keyword=生体膜
END