JaLCDOI 10.18926/AMO/32727
フルテキストURL fulltext.pdf
著者 Ohtsuki, Hisashi|
抄録 <p>A factor, cornin, inhibiting the growth of L cells cultured in monolayer was extracted from bovine liver with boiling water and was partially purified by gel filtration with Sephadex G-200. The factor was (1) precipitable with ethanol at the concentration between 70% and 90%, (2) impermeable through dializing memo brane, (3) eluted as the last peak at the gel filtration and (4) containing protein and RNA but no DNA.</p>
Amo Type Article
発行日 1974-02
出版物タイトル Acta Medica Okayama
28巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 6
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 4275644
JaLCDOI 10.18926/AMO/32724
フルテキストURL fulltext.pdf
著者 Ohtsuki, Hisashi|
抄録 <p>Gornin was extracted from bovine liver. The effects of cornin on DNA synthesis were compared with its effects on cell growth using L cells growing in suspension. As the first step of this experiment, a simple method of suspension culture was established with a new modification of YLE medium. Both effects of cornin paralleled with dosage. And the properties of the inhibitory factor of DNA synthesis are the same as those of growth inhibitor in respect to the heat stability and impermeability against dialyzing membrane. The inhibitor of DNA synthesis could not be separated from that of growth by gel filtration with Sephadex G-75.</p>
Amo Type Article
発行日 1974-02
出版物タイトル Acta Medica Okayama
28巻
1号
出版者 Okayama University Medical School
開始ページ 7
終了ページ 17
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 4276080
NAID 120002311984