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ID 31932
JaLCDOI
フルテキストURL
著者
Takahishi, Isao Okayama University
Yorimitsu, Seiichi Okayama University
Hara, Masamichi Okayama University
Inagaki, Toshihiro Okayama University
Nakada, Hiroyuki Okayama University
Sekito, Noriko Okayama University
Hayashi, Naoki Okayama University
Nonaka, kenichi Okayama University
Ohmoto, Eijiro Okayama University
Uchida, Kouzaburo Okayama University
Takizawa, Michihiro Okayama University
Kimura, Ikuro Okayama University
Sanada, Hiroshi Okayama University Hospital
Adachi, Tomiro Okayama Shimin Hospital
Tsubota, Teruhiko Okayama Shimin Hospital
Kitajima, Koichi Okyama University School of Allied Medical Science
抄録

Thirteen previously untreated patients aged 70 and above with acute nonlymphocytic leukemia were treated with aclarubicin (ACR) alone. Among 10 cases (3, acute myelocytic leukemia; 4, acute myelomonocytic leukemia; 2, acute monocytic leukemia; and one, acute erythroleukemia) in which an evaluation was possible, 5 cases (3, acute myelomonocytic leukemia; and 2, acute monocytic leukemia) obtained complete remission (CR). The CR rate was 83% in 6 patients with acute myelomonocytic leukemia or acute monocytic leukemia. The median CR duration and survival was 7.5 and 10 + months, respectively. Although side effects of the drug on digestive system such as nausea, vomiting and anorexia were observed in all patients, they were controllable by conventional treatments. The results suggest that ACR is effective for the clinical management of elderly patients with acute nonlymphocytic leukemia, especially those with acute myelomonocytic leukemia or acute monocytic leukemia.

キーワード
acute leukemia in elderly patients
chemotherapy of acute leukemia
aclarubicin
Amo Type
Article
発行日
1986-06
出版物タイトル
Acta Medica Okayama
40巻
3号
出版者
Okayama University Medical School
開始ページ
175
終了ページ
177
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT