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ID 18179
Eprint ID
18179
フルテキストURL
Thumnail 80_1091.pdf 2.46 MB
タイトル(別表記)
Studies on (90)YCl(3) Colloid for Clinical Use Part I. Purification of (90)YCl(3) Colloid by Milking Method and the Observation of Electrone Microscopy
著者
立花 明久 岡山大学医学部第1外科教室
抄録
(90)Y is a high-energy radioisotope and emite β-ray with 2.6 days half life. (90)YCl(3) colloid has been used for malignant tumor therapeutically, as (198)Au colloid. In the present experiment, the purification of (90)Y, and the detection of the contaminated (90)Sr was studied. Amberlite XE-100 column was suitable for this prupose. The colloidal size of (90)YCl(3) was transformed by pH, and the features of (90)YCl(3) colloids were observed on electrone microscope. 1) (90)Y and (90)Sr mixture adsorbed on Amberlite XE-100 column (100-200 mesh, 2.5 column volume), and eluted by 0.5 N HCl. (90)Sr is eluted out at 10-60 ml, and (90)Y is eluted out from 170 ml. 2) A mixture of 20 mC of citrate-(90)Y complex and 1μC of (90)Sr fixed on this column, and then eluted by 0.5 N HCl. One drop of eluate at 10 ml was detectable by GM counter. The detectable lower limit of contaminated (90)Sr is 0.1μC by re-counting on GM counter 24 hrs after the elution. 3) Amberlite XE-100 column is suitable for the second column on the milking system, for the purpose of separating the contaminated (90)Sr and (90)Y. This procedure is complete in 1 hr process. 4) (90)YCl(3) colloid is aggregated and formed clamp in high pH solution, Electrone microscopic observations showed that the colloidal size was 40-50 mμ at pH 5, and 20 mμ at pH7.
発行日
1968-12-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
80巻
11-12号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1091
終了ページ
1103
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/80/11-12/80_11-12_1091/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma