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ID 42570
フルテキストURL
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タイトル(別表記)
Studies on the Pathogenic Agent of Infectious Hepatitis in Okayama Prefecture II: Infection by the inoculation of the virus into the caudal vein of the mouse
著者
稲垣 素臣 岡山大学医学部微生物学教室
抄録
In the present section, the author studied comparatively the death by the lethal toxin and the death by the infection of the virus itself. The caudal vein of the mouse was chosen as the site of inoculation, and the establishment of infection was judged by observing the pathological changes of the inoculated mouse. The results were as follows: 1) By the inoculation of the virus into the caudal vein of the mouse, beside the lethal toxin which killed the mouse within about 24 hours, a toxicity was observed to which the mouse succumbed a few days after the inoculation. This toxicity was proved in all tested strains, though somewhat varied according to the strains of the virus. Some cases were observed, however, in which the inoculated mice survived. 2) These two sorts of toxicity were well demonstrated in the chick embryo, particularly in the liver. The emulsion of other materials than the liver showed but a little toxicty. It is inferred, therefore, that the liver of chick-embryo plays a very great role in the manifestation of the toxicity. 3) When the multiplication of the virus was very well, the toxicity of these two kinds was very high. When the multiplication of the virus was bad, the toxicity was low and mice survived. 4) In the case of the death by the lethal toxin, the typical pathological findings could not be observed. In the case of the death by infection, however, the typical prthological changes were observed in high degree. Even in the surviving mice, the pathological changes were slightly observed.
発行日
1957-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
69巻
6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1443
終了ページ
1449
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/69/6/69_6_1443/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma