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ID 52790
JaLCDOI
フルテキストURL
著者
Wada, Nozomu Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Yasunaka, Tetsuya Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ikeda, Fusao Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Nishina, Sohji Department of Hepatology and Pancreatology, Kawasaki Medical University
Korenaga, Masaaki Department of Hepatology and Pancreatology, Kawasaki Medical University
Hino, Keisuke Department of Hepatology and Pancreatology, Kawasaki Medical University
Fujioka, Shin-ichi Department of Internal Medicine, Okayama Saiseikai General Hospital
Osawa, Toshiya Department of Internal Medicine, Okayama Saiseikai General Hospital
Itoshima, Tatsuya Department of Internal Medicine, Okayama Saiseikai General Hospital
Kawanaka, Miwa Department of Internal Medicine, Center for Liver Diseases, Kawasaki Hospital, Kawasaki Medical School
Yamada, Gotaro Department of Internal Medicine, Center for Liver Diseases, Kawasaki Hospital, Kawasaki Medical School
Kariyama, Kazuya Department of Liver Disease Center, Okayama City Hospital
Takayama, Hiroki Department of Gastroenterology, Tsuyama Central Hospital
Kubota, Junichi Department of Gastroenterology, Tsuyama Central Hospital
Morimoto, Yoichi Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Mizushima, Takaaki Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Yamashita, Haruhiko Department of Gastroenterology, National Hospital Organization Okayama Medical Center
Tanioka, Hiroaki Department of Internal Medicine, Okayama Rousai Hospital
Negoro, Yuji Department of Gastroenterology, Okayama Red Cross Hospital
Toshimori, Junichi Department of Gastroenterology, Okayama Red Cross Hospital
Kobashi, Haruhiko Department of Gastroenterology, Okayama Red Cross Hospital
Hirano, Atsushi Department of Internal Medicine, National Hospital Organization Minami-Okayama Medical Center
Itano, Yasuo Department of Internal Medicine, Okayama Kyoritsu General Hospital
Takaki, Akinobu Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID
Yamamoto, Kazuhide Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
抄録
Hepatitis B virus (HBV) is one of the major viruses causing acute hepatitis. Recently, the incidence of acute hepatitis with genotype A has been increasing in Japan. The aim of this study was to investigate acute hepatitis B (AHB) in Okayama prefecture, with special attention to HBV genotype A. AHB patients who visited one of 12 general hospitals in Okayama prefecture between 2006 and 2010 were retrospectively analyzed. Over the course of the study period, 128 patients were diagnosed with AHB. Sexual transmission was supposed in the majority of patients (78 patients, 61%), including 59 (76%) having sex with heterosexual partners. The genotypes of HBV were assessed in 90 patients (70%), of whom 27 patients were infected with genotype A, 5 with genotype B, and 58 with genotype C. The prevalence of genotype A was significantly higher among male patients (28.7%), aged 20-29 (35.6%, p<0.01), among men who had sex with men (100%, p<0.005), and among patients having sex with unspecified partners (44.8%, p<0.005). Genotype A was not a significant factor associated with delayed HBsAg disappearance. Caution should be exercised with regard to sexually transmissible diseases in order to slow the pandemic spread of AHB due to genotype A.
キーワード
acute hepatitis
hepatitis B virus
Amo Type
Original Article
発行日
2014-08
出版物タイトル
Acta Medica Okayama
68巻
4号
出版者
Okayama University Medical School
開始ページ
243
終了ページ
247
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT