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ID 56412
フルテキストURL
著者
Takami, Tsuneaki Institute of Plant Science and Resources, Okayama University
Ohnishi, Norikazu Institute of Plant Science and Resources, Okayama University
Kurita, Yuko Faculty of Agriculture, Ryukoku University
Iwamura, Shoko Department of Biology, Graduate School of Science, Kobe University
Ohnishi, Miwa Department of Biology, Graduate School of Science, Kobe University
Kusaba, Makoto Graduate School of Science, Hiroshima University
Mimura, Tetsuro Department of Biology, Graduate School of Science, Kobe University
Sakamoto, Wataru Institute of Plant Science and Resources, Okayama University
抄録
Mitochondria and chloroplasts (plastids) both harbour extranuclear DNA that originates from the ancestral endosymbiotic bacteria. These organelle DNAs (orgDNAs) encode limited genetic information but are highly abundant, with multiple copies in vegetative tissues, such as mature leaves. Abundant orgDNA constitutes a substantial pool of organic phosphate along with RNA in chloroplasts, which could potentially contribute to phosphate recycling when it is degraded and relocated. However, whether orgDNA is degraded nucleolytically in leaves remains unclear. In this study, we revealed the prevailing mechanism in which organelle exonuclease DPD1 degrades abundant orgDNA during leaf senescence. The DPD1 degradation system is conserved in seed plants and, more remarkably, we found that it was correlated with the efficient use of phosphate when plants were exposed to nutrient-deficient conditions. The loss of DPD1 compromised both the relocation of phosphorus to upper tissues and the response to phosphate starvation, resulting in reduced plant fitness. Our findings highlighted that DNA is also an internal phosphate-rich reservoir retained in organelles since their endosymbiotic origin.
備考
This is an Accepted Manuscript of an article published by Springer Nature Publishing AG
発行日
2018-05-12
出版物タイトル
Nature Plants
4巻
出版者
Springer Nature Publishing AG
開始ページ
1044
終了ページ
1055
ISSN
20550278
NCID
AA1273934X
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
論文のバージョン
author
PubMed ID
DOI
関連URL
isVersionOf https://doi.org/10.1038/s41477-018-0291-x