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ID 30706
JaLCDOI
フルテキストURL
Thumnail fulltext.pdf 1.43 MB
著者
Hamasaki, Kazuhide Okayama University
抄録

Six established Japanese Burkitt lymphoma (BL) cell lines including one case with null cell type were studied by chromosomal banding techniques. The modal chromosome number was diploid or nearly diploid in five cases and hyperdiploid in one case. The marker chromosome 14q+ was observed in four of the six cases; the origin of the extra band was a chromosome 8 in three including the null cell case but could not be identified in the other. The two cases lacking the 14q+ marker had variant translocations involving the long arm of chromosome 8, one of which carried a translocation, t(8;22) (q24;q13) and the other a translocation, t(2;8) (p12;q24). Although structural and/or numerical aberrations were found in all six cell lines, chromosome 8 was the one most consistently involved. This frequent involvement of chromosome 8 in aberrations; therefore, may be an important event in the development of BL rather than the presence of a 14q+ marker chromosome.

キーワード
non-African Burkitt lymphoma cell line
null cell type Burlitt lymphoma cell line
translocation
Amo Type
Article
発行日
1982-02
出版物タイトル
Acta Medica Okayama
36巻
1号
出版者
Okayama University Medical School
開始ページ
23
終了ページ
38
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT