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ID 31557
JaLCDOI
フルテキストURL
著者
Kuroda, Masahiro Okayama University Kaken ID researchmap
Hizuta, Akio Okayama University
Iwagaki, Hiromi Okayama University
Makihata, Eiichi Okayama University
Asaumi, Junichi Okayama University Kaken ID researchmap
Nishikawa, Koji Okayama University
Gao, Xian Shu Okayama University
Nakagawa, Tomio Okayama University
Togami, Izumi Okayama University
Takeda, Yoshihiro Okayama University Kaken ID
Joja, Ikuo Okayama University
Kawasaki, Shoji Okayama University
Orita, Kunzo Okayama University
Hiraki, Yoshio Okayama University
抄録

Between November 1984 and August 1992 we used hyperthermotherapy in six cases of local recurrence of rectal cancer. Hyperthermotherapy was performed on the average 8.7 times (range: 3-18) for each patient for 60 min each. All patients underwent combined radiotherapy and received a mean radiation dose of 42.5 Gy (range: 9-60 Gy). Five patients underwent heating within 1 h after irradiation and one patient simultaneously with the irradiation. Four patients underwent combined chemotherapy and two patients immunotherapy. Before the treatment all patients had painful lesions, but pain decreased posttherapeutically in five patients. Performance status improved in two patients. High carcinoembryonic antigen levels prior to the therapy in four patients decreased in all cases after treatment. Posttherapeutical computed tomograms revealed only minor response or no changes. After the treatment, four patients died of exacerbations of recurrent tumors and one patient of distant metastases. The patient who underwent simultaneous radiohyperthermotherapy is presently alive, in August 1992, 38 months after initiation of the treatment. The 50% survival time after initiation of the treatment was 25 months (range: 10-38 months). Hyperthermotherapy combined with radiotherapy, chemotherapy and/or immunotherapy was useful for the alleviation of pain in patients who developed local recurrence after surgery, and improved survival after recurrences can be expected.

キーワード
rectal cancer
local recurrence
hyperthermia
radiotherapy
chemotherapy
Amo Type
Article
発行日
1993-08
出版物タイトル
Acta Medica Okayama
47巻
4号
出版者
Okayama University Medical School
開始ページ
249
終了ページ
254
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT