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Lai, Miinyuh Okayama University
Hamasaki, Kazuhide Okayama University
Tokioka, Masaaki Okayama University
Tsubota, Teruhiko Okayama University
Nakata, Yasunari Okayama University
Kitajima, Koichi Okayama University
Kimura, Ikuro Okayama University
Sanada, Hiroshi Okayama University
A 30 year old female patient diagnosed as acute lymphoblastic leukemia (ALL) with hand mirror like configuration of lymphoblastic-lymphocytic cells is reported. Although the leukemia was resistant to conventional chemotherapeutic regimens, the patient always looked well and survived for more than 20 months. Surface marker analysis showed that the cell was non-T, non-B, and not reactive to antiserum against common ALL antigen. A cytogenetic study of all the analyzable metaphases of the direct bone marrow preparation had a normal female karyotype. The clinical and hematological course is described. The immunological significance and the influence of hand mirror cell on chemosensitivity and prognosis are discussed.
acute lymphoblastic leukemia
hand mirror cell leukemia.
Acta Medica Okayama
Okayama University Medical School
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