fulltext.pdf 407 KB
Itoshima, Tatsuya Okayama University
Fedail, Sulieman S. Ibn Sina Hospital
Suliman, Ikhlas Ibn Sina Hospital
Ali, Abbas K.
Higashi, Toshihiro Okayama University
Tsuji, Takao Okayama University
Markers of hepatitis A and B virus were tested in 88 adult Sudanese subjects in Khartoum, Sudan. The subjects consisted of 25 control hospitalized patients, 21 volunteer blood donors, 23 patients with hepatosplenic schistosomiasis, 13 patients with liver cirrhosis and 6 patients with hepatocellular carcinoma (HCC). Antibody to hepatitis A virus was detected in 96% of the total. Hepatitis B surface antigen (HBsAg) was positive in 4, 24, 22, 31, and 67% of the subject groups, respectively. Antibody against hepatitis B core antigen (HBcAb) of undiluted serum was positive in 60, 57, 65, 77 and 83%, and there was no difference in incidence among the groups. It was positive in 200X diluted serum in 4, 24, 17, 23 and 60%. HBsAg and HBcAb (200X) were detected more often in HCC patients than in the control subjects (p less than 0.01). Hepatitis B virus is an important factor in the etiology of HCC in the Sudan.
hepatitis B virus markers
Acta Medica Okayama
Okayama University Medical School
|Web of Sience KeyUT|