岡山大学農学部 Acta Medica Okayama 0474-0254　 98 1 2009 低アレルギー発症性が言及されている鶏卵の機能特性に関する動物実験 31 37 EN Kumiko Nagato Asaki Abe Kiyoaki Narabara Yasuhiro Kondo Functional features concerned with low proallergic natures were examined using an allergy-inducible rat strain (Brown Norway rat; BN rat) on hen's eggs which have been empirically mentioned as hypoallergenic for patients suffering from food allergies (experimental eggs). BN rats were fed on feed containing whole experimental eggs (feed E) and whole normal eggs (control feed, feed C). The densities of immunoglobulin E (IgE)-positive cells, have reported to be IgE-bearing mast cells, in the jejunum and ileum of BN rats fed on experimental-egg-containing feed were lower than those of BN rats fed on normal-egg-containing feed. The number of blood eosinophils was also lower in BN rats fed on feed E. Serum IgE levels were no different between BN rats fed on feed E and feed C. These results indicate that the low proallergic nature of hen's eggs studied in the present study is due to the dereased ability of experimental eggs to facilitate the proliferation and induction of mast cells in the intestinal tissue. No potential conflict of interest relevant to this article was reported.

Acta Medica Okayama 2009 ニワトリ胚とヒナにおけるB細胞分化に関する研究 EN Kiyoaki Narabara No potential conflict of interest relevant to this article was reported.