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ID 30448
JaLCDOI
フルテキストURL
著者
Haruta, Yuro Kochi Municipal Central Hospital
Takahashi, Isao Kochi Municipal Central Hospital
Sekito, Noriko Okayama University
Miyamoto, Kanji Okayama University
Shimamoto, Masaaki Shimamoto Hospital
Wakita, Yoshiharu Kochi Municipal Central Hospital
Kikkawa, Kiyoshi Kochi Municipal Central Hospital
Nakamura, Toru Kochi Municipal Central Hospital
Seto, Takumi Kochi Municipal Central Hospital
Yamashita, Jiro Kochi Municipal Central Hospital
Yorimiysu, Seiichi Kochi Municipal Central Hospital
Miyake, Susumu Kochi Municipal Central Hospital
Machida, Ken-ichi Kochi Municipal Central Hospital
Kimura, Ikuro Okayama University
抄録

A rare case of variant Philadelphia (Ph1) chromosome positive [46, XX, t (9; 22) (q34; q11), inv (9) (9q22; 22q13)] chronic myelocytic leukemia (CML) was described. The patient, 73 years old female, was hospitalized to our hospital because of leukocytosis. Hematological findings corresponded to those of CMLs. However, this case lacked hepatosplenomegaly. Southern blot analysis using a 3 breakpoint cluster region (bcr) probe revealed a bcr rearrangement. The patient has been in the chronic phase for sixteen months without treatment. Clinical and chromosomal changes are under observation in order to get accumulate data for a pathophysiological analysis of variant Ph1 positive CMLs.

キーワード
variant Ph1 positive chronic myelocytic leukemia
bcr rearrangement
Amo Type
Article
発行日
1990-10
出版物タイトル
Acta Medica Okayama
44巻
5号
出版者
Okayama University Medical School
開始ページ
283
終了ページ
286
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT