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ID 54823
フルテキストURL
Thumnail 71_1_31.pdf 2.05 MB
著者
Waki, Takahiro Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Katsui, Kuniaki Department of Radiology, Okayama University Hospital
Mitsuhashi, Toshiharu Center for Innovative Clinical Medicine, Okayama University Hospital
Ogata, Takeshi Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Katayama, Norihisa Department of Radiology, Okayama University Hospital
Takemoto, Mitsuhiro Department of Radiology, Japanese Red Cross Society Himeji Hospital
Nasu, Yasutomo Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kumon, Hiromi Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kanazawa, Susumu Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
抄録
We investigated differences in seminal vesicle (SV) length and interfractional SV motion relative to the prostate gland in prostate cancer patients. We compared 32 patients who received androgen deprivation therapy (ADT) before radiotherapy with 12 patients receiving radiotherapy alone at Okayama University Hospital in August 2008-July 2011. We examined the right and left SVs’ length and motion by computed tomography (CT) to determine the ADT’s effects and analyzed 347 CT scans in a multiple linear regression model. The ADT patients’ SV length was significantly shorter than the non-ADT patients’. The differences in right and left SV lengths between the ADT and non-ADT patients were 6.8 mm (95% CI 2.0-11.7 mm) and 7.2 mm (95% CI 3.1-11.3 mm) respectively in an adjusted regression model. SV motion did not differ between the ADT and non-ADT patients in terms of interfractional motion of the SV tips and the SVs’ center relative to the prostate gland. The ADT patients had significantly shorter SVs compared to the non-ADT patients, but no difference in SV motion was observed. SV interfractional motion should thus be compensated using the same planning margins, regardless of whether ADT is used.
キーワード
prostate cancer
androgen deprivation therapy
seminal vesicle length
seminal vesicle motion
imageguided radiotherapy
発行日
2017-02
出版物タイトル
Acta Medica Okayama
71巻
1号
出版者
Okayama University Medical School
開始ページ
31
終了ページ
39
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Amo Type
Original Article
Submission Path
amo/vol71/iss1/5
JaLCDOI