JaLCDOI 10.18926/AMO/31904
フルテキストURL fulltext.pdf
著者 Motokura, Kiyoshi| Tani, Kazuyoshi| Ugaki, Masaaki| Sato, Shiro| Takata, Choji| Naito, Takakazu| Nabeshima, Saburo| Yamasaki, Ryohei| Yamamoto, Michio| Nishishita, Soichi| Nobuki, Shigeo| Tanimoto, Junichi| Kojima, Sumikazu| Shiaku, Midori| Iguchi, Yoshiko|
抄録 <p>With the purpose of revealing the biological effects of the X-ray irradiation the authors extracted phospholipids from the liver of irradiated animals and proved that this substance has the action to inhibit the growth of the bone marrow cells, the motility of pseudo-eosinophilis and the erythropoiesis in tissue culture, suggesting that the injury will mainly be induced by the toxic substances produced by irradiation.</p>
Amo Type Article
発行日 1960-04
出版物タイトル Acta Medicinae Okayama
14巻
1号
出版者 Okayama University Medical School
開始ページ 46
終了ページ 54
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
NAID 120002312680
JaLCDOI 10.18926/AMO/31898
フルテキストURL fulltext.pdf
著者 Yamamoto, Michio| Tanimoto, Junichi| Kojima, Sumikazu| Nobuki, Shigeo| Hagitani, Akira| Iguchi, Yoshiko| Akagi, Eiko| Ofuji, Tadashi| Asaka, Takakazu| Kamura, Junta| Shibata, Tsuneo|
抄録 <p>The unsaturated fatty acid fraction extracted from the liver of rabbit irradiated with X-rays exerts a strong cytotoxic effect on human coelothelioma cells and Yoshida sarcoma cells both in vitro and in vivo. The cell damage seems to initiate at the nucleus, finally leading to the complete cytolysis. The inhibiting effect of this substance on the mitosis of Yoshida sarcoma cells can be observed, especially marked from prophase up to metaphase giving almost the same results obtained after X-ray irradiation. From these results and the observations reported by several authors on the cell damage by X-ray irradiation, weshould call special attention to the fact that the essential mechanism of X-ray irradiation can be attributed to the cell toxin produced after the irradiation.</p>
Amo Type Article
発行日 1960-04
出版物タイトル Acta Medicinae Okayama
14巻
1号
出版者 Okayama University Medical School
開始ページ 55
終了ページ 67
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
NAID 120002313084