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ID 31599
JaLCDOI
フルテキストURL
Thumnail fulltext.pdf 1.18 MB
著者
Kuroda, Masahiro Okayama University Kaken ID researchmap
Tsushima, Tomoyasu Okayama University
Nasu, Yasutomo Okayama University Kaken ID researchmap
Asaumi, Junichi Okayama University Kaken ID researchmap
Nishikawa, Koji Okayama University
Gao, Xian Shu Okayama University
Joja, Ikuo Okayama University
Takeda, Yoshihiro Okayama Univresity Kaken ID
Togami, Izumi Okayama University
Makihata, Eiichi Okayama University
Kawasaki, Shoji Okayama University
Ohmori, Hiroyuki Okayama University
Hiraki, Yoshio Okayama University
抄録

We performed a long-term follow-up of 4 patients with penile cancer who underwent hyperthermotherapy from August 1985 until August 1992. Hyperthermia was applied using a frequency of 350 MHz with a waveguide applicator twice a week for 60 min each for an average of 9.5 times (varying from 6 to 13 times). The total heating time that the temperature of urethra could be kept above 42 degrees C, was 166 min on the average (ranging from 0 to 463 min). Two patients classified as stage I according to the Jackson classification and 1 patient classified as stage IV underwent combined radiotherapy and received an average radiation dose of 53 Gy (range, 40-70 Gy). Among these patients 2 underwent combined chemotherapy with bleomycin or peplomycin. Malignant cells disappeared posttherapeutically and in August 1992, after an average of 5 years and 9 months (varying from 4 years 6 months to 6 years 10 months), the patients were free of recurrences. The one patient on stage IV had extensive invasion of the abdominal wall, but still recovered completely. One patient on stage III underwent combined chemotherapy and hyperthermotherapy, but heating had obviously been insufficient. There was a residue of malignant cells after the treatment and we performed a penectomy. Regarding functional preservation of the penis a multidisciplinary therapy incorporating hyperthermotherapy can be expected to increase the curativity. This indicates that it could induce in an advanced case, where an operation would be difficult, complete remission.

キーワード
penile cancer
hyperthermia
radiotherapy
chemotherapy
Amo Type
Article
発行日
1993-06
出版物タイトル
Acta Medica Okayama
47巻
3号
出版者
Okayama University Medical School
開始ページ
169
終了ページ
174
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT