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ID 19820
Eprint ID
19820
フルテキストURL
Thumnail 68_1767.pdf 1.89 MB
タイトル(別表記)
On an Autopsy Case of Osteogenic Sarcoma
著者
木本 哲夫 岡山大学医学部病理学教室
大谷 恭一郎 岡山大学医学部病理学教室
矢部 忠孝 岡山大学医学部病理学教室
武田 俊輝 岡山大学医学部平木内科教室
塩見 文俊 岡山大学医学部平木内科教室
抄録
A review of the literature shows that osteogenic sarcoma is not rare, but the pathologic changes of this disease have not clearly reported yet. It is the purpose of this report to describe the pathohistogenetic changes with the clinical aspects in an autopsy case of osteogenic sarcoma. An adult man, 23 years of age, was admitted to the Hiraki Modical Clinic of the Okayama University Hospital, on August 24, 1953, complaining of chest ache and haemoptoe. The x-ray examination of the chest at that time showed base ball-sized, hard, lobulated masses in the both lungs. The pathological diagnosis was osteogenic sarcoma metastasized in both lungs from the right hemural tumor which amputated in a lower third of the right hemur four years ago. The average size of the tumors in lungs was 5-4 cm in diameter. They were usually nonencapsulated, and the cut surface was solid, firm, and grayish-white. Microscopically, there were two types of the histogenetic origins in tumors of the lung. The first histologic form, which is designated here as the "osteogenic cell sarcoma", showed the following characteristics. Microscopically, the component cells were fairly uniform and generally identical with osteolytic cells in various stages of fetal histogenetic cycles of the bone. There were some areas wherein the neoplastic cells showed atypical orientation and the nuclei were large and slightly dark. Mitoses and neoplasmic giant cells were found occasionally. In many neoplasmic cells the various courses of hyalinisation, carcification and osification were recognized. The second histologic form, which is labeled here as the "chondroblastic cell sarcoma", showed the following characteristics. Microscopically, neoplasmic tissues exhibited the chondroblastic cells, which made it possible to translate to osteolytic cells occasionally in some neoplasmic circumstances, and they were consisted of pleomorphic giant cells with the polymorphic cytoplasmas and numerous mitotic figures. As mentioned above, hyalinisation, carcification and osification were also found graduately in the cytoplasmas of such chondroblastic cells as osteolytic cells. In result of histologic examination, this case was malignant osteogenic sarcoma which showed extensive metastases in both lungs within five years.
発行日
1956-10-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
68巻
10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1767
終了ページ
1775
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/68/10/68_10_1767/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma