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ID 19060
Eprint ID
19060
タイトル(別表記)
Studies on the Virus of Infectious Hepatitis in Okayama Prefecture Ⅰ: Purification of the Isolated Virus Ⅱ: Electron Microscopic Study on the Isolated Virus
著者
橋本 良平 岡山大学
抄録(別表記)
Purification and electron microscopic study of the virus isolated by Murakami et al. from the patients of infectious hepatitis in Okayama Prefecture were tried in parallel with animal experiments. The results are summarized as follows: 1) Of all the purification methods tried, the combination of infusion with a saline solution and centrifugation was proved to be the most excellent one for electron microscopic observation and animal experiments. The good efficiency and the simplicity of its procedures also made this method suitable for the purification of the virus of infectious hepatitis. 2) In electron micrographs, the viruses were observed as round or ovoid particles of abo t 50 mμ in diameter. 3) Inoculation of the material containing these particles into mice caused such pathological findings as previously reported by Murakami at el.; a high degree of degeneration or necrosis of liver parenchymal cells accompanied with various cell infiltrations. These observations led the author to the conclusion that the purified particles were nothing but the isolated hepatotropic viruses.
発行日
1958
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
70巻
7号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
2307
終了ページ
2320
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/70/7/70_7_2307/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma