タイトル(別表記) Drug-induced liver injury due to the long-term oral administration of rosuvastatin
フルテキストURL 127_219.pdf
著者 大西 理乃| 狩山 和也| 湧田 暁子| 西村 守| 能祖 一裕|
抄録 A 67-year-old man was admitted to our hospital presenting with a liver injury. He had used several types of oral medication for the prior 2 years, including rosuvastatin calcium for hypertension, hyperlipidemia, and prostatic hypertrophy. His liver dysfunction was noted for the first time in February 2013, and at re-examination in March 2013 he showed exacerbation of the liver dysfunction, he was admitted to our hospital at that time. We stopped all of his oral medications, and his liver function improved steadily. We conducted a drug-induced lymphocyte transformation test (DLST), and the rosuvastatin calcium result was positive. He was diagnosed as having a drug-induced (by rosvastatin calcium) liver injury. He resumed oral medications other than rosuvastatin calcium from the time of discharge, with no exacerbation of liver dysfunction since then. Reports of drug-induced liver injury due to drugs with a long-term oral administration are extremely rare. We discuss the relevant literature herein.
キーワード 薬物性肝障害(drug induced liver injury) ロスバスタチンカルシウム(Rosuvastatin) スタチン(statin) DLST
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 219
終了ページ 222
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.219
言語 Japanese
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.219
NAID 130005116815
著者 湧田 暁子|
発行日 2012-03-23
出版物タイトル
資料タイプ 学位論文